MA5-13631 targets p300/CBP (CREB-Binding Protein) in IF and IHC (P) applications and shows reactivity with Human, Mink, mouse, Non-human primate, and Rat samples.
The MA5-13631 immunogen is e1A affinity purified p300 protein.
p300 is a transcriptional adapter protein which is characterized by three cysteine- and histidine-rich regions and its C-terminus specifically binds the adenovirus E1A protein. p300, and p300-associated proteins, are components of TATA-binding protein (TBP) complexes. Protein kinase A mediated CREB phosphorylation results in the binding of CREB to a 265kDa nuclear protein designated CBP (for CREB-binding protein). CBP and p300 are homologous to each other.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: CREB-binding protein
Gene Aliases: AW558298; CBP; CBP/p300; CREBBP; KAT3A; p300/CBP; RSTS; RTS
UniProt ID: (Human) Q92793