Thermo Scientific Chemicals

5-Methoxy-2-methylindole, 99+%, Thermo Scientific Chemicals

Catalog number: B21348.06
5 g, Each
Thermo Scientific Chemicals

5-Methoxy-2-methylindole, 99+%, Thermo Scientific Chemicals

Catalog number: B21348.06
5 g, Each
Quantity
Catalog number: B21348.06
also known as B21348-06
Price (USD)
Price: 116.00
Online price: 99.65
Your price:
Quantity
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Chemical Identifiers

CAS
1076-74-0
IUPAC Name
5-methoxy-2-methyl-1H-indole
Molecular Formula
C10H11NO
InChI Key
VSWGLJOQFUMFOQ-UHFFFAOYSA-N
SMILES
COC1=CC=C2NC(C)=CC2=C1
Appearance (Color)
White to cream to pale brown
Form
Crystals or powder or crystalline powder
Assay (GC)
≥99.0%
Melting Point (clear melt)
84.0-90.0?C

Description

It is employed as a reactant in preparation of indolylquinoxalines by condensation reactions, reactant in preparation of alkylindoles via Ir-catalyzed reductive alkylation, reactant in arylation reactions using a palladium acetate catalyst, reactant in enantioselective Friedel-Crafts alkylation and reactant in stereoselective synthesis of cyclopentaindolones via stereoselective [3+2] cyclopentannulation. As an indole derivative shown to be an effective inhibitor of the chlorinating activity of myeloperoxidase (MPO). Used in the metabolic synthesis of arylacetic acid anti-inflammatory synthesis.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
It is employed as a reactant in preparation of indolylquinoxalines by condensation reactions, reactant in preparation of alkylindoles via Ir-catalyzed reductive alkylation, reactant in arylation reactions using a palladium acetate catalyst, reactant in enantioselective Friedel-Crafts alkylation and reactant in stereoselective synthesis of cyclopentaindolones via stereoselective [3+2] cyclopentannulation. As an indole derivative shown to be an effective inhibitor of the chlorinating activity of myeloperoxidase (MPO). Used in the metabolic synthesis of arylacetic acid anti-inflammatory synthesis.

Solubility
Soluble in methanol (very faint turbidity.)

Notes
Store away from oxidizing agents. Keep the container tightly closed and place it in a cool, dry and well ventilated condition.
RUO – Research Use Only

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