PA5-29898 targets Alcohol dehydrogenase 1B in WB applications and shows reactivity with Human samples.
The PA5-29898 immunogen is recombinant fragment corresponding to a region within amino acids 125 and 375 of Human Alcohol dehydrogenase 1B.
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The protein encoded by this gene is a member of the alcohol dehydrogenase family. Members of this enzyme family metabolize a wide variety of substrates, including ethanol, retinol, other aliphatic alcohols, hydroxysteroids, and lipid peroxidation products. This encoded protein, consisting of several homo- and heterodimers of alpha, beta, and gamma subunits, exhibits high activity for ethanol oxidation and plays a major role in ethanol catabolism. Three genes encoding alpha, beta and gamma subunits are tandemly organized in a genomic segment as a gene cluster.
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Protein Aliases: ADH; ADH, beta subunit; Alcohol dehydrogenase 1B; alcohol dehydrogenase 2 (class I); alcohol dehydrogenase 2 (class I), beta polypeptide; Alcohol dehydrogenase subunit beta; aldehyde reductase; beta polypeptide; beta subunit; epididymis secretory protein Li 117
Gene Aliases: ADH1B; ADH2; HEL-S-117
UniProt ID: (Human) P00325
Entrez Gene ID: (Human) 125