|Immunohistochemistry (Paraffin) (IHC (P))||1:100-1:1000|
|Western Blot (WB)||1:500-1:3000|
|Western Blot (WB)||See 1 publications below|
|Tested Species reactivity||Human|
|Published species reactivity||Human Mouse|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Recombinant protein fragment corresponding to a region within amino acids 1 and 124 of Human Amphiregulin|
|Purification||Antigen affinity chromatography|
|Storage buffer||PBS, pH 7, with 1% BSA, 20% glycerol|
|Contains||0.025% Proclin 300|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
PA5-27298 targets Amphiregulin in IHC (P) and WB applications and shows reactivity with Human samples.
The PA5-27298 immunogen is recombinant protein fragment corresponding to a region within amino acids 1 and 124 of Human Amphiregulin.
The protein encoded by this gene is a member of the epidermal growth factor family. It is an autocrine growth factor as well as a mitogen for astrocytes, Schwann cells, and fibroblasts. It is related to epidermal growth factor (EGF) and transforming growth factor alpha (TGF-alpha). This protein interacts with the EGF/TGF-alpha receptor to promote the growth of normal epithelial cells and inhibits the growth of certain aggressive carcinoma cell lines. This encoded protein is associated with a psoriasis-like skin phenotype.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Amphiregulin; amphiregulin B; AR; AREGB; Colorectum cell-derived growth factor; CRDGF; schwannoma-derived growth factor
Gene Aliases: AR; AREG; AREGB; CRDGF; SDGF
UniProt ID: (Human) P15514
Entrez Gene ID: (Human) 374
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