This Antibody was verified by Relative expression to ensure that the antibody binds to the antigen stated. View Details
Immunogen sequence: KQTDTGSQKT HNVCASAPVH EIHESALRAK NRRQVEKRKL VAQRQRAHSV DVEKNRKMKA SSSENPWMTE YMRCYSARA
Highest antigen sequence identity to the following orthologs: Mouse - 85%, Rat - 86%.
Plays a role in microtubule (MT) stabilization and this stabilization involves the maintenance of NUMA1 at the spindle poles. Colocalizes with polyglutamylated MTs to promote MT stabilization and regulate bipolar spindle formation in mitosis. Binding of CCSAP to centrosomes and the spindle around centrosomes during mitosis inhibits MT depolymerization, thereby stabilizing the mitotic spindle (PubMed:26562023). May play a role in embryonic development. May be required for proper cilia beating. [UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: centriole and spindle-associated protein; Centriole, cilia and spindle-associated protein
Gene Aliases: C1orf96; CCSAP; CSAP
UniProt ID: (Human) Q6IQ19
Entrez Gene ID: (Human) 126731