PA5-31479 targets Annexin A8 in IF, IHC (P), and WB applications and shows reactivity with Human samples.
The PA5-31479 immunogen is recombinant fragment corresponding to a region within amino acids 83 and 317 of Human Annexin A8.
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.
This gene encodes a member of the annexin family of evolutionarily conserved Ca2+ and phospholipid binding proteins. The encoded protein may function as an an anticoagulant that indirectly inhibits the thromboplastin-specific complex. Overexpression of this gene has been associated with acute myelocytic leukemia. A highly similar duplicated copy of this gene is found in close proximity on the long arm of chromosome 10.
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Protein Aliases: Annexin A8; Annexin VIII; Annexin-8; ANX8; VAC-beta; Vascular anticoagulant-beta
Gene Aliases: ANX8; ANXA8; CH17-360D5.2
UniProt ID: (Human) P13928
Entrez Gene ID: (Human) 653145