This Antibody was verified by KnockOut to ensure that the antibody binds to the antigen stated. View Details
PA5-27315 targets Annexin A1 in IF, IHC (P), and WB applications and shows reactivity with Human, rat and mouse samples.
The PA5-27315 immunogen is recombinant fragment corresponding to a region within amino acids 24 and 346 of Human Annexin A1.
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.
Annexin I belongs to a family of Ca(2+)-dependent phospholipid binding proteins which have a molecular weight of approximately 35,000 to 40,000 and are preferentially located on the cytosolic face of the plasma membrane. Annexin I protein has an apparent relative molecular mass of 40 kDa, with phospholipase A2 inhibitory activity. Since phospholipase A2 is required for the biosynthesis of the potent mediators of inflammation, prostaglandins and leukotrienes, annexin I may have potential anti-inflammatory activity.
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Protein Aliases: Annexin 1 (p35) (Lipocortin 1); Annexin A1; Annexin I; annexin I (lipocortin I); Annexin-1; ANX1; Calpactin II; Calpactin-2; Chromobindin-9; lipocortin 1; Lipocortin I; LPC1; p35; Phospholipase A2 inhibitory protein
Gene Aliases: Anx-1; Anx-A1; ANX1; ANXA1; C430014K04Rik; Lpc-1; LPC1; p35