ImmunoCAP Specific IgE Tests The Gold Standard Specific IgE Test Portfolio
We offer a broad selection of specific IgE tests, including atopy tests, whole allergens to allergen components, helping healthcare providers to accurately diagnose and manage allergic diseases, including asthma. The broad menu of allergens offered, in combination with more than 50 years of experience in allergen development and more than 6,000 publications,1 has led to ImmunoCAP™ being referred to as gold standard sIgE blood test technology.2
Our Specific IgE Menu
- ImmunoCAP Phadiatop/Phadiatop Infant
A single test to help rule in or rule out atopic allergy, a tendency to produce an IgE mediated response to protein(s) in the environment e.g., pollen, house dust mite, and pets. - ImmunoCAP Whole Allergens
More than 550 different whole allergens and allergen mixes help identify allergic triggers. - ImmunoCAP Allergen Components
More than 100 allergen components help clinicians differentiate between primary sensitization and cross-reactivity, assess the risk for systemic reactions, and determine allergens for successful immunotherapy.3,4
Quantitative test results you can trust, enabled through high-quality standards
Our high-quality production standards ensure proven, reliable, and reproducible results for the quantitative detection of specific IgE antibodies. The quantitative test result can help make accurate diagnoses, follow the disease development, and predict development of allergic disease.5-13 The limit of detection is as low as 0.1 kUA/l.5,14
ImmunoCAP tests can be performed on any patient
ImmunoCAP specific IgE blood test can be performed with few limitations. Unlike traditional skin-prick testing (SPT), an ImmunoCAP blood test:
- Can be performed irrespective of a patient’s age, skin condition, medication, symptom, disease activity, pregnancy, and even in early infancy.15-19
- Poses no risk for anaphylaxis.15,19
- Is not subject to interference by exogenous biotin supplementation.20
These products may not be cleared for use in your country. Please contact your sales representative for information about specific product availability.
1. Data on File. Thermo Fisher Scientific. July 2017.
2. Crameri, R., In vitro allergy diagnosis – Allergen -specific IgE. In: Akdis, C A; Agache, I. EAACI Global Atlas of Allergy. Zurich: European Academy of Allergy and Clinical Immunology, 2014.
3. Canonica, G.W., et al., A WAO - ARIA - GA(2)LEN consensus document on molecular-based allergy diagnostics. World Allergy Organ J, 2013. 6(1): p. 17.
4. Matricardi, P.M., et al., EAACI Molecular Allergology User's Guide. Pediatr Allergy Immunol, 2016. 27 Suppl 23: p. 1-250.
5. van Hage, M., C. Hamsten, and R. Valenta, ImmunoCAP assays: Pros and cons in allergology. J Allergy Clin Immunol, 2017. 140(4): p. 974-977.
6. Soderstrom, L., et al., A further evaluation of the clinical use of specific IgE antibody testing in allergic diseases. Allergy, 2003. 58(9): p. 921-8.
7. Sampson, H.A., Utility of food-specific IgE concentrations in predicting symptomatic food allergy. J Allergy Clin Immunol, 2001. 107(5): p. 891-6.
8. Illi, S., et al., The natural course of atopic dermatitis from birth to age 7 years and the association with asthma. J Allergy Clin Immunol, 2004. 113(5): p. 925-31.
9. Wood, R.A., The likelihood of remission of food allergy in children: when is the optimal time for challenge? Curr Allergy Asthma Rep, 2012. 12(1): p. 42-7.
10. Eigenmann, P.A., et al., Testing children for allergies: why, how, who and when: an updated statement of the European Academy of Allergy and Clinical Immunology (EAACI) Section on Pediatrics and the EAACI-Clemens von Pirquet Foundation. Pediatr Allergy Immunol, 2013. 24(2): p. 195-209.
11. Pfaar, O., et al., Perspectives in allergen immunotherapy: 2019 and beyond. Allergy, 2019. 74 Suppl 108: p. 3-25.
12. UKNEQAS for specific IgE: Pooled CV (%) during 2011-2017.
13. Quality Club Specific IgE; pooled CV (%) during 2003-2017.
14. Directions for use. ImmunoCAP specific IgE.
15. Siles, R.I. and F.H. Hsieh, Allergy blood testing: A practical guide for clinicians. Cleve Clin J Med, 2011. 78(9): p. 585-92.
16. Bonnelykke, K., C.B. Pipper, and H. Bisgaard, Sensitization does not develop in utero. J Allergy Clin Immunol, 2008. 121(3): p. 646-51.
17. Belhocine, W., et al., Total serum tryptase levels are higher in young infants. Pediatr Allergy Immunol, 2011. 22(6): p. 600-7.
18. Bacharier, L.B., et al., Diagnosis and treatment of asthma in childhood: a PRACTALL consensus report. Allergy, 2008. 63(1): p. 5-34.
19. Walsh, J. and N. O'Flynn, Diagnosis and assessment of food allergy in children and young people in primary care and community settings: NICE clinical guideline. The British journal of general practice : the journal of the Royal College of General Practitioners, 2011. 61(588): p. 473-475.
20. ImmunoDiagnostics Statment, No Biotin Interference in ImmunoCAPTM Assays. Uppsala, Jan 31 2018.