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Search Thermo Fisher Scientific
Applications | Tested Dilution | Publications |
---|---|---|
Western Blot (WB) |
1:500-1:2,000 | - |
Immunohistochemistry (Paraffin) (IHC (P)) |
1:100-1:200 | - |
Immunocytochemistry (ICC/IF) |
1:50-1:200 | - |
Product Specifications | |
---|---|
Species Reactivity |
Human, Mouse, Rat |
Host/Isotype |
Rabbit / IgG |
Class |
Polyclonal |
Type |
Antibody |
Immunogen |
A synthetic peptide corresponding to a sequence within amino acids 1-99 of human APOC3 |
Conjugate |
Unconjugated |
Form |
Liquid |
Concentration |
2.51 mg/mL |
Purification |
Affinity chromatography |
Storage buffer |
PBS, pH 7.3, with 50% glycerol |
Contains |
0.05% ProClin 300 |
Storage conditions |
-20° C, Avoid Freeze/Thaw Cycles |
RRID |
AB_2901203 |
Positive Samples: LO2, HT-29, mouse liver, mouse small intestine, rat small intestine
Apolipoprotein C-III, also known as apo-CIII, is a protein that in humans is encoded by the APOC3 gene. Apo-CIII is a component of very low density lipoprotein (VLDL). APOC3 inhibits lipoprotein lipase and hepatic lipase; it is thought to delay catabolism of triglyceride-rich particles. The APOA1, APOC3 and APOA4 genes are closely linked in both rat and human genomes. The A-I and A-IV genes are transcribed from the same strand, while the A-1 and C-III genes are convergently transcribed. An increase in apoC-III levels induces the development of hypertriglyceridemia.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Apo-CIII; apoC-III; Apolipoprotein; apolipoprotein C-3; Apolipoprotein C-III; Apolipoprotein C3; MGC150353
Gene Aliases: apo-CIII; ApoC-III; APOC3; APOCIII; HALP2
UniProt ID: (Human) P02656, (Mouse) P33622
Entrez Gene ID: (Human) 345, (Mouse) 11814, (Rat) 24207
Molecular Function:
apolipoprotein
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