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Proteintech
ARL13B Monoclonal Antibody (1H6C3)
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
66739-1-IG
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Dog,
Human,
Mouse,
Pig
Host/Isotype
Mouse
/ IgG2a
Class
Monoclonal
Type
Antibody
Clone
1H6C3
Immunogen
ARL13B Fusion Protein Ag12031 (1-321 aa encoded by BC094725)
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
1 mg/mL
Amount
150 µg
Purification
Protein A
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MFSLMASCC GWFKRWREPV RLANKQDKEG ALGEADVIEC LSLEKLVNEH KCLCQIEPCS AISGYGKKID KSIKKGLYWL LHVIARDFDA LNERIQKETT EQRALEEQEK QERAERVRKL REERKQNEQE QAELDGTSGL AELDPEPTNP FQPIASVIIE NEGKLEREKK NQKMEKDSDG CHLKHKMEHE QIETQGQVNH NGQKNNEFGL VENYKEALTQ QLKNEDETDR PSLESANGKK KTKKLRMKRN HRVEPLNIDD CAPESPTPPP PPPPVGWGTP KVTRLPKLEP LGETHHNDFY RKPLPPLAVP QRPNSDAHDV IS (1-321 aa encoded by BC094725)
Target Information
This gene encodes a member of the ADP-ribosylation factor-like family. The encoded protein is a small GTPase that contains both N-terminal and C-terminal guanine nucleotide-binding motifs. This protein is localized in the cilia and plays a role in cilia formation and in maintenance of cilia. Mutations in this gene are the cause of Joubert syndrome 8. Alternate splicing results in multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: ADP ribosylation factor like GTPase 13B; ADP-ribosylation factor-like 2-like 1; ARL2-like protein 1; protein hennin; unnamed protein product
Gene Aliases: A530097K21Rik; A930014M17Rik; ARL2L1; C530009C10Rik; hnn; JBTS8
UniProt ID: (Human) Q3SXY8, (Mouse) Q640N2
Entrez Gene ID: (Dog) 487934, (Pig) 100624385, (Human) 200894, (Mouse) 68146
kidney development
heart looping
smoothened signaling pathway
determination of left/right symmetry
dorsal/ventral pattern formation
neural tube patterning
interneuron migration from the subpallium to the cortex
formation of radial glial scaffolds
cilium morphogenesis
left/right axis specification
receptor localization to nonmotile primary cilium
non-motile cilium assembly
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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