Anti-CD49b (Integrin alpha 2) Antibodies

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CD49b (Integrin alpha 2) Antibodies

Antibodies that detect CD49b (Integrin alpha 2) can be used in several scientific applications, including Flow Cytometry, Immunohistochemistry, Western Blot, Immunocytochemistry and Immunoprecipitation. These antibodies target CD49b (Integrin alpha 2) in Mouse, Human, Non-human primate, Rat and Porcine samples. Our CD49b (Integrin alpha 2) monoclonal, polyclonal and recombinant monoclonal antibodies are developed in Rat, Mouse, Rabbit, Armenian Hamster and Sheep. These antibodies have been verified by Relative Expression and Knockout to confirm specificity to CD49b (Integrin alpha 2). Find the CD49b (Integrin alpha 2) antibody that fits your needs. Choose from 1 of 61 CD49b ... View more Antibodies that detect CD49b (Integrin alpha 2) can be used in several scientific applications, including Flow Cytometry, Immunohistochemistry, Western Blot, Immunocytochemistry and Immunoprecipitation. These antibodies target CD49b (Integrin alpha 2) in Mouse, Human, Non-human primate, Rat and Porcine samples. Our CD49b (Integrin alpha 2) monoclonal, polyclonal and recombinant monoclonal antibodies are developed in Rat, Mouse, Rabbit, Armenian Hamster and Sheep. These antibodies have been verified by Relative Expression and Knockout to confirm specificity to CD49b (Integrin alpha 2). Find the CD49b (Integrin alpha 2) antibody that fits your needs. Choose from 1 of 61 CD49b (Integrin alpha 2) antibodies, which have been validated in experiments with 429 publications and 199 images featured in our data gallery.

Browse primary antibodies for WB, Flow, IHC, ICC/IF, ELISA, IP, and other applications. Antibodies with Advanced Verification data have been validated for specificity to ensure that the antibody binds to the antigen stated. If you cannot find the antibody you're looking for, contact us today to develop custom antibodies for specific targets, species and applications.

Target Information

CD49b (Integrin alpha 2, Integrin alpha 2 chain, VLA-2 alpha chain, HM alpha 2) is a member of the integrin family. It is a glycoprotein with molecular weight of 150 kD, and it complexes with CD29 (Integrin beta 1) to form the heterodimeric integrin VLA-2 (integrin alpha 2 beta 1, or GPIa/IIa) complex. VLA-2 is an extracellular receptor for laminin, collagen, and fibronectin, and interaction with its ligands results in the activation of intracellular signaling pathways. It has reported roles in VEGF-induced angiogenesis in vivo, as well as adhesion and lymphocyte activation. CD49b is expressed by NK cells, NK-T cells, monocytes, platelets, and epithelial cells. It is also expressed on adaptive immune cells such as T and B cells, specifically on a subset of CD4+ T cells in the spleen, on intraepithelial and lamina propria lymphocytes in the intestine, as well as on a population of peripheral CD4+ type 1 T regulatory (Tr1) cells that co-express LAG-3.

Synonyms

alpha 2 subunit of VLA-2 receptor; BDPLT9; BR; CD49 antigen-like family member B; CD49B; Collagen receptor; DX5; GPIa; HPA-5; human platelet alloantigen system 5; integrin alpha 2; integrin alpha-2; integrin subunit alpha 2; integrin, alpha 2; integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor); Itga2; platelet antigen Br; platelet glycoprotein GPIa; platelet membrane glycoprotein Ia; very late activation protein 2 receptor, alpha-2 subunit; VLA-2; VLA2 receptor; VLA-2 receptor, alpha 2 subunit; VLA-2 subunit alpha; VLAA2

Target Video

6320249796112

CD49b (Integrin alpha 2) antibodies from Thermo Fisher Scientific

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Learn more about CD49b (Integrin alpha 2) primary antibodies that can be used in Flow Cytometry, Immunohistochemistry, Western Blot and Immunocytochemistry in Mouse, Human, Non-human primate and Rat samples.