With ImmunoCAP™ Specific IgG tests, the concentration of circulating allergen-specific IgG antibodies in human serum or plasma can be determined.1 These antibodies are part of the natural defense system of the body and develop in response to contact with foreign substances. The ImmunoCAP portfolio offers testing for common environmental allergens/antigens that may cause an exaggerated immune response,2 e.g., bacterial, fungal, animal, plant, and chemical substances.3
Measuring specific IgG antibodies may provide a range of valuable clinical information in several fields.
In allergic disease, these are some examples of how specific IgG test results are used:
There is no common cut-off value for above normal levels of circulating specific IgG antibodies, as these are markers for allergen exposure, which may not be directly related to the disease and will depend on the local environment and levels of exposure.7