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The antibody detects a significant 66 kDa* protein corresponding to the molecular mass of SCAI on SDS-PAGE immunoblots of mouse brain and human A431 cells. In brain, the antibody also detects 53 and 41 kDa bands.
This gene encodes a regulator of cell migration. The encoded protein appears to function in the RhoA (ras homolog gene family, member A)-Dia1 (diaphanous homolog 1) signal transduction pathway. Alternatively spliced transcript variants have been described.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Protein SCAI; suppressor of cancer cell invasion; Suppressor of cancer cell invasion protein
Gene Aliases: 9330112M16; A930041I02Rik; AI662729; C9orf126; NET40; SCAI
UniProt ID: (Human) Q8N9R8, (Mouse) Q8C8N2
Entrez Gene ID: (Human) 286205, (Rat) 690538, (Mouse) 320271
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