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|Tested species reactivity||Human, Mouse, Rat|
|Host / Isotype||Rabbit / IgG|
|Immunogen||A synthetic peptide derived from the internal region of human ARHGEF12|
|Purification||Antigen affinity chromatography|
|Storage buffer||Dulbecco's PBS, pH 7.4, with 50% glycerol, 150mM NaCl|
|Contains||0.02% sodium azide|
|Tested Applications||Dilution *|
|Western Blot (WB)||1:500-1:1000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli working through G protein-coupled receptors. The encoded protein may form a complex with G proteins and stimulate Rho-dependent signals. This protein has been observed to form a myeloid/lymphoid fusion partner in acute myeloid leukemia. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2014].
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
KIAA0382; LARG; leukemia-associated rho guanine nucleotide exchange factor; leukemia-associated Rho guanine-nucleotide exchange factor; leukemia-associated RhoGEF; Rho guanine nucleotide exchange factor (GEF) 12; rho guanine nucleotide exchange factor 12
2310014B11Rik; ARHGEF12; AU019857; KIAA0382; LARG; mKIAA0382; PRO2792