Immunogen sequence: PFPLPLSSLF SDGGNVGCVD VIIQRAYPIQ WMEKTSSGLY IFRNEREEEK EAAKYVEAQQ KRLEALFTKI QEEFEEHEEN TTKPYLPSRA LTRQQVRALQ DGAELYEAVK NAADPAYLEG YFSEEQLRAL NNHRQMLNDK KQAQIQLEIR KAMESAEQKE QGLSRDVTTV WKLRIVSYSK KEKDSVILSI WRPSSDLYSL LTEGKRYRIY HLATSKSKSK SERANIQLAA TKKTQYQQLP VSDEILFQIY Q
Positive Samples: 293T; Cellular Location: Cytoplasm, Nucleus, centrosome, cytoskeleton, microtubule organizing center
Breast Cancer Type 2 susceptibility protein (BRCA2) is a tumor-suppressor protein reported to be involved in double-strand break repair, homologous recombination and S-phase checkpoint activation.
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Protein Aliases: brca 2; brca-2; breast cancer 2, mutation 1, University of Wisconsin-Madison; breast cancer susceptibility protein 2; Breast cancer type 2 susceptibility protein homolog; FANCB; Fanconi anemia group D1 protein homolog; RP11-298P3.4
Gene Aliases: Brca2; Fancd1; RAB163
UniProt ID: (Mouse) P97929
Molecular Function: damaged DNA-binding protein