Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Immunogen sequence: MSVGAMKKG VGRAVGLGGG SGCQATEEDP LPDCGACAPG QGGRRWRLPQ PAWVEGSSAR LWEQATGTGW MDLEASLLPT GPNASNTSDG PDNLTSAGSP PRTGSISYIN IIMPSVFGTI CLLGIIGNST VIFAVVKKSK LHWCNNVPDI FIINLSVVDL LFLLGMPFMI HQLMGNGVWH FGETMCTLIT AMDANSQFTS TYILTAMAID RYLAT (1-214 aa encoded by BC001736)
MCHR1 is a member of the G protein-coupled receptor family 1. It is an integral plasma membrane protein which binds melanin-concentrating hormone. The encoded protein can inhibit cAMP accumulation and stimulate intracellular calcium flux, and is probably involved in the neuronal regulation of food consumption. Although structurally similar to somatostatin receptors, this protein does not seem to bind somatostatin.
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