Thermo Scientific Chemicals

Tetrachlorophthalic anhydride, 98%, Thermo Scientific Chemicals

Catalog number: A17404.36
500 g, Each
Thermo Scientific Chemicals

Tetrachlorophthalic anhydride, 98%, Thermo Scientific Chemicals

Catalog number: A17404.36
500 g, Each
Quantity
Catalog number: A17404.36
also known as A17404-36
Price (USD)
Price: 52.60
Online price: 44.65
Your price:
Quantity
-

Chemical Identifiers

CAS
117-08-8
IUPAC Name
tetrachloro-1,3-dihydro-2-benzofuran-1,3-dione
Molecular Formula
C8Cl4O3
InChI Key
AUHHYELHRWCWEZ-UHFFFAOYSA-N
SMILES
ClC1=C2C(=O)OC(=O)C2=C(Cl)C(Cl)=C1Cl
Appearance (Color)
White
Form
crystalline powder
Assay (GC)
>97.5%
Assay (Aqueous acid-base Titration)
>97.5%

Description

Protection of amines as their tetrachlorophthalimide derivatives, by reaction with the anhydride in the presence of triethylamine, has been found to be useful in oligosaccharide chemistry. The group is stable to a wide range of reagents but can be selectively cleaved with ethylenediamine at lower temperatures than for the parent phthalimide derivatives; in particular, carboxylic esters are not cleaved under these conditions.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Protection of amines as their tetrachlorophthalimide derivatives, by reaction with the anhydride in the presence of triethylamine, has been found to be useful in oligosaccharide chemistry. The group is stable to a wide range of reagents but can be selectively cleaved with ethylenediamine at lower temperatures than for the parent phthalimide derivatives; in particular, carboxylic esters are not cleaved under these conditions.

Solubility
Hydrolyzes slowly in water.

Notes
Hygroscopic. Store away from oxidizing agents, acids.
WARNING: Cancer and Reproductive Harm – www.P65Warnings.ca.gov
RUO – Research Use Only

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