Thermo Scientific Chemicals

1,1,3,3-Tetramethylguanidine, 99%, Thermo Scientific Chemicals

Catalog number: A12314.AC
25 mL, Each
Thermo Scientific Chemicals

1,1,3,3-Tetramethylguanidine, 99%, Thermo Scientific Chemicals

Catalog number: A12314.AC
25 mL, Each
Quantity
Catalog number: A12314.AC
Price (USD)
Price: 27.70
Online price: 23.65
Your price:
Quantity
-

Chemical Identifiers

CAS
80-70-6
IUPAC Name
N,N,N',N'-tetramethylguanidine
Molecular Formula
C5H13N3
InChI Key
KYVBNYUBXIEUFW-UHFFFAOYSA-N
SMILES
CN(C)C(=N)N(C)C
Appearance (Color)
Clear colorless to yellow
Assay (GC)
≥98.5% (UK sourced material)
Assay from Supplier's CofA
≥98.5% (US sourced material, GC)
Refractive Index
1.4665-1.4695 @ 20?C (UK sourced material)
Form
Liquid

Description

1,1,3,3-Tetramethylguanidine is employed as a polyurethane foam catalyst, as an accelerator for the syntheses of polysulfured rubber. It is also used as a strong base in the photochemical (couplers) and in the pharmaceutical (steroids) industries. It is essential for the preparation of alkyl nitriles from alkyl halides and 3'-alkylthymidines from 3'-nitrothymidines. It serves as an efficient and selective catalyst for the benzoylation of alcohols. It replaces the expensive bases 1,8-Diazabicyclo[5.4.0]undec-7-ene (DBU) and 1,5-Diazabicyclo[4.3.0]non-5-ene (DBN) in organic synthesis.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
1,1,3,3-Tetramethylguanidine is employed as a polyurethane foam catalyst, as an accelerator for the syntheses of polysulfured rubber. It is also used as a strong base in the photochemical (couplers) and in the pharmaceutical (steroids) industries. It is essential for the preparation of alkyl nitriles from alkyl halides and 3′-alkylthymidines from 3′-nitrothymidines. It serves as an efficient and selective catalyst for the benzoylation of alcohols. It replaces the expensive bases 1,8-Diazabicyclo[5.4.0]undec-7-ene (DBU) and 1,5-Diazabicyclo[4.3.0]non-5-ene (DBN) in organic synthesis.

Solubility
Miscible with water.

Notes
Air sensitive. Incompatible with strong oxidizing agents, mineral and organic acids, carbon dioxide. Keep away from sources of ignition.
RUO – Research Use Only

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