Increased TNF-α Initiates Cytoplasmic Vacuolization in Whole Blood Coculture with Dengue Virus.
Journal of immunology research
Satria RD,Huang TW,Jhan MK,Shen TJ,Tseng PC,Wang YT,Yang ZY,Hsing CH,Lin CF
17-0149-42 was used in Flow Cytometry to demonstrate the potential hematological damage caused by ex vivo DENV-induced TNF-α.
Mon Dec 06 00:00:00 EST 2021
Immunoresponsive Tissue-Engineered Oral Mucosal Equivalents Containing Macrophages.
Tissue engineering. Part C, Methods
Ollington B,Colley HE,Murdoch C
17-0149-42 was used in Flow Cytometry to show functional activity of MDM-OME and illustrate their usefulness for investigations aimed at monitoring the immune response of the oral mucosa to pathogens, biomaterials, and for tissue toxicity and anti-inflammatory drug delivery studies.
Sun Aug 01 00:00:00 EDT 2021
Tick extracellular vesicles enable arthropod feeding and promote distinct outcomes of bacterial infection.
Oliva Chávez AS,Wang X,Marnin L,Archer NK,Hammond HL,Carroll EEM,Shaw DK,Tully BG,Buskirk AD,Ford SL,Butler LR,Shahi P,Morozova K,Clement CC,Lawres L,Neal AJO,Mamoun CB,Mason KL,Hobbs BE,Scoles GA,Barry EM,Sonenshine DE,Pal U,Valenzuela JG,Sztein MB,Pasetti MF,Levin ML,Kotsyfakis M,Jay SM,Huntley JF,Miller LS,Santambrogio L,Pedra JHF
17-0149-42 was used in Flow Cytometry to study the role of tick extracellular vesicles in anthropod feeding.
Thu Jun 17 00:00:00 EDT 2021
Extracellular vesicles from monocyte/platelet aggregates modulate human atherosclerotic plaque reactivity.
Journal of extracellular vesicles
Oggero S,de Gaetano M,Marcone S,Fitzsimons S,Pinto AL,Ikramova D,Barry M,Burke D,Montero-Melendez T,Cooper D,Burgoyne T,Belton O,Norling LV,Brennan EP,Godson C,Perretti M
17-0149-42 was used in Flow Cytometry to provide evidence that EVs released by mixed aggregates of monocytes and platelets in response to TNF-α display pro-inflammatory actions on endothelial cells and atherosclerotic plaques.
Thu Apr 01 00:00:00 EDT 2021
In Vitro Expansion and Characterization of Mesenchymal Stromal Cells from Peritoneal Dialysis Effluent in a Human Protein Medium.
Stem cells international
Han B,Zhou L,Guan Q,da Roza G,Wang H,Du C
17-0149 was used in Flow cytometry/Cell sorting to show that upon expansion in a human protein medium, pMSCs shows a differential MSC marker expression profile from those of bone marrow or adipose tissue-derived MSCs and could maintain the multipotency.
Wed Sep 30 00:00:00 EDT 2020
Optimizing the Method of Cell Separation from Bile of Patients with Cholangiocarcinoma for Flow Cytometry.
Gastroenterology research and practice
Xia Y,Gao Y,Wang B,Zhang H,Zhang Q
17-0149 was used in Flow cytometry/Cell sorting to assess FACS performance of cells in bile after modification of factors that may affect cell vitality, in order to optimise the cell separation method in bile of patients with cholangiocarcinoma.
Wed Sep 30 00:00:00 EDT 2020
The long non-coding RNA Cancer Susceptibility 15 (CASC15) is induced by isocitrate dehydrogenase (IDH) mutations and maintains an immature phenotype in adult acute myeloid leukemia.
Grasedieck S,Ruess C,Krowiorz K,Lux S,Pochert N,Schwarzer A,Klusmann JH,Jongen-Lavrencic M,Herold T,Bullinger L,Pollack JR,Rouhi A,Kuchenbauer F
17-0149 was used in Flow cytometry/Cell sorting to sequence stranded, non-poly-A-enriched cDNA libraries that were prepared from healthy human donor bone marrow.
Tue Sep 01 00:00:00 EDT 2020
Targeting FTO Suppresses Cancer Stem Cell Maintenance and Immune Evasion.
Su R,Dong L,Li Y,Gao M,Han L,Wunderlich M,Deng X,Li H,Huang Y,Gao L,Li C,Zhao Z,Robinson S,Tan B,Qing Y,Qin X,Prince E,Xie J,Qin H,Li W,Shen C,Sun J,Kulkarni P,Weng H,Huang H,Chen Z,Zhang B,Wu X,Olsen MJ,Müschen M,Marcucci G,Salgia R,Li L,Fathi AT,Li Z,Mulloy JC,Wei M,Horne D,Chen J
17-0149-42 was used in Flow Cytometry to demonstrate if fat mass and obesity-associated protein plays critical roles in cancer stem cell self-renewal and immune evasion.
Mon Jul 13 00:00:00 EDT 2020
Engineering monocyte/macrophage-specific glucocerebrosidase expression in human hematopoietic stem cells using genome editing.
Scharenberg SG,Poletto E,Lucot KL,Colella P,Sheikali A,Montine TJ,Porteus MH,Gomez-Ospina N
17-0149 was used in Flow cytometry/Cell sorting to report an efficient CRISPR/Cas9-based approach that targets glucocerebrosidase expression cassettes with a monocyte/macrophage-specific element to the CCR5 safe-harbor locus in human hematopoietic stem and progenitor cells.
Fri Jul 03 00:00:00 EDT 2020
Differential expression and predictive value of monocyte scavenger receptor CD163 in populations with different tuberculosis infection statuses.
BMC infectious diseases
Liu Q,Ou Q,Chen H,Gao Y,Liu Y,Xu Y,Ruan Q,Zhang W,Shao L
17-0149 was used in Flow cytometry/Cell sorting to detect surface expression of CD14, CD16, and CD163 on monocytes.
Thu Nov 28 00:00:00 EST 2019
Toll-Interleukin 1 Receptor Domain-Containing Adaptor Protein 180L Single-Nucleotide Polymorphism Is Associated With Susceptibility to Recurrent Pneumococcal Lower Respiratory Tract Infections in Children.
Frontiers in immunology
Siebert JN,Hamann L,Verolet CM,Gameiro C,Grillet S,Siegrist CA,Posfay-Barbe KM
17-0149 was used in Flow cytometry/Cell sorting to asses whether a defect somewhere along this toll-like receptor signally pathways increases susceptibility to recurrent pneumococcal low respiratory tract infections.
Mon Sep 16 00:00:00 EDT 2019
Effects of leukemia inhibitory factor receptor on the adipogenic differentiation of human bone marrow mesenchymal stem cells.
Molecular medicine reports
Wang T,Yan R,Xu X,Yu H,Wu J,Yang Y,Li W
17-0149 was used in Flow cytometry/Cell sorting to show that Leukemia inhibitory factor receptor promoted adipogenic differentiation, whereas LIF may negatively regulate this process.
Sat Jun 01 00:00:00 EDT 2019
Small-Molecule Targeting of Oncogenic FTO Demethylase in Acute Myeloid Leukemia.
Huang Y,Su R,Sheng Y,Dong L,Dong Z,Xu H,Ni T,Zhang ZS,Zhang T,Li C,Han L,Zhu Z,Lian F,Wei J,Deng Q,Wang Y,Wunderlich M,Gao Z,Pan G,Zhong D,Zhou H,Zhang N,Gan J,Jiang H,Mulloy JC,Qian Z,Chen J,Yang CG
17-0149 was used in Flow cytometry/Cell sorting to show that FTO is a druggable target and that targeting FTO by small-molecule inhibitors holds potential to treat AML.
Mon Apr 15 00:00:00 EDT 2019
The impact of the rs8005161 polymorphism on G protein-coupled receptor GPR65 (TDAG8) pH-associated activation in intestinal inflammation.
Tcymbarevich IV,Eloranta JJ,Rossel JB,Obialo N,Spalinger M,Cosin-Roger J,Lang S,Kullak-Ublick GA,Wagner CA,Scharl M,Seuwen K,Ruiz PA,Rogler G,de Vallière C,Misselwitz B
17-0149 was used in Flow cytometry/Cell sorting to analyse the clinical and functional relevance of the GPR65 associated single nucleotide polymorphism (SNP) rs8005161.
Mon Jan 07 00:00:00 EST 2019
Efficient immunoaffinity chromatography of lymphocytes directly from whole blood.
Mohr F,Przibilla S,Leonhardt F,Stemberger C,Dreher S,Müller TR,Fräßle SP,Schmidt GP,Kiene ML,Stadler H,Busch DH
17-0149 was used in Flow cytometry/Cell sorting to show that defined lymphocytes can be rapidly purified by immunoaffinity chromatography starting directly from whole blood.
Tue Nov 13 00:00:00 EST 2018
Genetic and Epigenetic Perturbations by DNMT3A-R882 Mutants Impaired Apoptosis through Augmentation of PRDX2 in Myeloid Leukemia Cells.
Neoplasia (New York, N.Y.)
Bera R,Chiu MC,Huang YJ,Liang DC,Lee YS,Shih LY
17-0149 was used in Flow cytometry/Cell sorting to study the effects of DNMT3A-Arg882His/Cys (R882H/C) mutations in myeloid leukaemia cells.
Thu Nov 01 00:00:00 EDT 2018
Challenging PD-L1 expressing cytotoxic T cells as a predictor for response to immunotherapy in melanoma.
Brochez L,Meireson A,Chevolet I,Sundahl N,Ost P,Kruse V
17-0149 was used in Flow cytometry/Cell sorting to study the association of PD-L1-expressing cytotoxic T cells with an altered immune climate and a negative impact on disease outcome in melanoma patients independent of treatment.
Thu Jul 26 00:00:00 EDT 2018
Increased Plasmodium falciparum Parasitemia in Non-splenectomized Saimiri sciureus Monkeys Treated with Clodronate Liposomes.
Frontiers in cellular and infection microbiology
Cunha JA,Carvalho LJM,Bianco-Junior C,Andrade MCR,Pratt-Riccio LR,Riccio EKP,Pelajo-Machado M,da Silva IJ,Druilhe P,Daniel-Ribeiro CT
17-0149 was used in Flow cytometry/Cell sorting to investigate whether a reduction in the numbers of phagocytic cells improves the development of Plasmodium falciparum parasitemia in non-splenectomised Saimiri sciureus monkeys.
Tue Jun 26 00:00:00 EDT 2018
Monocyte NOTCH2 expression predicts IFN-β immunogenicity in multiple sclerosis patients.
Adriani M,Nytrova P,Mbogning C,Hässler S,Medek K,Jensen PEH,Creeke P,Warnke C,Ingenhoven K,Hemmer B,Sievers C,Lindberg Gasser RL,Fissolo N,Deisenhammer F,Bocskei Z,Mikol V,Fogdell-Hahn A,Kubala Havrdova E,Broët P,Dönnes P,Mauri C,Jury EC
17-0149 was used in Flow cytometry/Cell sorting to show that nADA development was driven by a proinflammatory environment that triggered activation of the NOTCH2 signalling pathway prior to first IFN-β administration.
Thu Jun 07 00:00:00 EDT 2018
Cellular stressors contribute to the expansion of hematopoietic clones of varying leukemic potential.
Wong TN,Miller CA,Jotte MRM,Bagegni N,Baty JD,Schmidt AP,Cashen AF,Duncavage EJ,Helton NM,Fiala M,Fulton RS,Heath SE,Janke M,Luber K,Westervelt P,Vij R,DiPersio JF,Welch JS,Graubert TA,Walter MJ,Ley TJ,Link DC
17-0149 was used in Flow cytometry/Cell sorting to suggest different hematopoietic stressors promote the expansion of long-lived clones, carrying specific mutations, whose leukemic potential depends on harboured mutations.
Wed Jan 31 00:00:00 EST 2018
Hepatocyte-derived exosomes promote T follicular regulatory cell expansion during hepatitis C virus infection.
Hepatology (Baltimore, Md.)
Cobb DA,Kim OK,Golden-Mason L,Rosen HR,Hahn YS
17-0149 was used in Flow cytometry/Cell sorting to examine the accumulation of Tfr cells in the liver compartment during chronic HCV infection and defined the cellular and molecular mechanisms underlying their expansion.
Mon Jan 01 00:00:00 EST 2018
KSRP specifies monocytic and granulocytic differentiation through regulating miR-129 biogenesis and RUNX1 expression.
Zhao H,Wang X,Yi P,Si Y,Tan P,He J,Yu S,Ren Y,Ma Y,Zhang J,Wang D,Wang F,Yu J
17-0149 was used in Flow cytometry/Cell sorting to elucidate how KH-Type Splicing Regulatory Protein, miR-129, and RUNX1 participate in a regulatory axis to control the outcome of myeloid differentiation.
Fri Nov 10 00:00:00 EST 2017
TTI-621 (SIRPαFc): A CD47-Blocking Innate Immune Checkpoint Inhibitor with Broad Antitumor Activity and Minimal Erythrocyte Binding.
Clinical cancer research : an official journal of the American Association for Cancer Research
Petrova PS,Viller NN,Wong M,Pang X,Lin GH,Dodge K,Chai V,Chen H,Lee V,House V,Vigo NT,Jin D,Mutukura T,Charbonneau M,Truong T,Viau S,Johnson LD,Linderoth E,Sievers EL,Maleki Vareki S,Figueredo R,Pampillo M,Koropatnick J,Trudel S,Mbong N,Jin L,Wang JC,Uger RA
17-0149 was used in Flow cytometry/Cell sorting to establish CD47 as a critical regulator of innate immune surveillance and form the basis for clinical development of TTI-621 in multiple oncology indications.
Wed Feb 15 00:00:00 EST 2017
Transendothelial migration of human umbilical mesenchymal stem cells across uterine endothelial monolayers: Junctional dynamics and putative mechanisms.
Ebrahim NA,Leach L
17-0149 was used in Flow cytometry/Cell sorting to study the transmigration of foetal stem cells across maternal endothelial barriers, and investigate whether they can subsequently influence maternal endothelial integrity.
Thu Dec 01 00:00:00 EST 2016
Quantitative Measurements of HIV-1 and Dextran Capture by Human Monocyte-derived Dendritic Cells (MDDCs).
Ménager MM,Littman DR
17-0149 was used in Flow cytometry/Cell sorting to develop a protocol for measuring and quantifying the amount of HIV-1 particles and dextran molecules internalised in human monocyte derived dendritic cells.
Sun Nov 20 00:00:00 EST 2016
LECT2 drives haematopoietic stem cell expansion and mobilization via regulating the macrophages and osteolineage cells.
Lu XJ,Chen Q,Rong YJ,Yang GJ,Li CH,Xu NY,Yu CH,Wang HY,Zhang S,Shi YH,Chen J
17-0149 was used in Flow cytometry/Cell sorting to investigate the mechanisms by which cytokines in the blood affect HSC homeostasis, showing that LECT2 drives HSC expansion and mobilisation.
Tue Sep 06 00:00:00 EDT 2016
TNFα promotes CAR-dependent migration of leukocytes across epithelial monolayers.
Morton PE,Hicks A,Ortiz-Zapater E,Raghavan S,Pike R,Noble A,Woodfin A,Jenkins G,Rayner E,Santis G,Parsons M
17-0149 was used in Flow cytometry/Cell sorting to demonstrate that trans-epithelial migration of monocyte-derived THP-1 cells is regulated by phosphorylation of the Coxsackie and Adenovirus receptor.
Thu May 19 00:00:00 EDT 2016
Retinoid X receptor activation reverses age-related deficiencies in myelin debris phagocytosis and remyelination.
Brain : a journal of neurology
Natrajan MS,de la Fuente AG,Crawford AH,Linehan E,Nuñez V,Johnson KR,Wu T,Fitzgerald DC,Ricote M,Bielekova B,Franklin RJ
17-0149 was used in Flow cytometry/Cell sorting to reveal the retinoid X receptor pathway as a regulator of myelin debris clearance and age-related decline in remyelination.
Tue Dec 01 00:00:00 EST 2015
Pioglitazone regulates myelin phagocytosis and multiple sclerosis monocytes.
Annals of clinical and translational neurology
Natrajan MS,Komori M,Kosa P,Johnson KR,Wu T,Franklin RJ,Bielekova B
17-0149 was used in Flow cytometry/Cell sorting to determine if monocyte function and differentiation differs in MS patients, and whether pioglitazone can reverse these differences to promote CNS recovery.
Tue Dec 01 00:00:00 EST 2015
DNA-Containing Immunocomplexes Promote Inflammasome Assembly and Release of Pyrogenic Cytokines by CD14+ CD16+ CD64high CD32low Inflammatory Monocytes from Malaria Patients.
Hirako IC,Gallego-Marin C,Ataide MA,Andrade WA,Gravina H,Rocha BC,de Oliveira RB,Pereira DB,Vinetz J,Diamond B,Ram S,Golenbock DT,Gazzinelli RT
17-0149 was used in Flow cytometry/Cell sorting to investigate the effect of DNA-containing immunocomplexes on monocytes in malaria patients.
Tue Nov 17 00:00:00 EST 2015
Interferon-γ enhances both the anti-bacterial and the pro-inflammatory response of human mast cells to Staphylococcus aureus.
Swindle EJ,Brown JM,Rådinger M,DeLeo FR,Metcalfe DD
17-0149 was used in Flow cytometry/Cell sorting to investigate the effect of interferon-γ on the biological responses of human mast cells to Staphylococcus aureus.
Sun Nov 01 00:00:00 EDT 2015
Control of signaling-mediated clearance of apoptotic cells by the tumor suppressor p53.
Science (New York, N.Y.)
Yoon KW,Byun S,Kwon E,Hwang SY,Chu K,Hiraki M,Jo SH,Weins A,Hakroush S,Cebulla A,Sykes DB,Greka A,Mundel P,Fisher DE,Mandinova A,Lee SW
17-0149 was used in Flow cytometry/Cell sorting to reveal that p53-induced expression of death domain 1α regulates the efficient clearance of dead cells and proper immune tolerance.
Fri Jul 31 00:00:00 EDT 2015
Peanut oral immunotherapy transiently expands circulating Ara h 2-specific B cells with a homologous repertoire in unrelated subjects.
The Journal of allergy and clinical immunology
Patil SU,Ogunniyi AO,Calatroni A,Tadigotla VR,Ruiter B,Ma A,Moon J,Love JC,Shreffler WG
17-0149 was used in Flow cytometry/Cell sorting to investigate the contribution of induced antibody clones to clinical tolerance in peanut oral immunotherapy (PNOIT), showing that PNOIT transiently expands circulating Ara h 2-specific B cells.
Wed Jul 01 00:00:00 EDT 2015
Characterization of the in vivo immune network of IDO, tryptophan metabolism, PD-L1, and CTLA-4 in circulating immune cells in melanoma.
Chevolet I,Speeckaert R,Schreuer M,Neyns B,Krysko O,Bachert C,Hennart B,Allorge D,van Geel N,Van Gele M,Brochez L
17-0149 was used in Flow cytometry/Cell sorting to demonstrate that the expression of IDO, PD-L1, and CTLA-4 in the peripheral blood of melanoma patients is strongly interconnected.
Sun Mar 01 00:00:00 EST 2015
Clinical significance of plasmacytoid dendritic cells and myeloid-derived suppressor cells in melanoma.
Journal of translational medicine
Chevolet I,Speeckaert R,Schreuer M,Neyns B,Krysko O,Bachert C,Van Gele M,van Geel N,Brochez L
17-0149 was used in Flow cytometry/Cell sorting to investigate multiple immune cell types in a series of blood samples from melanoma patients with different stages of the disease.
Fri Jan 16 00:00:00 EST 2015
Soluble tumor necrosis factor related apoptosis inducing ligand level as a predictor of severity of sepsis and the risk of mortality in septic patients.
Tian Y,Tao T,Zhu J,Zou Y,Wang J,Li J,Bo L,Deng X
17-0149 was used in Flow cytometry/Cell sorting to examine soluble TRAIL levels in septic patients to explore the association between sTRAIL level and the risk of mortality.
Sun Oct 12 00:00:00 EDT 2014
The CD14+CD16+ inflammatory monocyte subset displays increased mitochondrial activity and effector function during acute Plasmodium vivax malaria.
Antonelli LR,Leoratti FM,Costa PA,Rocha BC,Diniz SQ,Tada MS,Pereira DB,Teixeira-Carvalho A,Golenbock DT,Gonçalves R,Gazzinelli RT
17-0149 was used in Flow cytometry/Cell sorting to study inflammatory monocyte subsets displaying increased mitochondrial activity and effector function during malaria.
Mon Sep 01 00:00:00 EDT 2014
MicroRNAs transfer from human macrophages to hepato-carcinoma cells and inhibit proliferation.
Journal of immunology (Baltimore, Md. : 1950)
Aucher A,Rudnicka D,Davis DM
17-0149 was used in Flow cytometry/Cell sorting to investigate the function of nucleic acid transfer between human cells, showing that microRNAs transfer from human macrophages to hepato-carcinoma cells and inhibit proliferation.
Sun Dec 15 00:00:00 EST 2013
Tumor necrosis factor receptor 1 associates with CD137 ligand and mediates its reverse signaling.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Moh MC,Lorenzini PA,Gullo C,Schwarz H
17-0149 was used in Flow cytometry/Cell sorting to determine the mechanisms behind the activation of monocytes by reverse signalling through the CD137 ligand.
Thu Aug 01 00:00:00 EDT 2013
Neutrophil paralysis in Plasmodium vivax malaria.
PLoS neglected tropical diseases
Leoratti FM,Trevelin SC,Cunha FQ,Rocha BC,Costa PA,Gravina HD,Tada MS,Pereira DB,Golenbock DT,Antonelli LR,Gazzinelli RT
17-0149 was used in Flow cytometry/Cell sorting to investigate the activation and function of neutrophils during acute episodes of Plasmodium vivax malaria.
Fri Sep 28 00:00:00 EDT 2012
Actin polymerization stabilizes α4β1 integrin anchors that mediate monocyte adhesion.
The Journal of cell biology
Rullo J,Becker H,Hyduk SJ,Wong JC,Digby G,Arora PD,Cano AP,Hartwig J,McCulloch CA,Cybulsky MI
17-0149 was used in Flow cytometry/Cell sorting to reveal that force triggers actin polymerisation at upstream 41 integrin adhesion sites and the adjacent cortical cytoskeleton.
Mon Apr 02 00:00:00 EDT 2012
The cell surface proteome of human mesenchymal stromal cells.
Niehage C,Steenblock C,Pursche T,Bornhäuser M,Corbeil D,Hoflack B
17-0149 was used in Flow cytometry/Cell sorting to obtain a comprehensive view of the cell surface proteome of bone marrow-derived human mesenchymal stromal cells (hMSCs).
Thu Sep 29 00:00:00 EDT 2011
Modulation of dendritic cell maturation and function by the Tax protein of human T cell leukemia virus type 1.
Journal of leukocyte biology
Jain P,Ahuja J,Khan ZK,Shimizu S,Meucci O,Jennings SR,Wigdahl B
17-0149 was used in Flow cytometry/Cell sorting to demonstrate extracellular Tax to induce maturation and functional alterations in human monocyte-derived dendritic cells.
Sun Jul 01 00:00:00 EDT 2007