Your search for "tmem173" returned 50 TaqMan® SNP Genotyping Assays
transmembrane protein 173
This gene encodes a five transmembrane protein that functions as a major regulator of the innate immune response to viral and bacterial infections. The encoded protein is a pattern recognition receptor that detects cytosolic nucleic acids and transmits signals that activate type I interferon responses. The encoded protein has also been shown to play a role in apoptotic signaling by associating with type II major histocompatibility complex. Mutations in this gene are the cause of infantile-onset STING-associated vasculopathy. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2014]
2610307O08RIK, ERIS, HMITA, HSTING, MITA, MPYS, NET23, RGD1562552, SAVI, STING, TMEM173
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