|Western Blot (WB)||1:500-1:1000|
|Tested Species reactivity||Human, Mouse, Rat|
|Host / Isotype||Rabbit / IgG|
|Immunogen||A synthetic phosphopeptide derived from human TFII-I around the phosphorylation site of Tyr248 (P-D-YP-Y-Q)|
|Purification||Antigen affinity chromatography|
|Storage buffer||Dulbecco's PBS, pH 7.4, with 50% glycerol, 150mM NaCl|
|Contains||0.02% sodium azide|
GTF2I is a multifunctional phosphoprotein with roles in transcription and signal transduction. It is deleted in Williams-Beuren syndrome, a multisystem developmental disorder caused by the deletion of contiguous genes at chromosome 7q11.23.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: BAP-135; BAP135; Bruton tyrosine kinase-associated protein 135; BTK-associated protein 135; BTK-associated protein, 135kD; General transcription factor II-I; GTF2I; GTFII-I; SPIN; SRF-Phox1-interacting protein; TFII-I; WBSCR6; Williams-Beuren syndrome chromosomal region 6 protein; Williams-Beuren syndrome chromosome region 6
Gene Aliases: 6030441I21Rik; BAP-135; BAP135; BTKAP1; DIWS; Diws1t; GTF2I; Gtf2ird1; GTFII-I; IB291; SPIN; TFII-I; WBS; WBSCR6
Molecular Function: transcription factor
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