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Autoimmune Diseases

Currently there are more than 120 different autoimmune diseases. Although perceived as rare, autoimmune diseases affect up to 8% of the population.1 Frequently these diseases, when undiagnosed and untreated, are associated with a poor prognosis for the patient. In many autoimmune diseases, particularly early in the disease course —when it is most modifiable—patients often present with overlapping clinical features, making diagnosis by symptoms alone nearly impossible.2

Using clinical diagnostics from your local pathology laboratory to look beneath the surface in this clinically challenging field can provide key diagnostic clues to aid your differential diagnosis. This can mean that your patient is diagnosed sooner in the course of their disease.

Therefore, receiving relevant, often disease modifying, treatment sooner can potentially have a significant impact on their prognosis and ultimately their satisfaction.

Learn more about best practice in the identification and management of these autoimmune diseases:

A Threat to Women2

Autoimmune diseases affect millions of people worldwide; however, for women, the threat is even more real. Data highlights that gender bias towards females is high (9:1),3 in the majority of autoimmune diseases; but prevalence can be especially high in certain diseases, such as Thyroid Diseases, Systemic Lupus Erythematosus (SLE), and Sjögren’s Syndrome.

These diseases also dominate the list of the top ten leading causes of death among women.3,4

75% of people with any autoimmune disease are women3

How to order a test

Benefits of In Vitro Diagnostic Testing

Patients often present initial symptoms that are intermittent and nonspecific until a disease becomes acute. When a patient's clinical presentation offers a wide range of diagnoses possibilities, in vitro diagnostic tests can be used to identify the presence of antibodies that may suggest autoimmune inflammatory disease. This vital information can help support the ruling-in or ruling-out of multiple autoimmune diseases to support disease identification while there is still time to intervene.

References
  1. Progress in Autoimmune Disease Research. National Institute of Health, Autoimmune Disease Coordinating Committee. 2005, www.niaid.nih.gov/sites/default/files/adccfinal.pdf. Accessed December 2017.
  2. Autoimmune Disease Research Center at the Johns Hopkins Medical Institutions. Broad Spectrum of AutoImmune Disease. http://autoimmune.pathology.jhmi.edu/whatis_spectrum.cfm. Accessed October 2017.
  3. Ngo, ST, Steyn FJ, McCombe PA. Gender Differences in Autoimmune Disease. Frontiers in Neuroendocrinology. 2014;347-369. www.sciencedirect.com/science/article/pii/S0091302214000466#s0180. Accessed October 2017.
  4. Walsh, SJ, Rau LM.  Autoimmune Diseases: A Leading Cause of Death among Young and Middle-Aged Women in the United States. Am J Public Health. 2000;90:1463-1465.