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|Tested species reactivity||Human, Mouse|
|Published species reactivity||Rat, Mouse|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic peptide corresponding to C-terminus of mouse CD31|
|Storage buffer||tissue culture supernatant diluted in TBS, pH 7.5, with 1% BSA|
|Contains||<0.1% sodium azide|
|Storage Conditions||4° C, do not freeze|
|Tested Applications||Dilution *|
|Immunohistochemistry (Paraffin) (IHC (P))||1:50|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
|Immunohistochemistry (IHC)||See 7 publications below|
Heat-mediated antigen retrieval is recommended prior to staining, using a 10mM citrate buffer, pH 6.0, for 10 minutes followed by cooling at room temperature for 20 min. Following antigen retrieval, incubate samples with primary antibody for 10 min at room temperature. A suggested positive control is tonsil tissue.
CD31 is a glycoprotein expressed on endothelial cells and in platelets. It is known to be involved in cell signaling and cell adhesion
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Spirulina improves non-alcoholic steatohepatitis, visceral fat macrophage aggregation, and serum leptin in a mouse model of metabolic syndrome.
MA5-16337 was used in immunohistochemistry to study the beneficial effects of spirulina on macrophages and metabolic parameters in a murine model of metabolic syndrome
|Fujimoto M,Tsuneyama K,Fujimoto T,Selmi C,Gershwin ME,Shimada Y||Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver (44:767)||2012|
Hyperglycemia limits experimental aortic aneurysm progression.
MA5-16337 was used in immunohistochemistry to study the effect of hyperglycemia on the progression of experimental aortic aneurysm
|Miyama N,Dua MM,Yeung JJ,Schultz GM,Asagami T,Sho E,Sho M,Dalman RL||Journal of vascular surgery (52:975)||2010|
Eukaryotic expression of extracellular ligand binding domains of murine Tie-2 and its anti-angiogenesis effect in SGC-7901 cell lines.
MA5-16337 was used in immunohistochemistry to study the anti-angiogenic effects on a gastric cancer cell line of the recombinantly expressed extracellular ligand binding domains of murine Tie-2
|Yang H,Yang K,Hu JK,Tang H,Zhang B,Chen ZX,Wang YJ,Chen JP||Journal of gastroenterology and hepatology (25:345)||2010|
Correlation between scaffold in vivo biocompatibility and in vitro cell compatibility using mesenchymal and mononuclear cell cultures.
MA5-16337 was used in immunohistochemistry to comapre silk and polyglycolic acid scaffold biocompatibility using mesenchymal and mononuclear cell cultures
|Seo YK,Yoon HH,Park YS,Song KY,Lee WS,Park JK||Cell biology and toxicology (25:513)||2009|
Sorafenib and rapamycin induce growth suppression in mouse models of hepatocellular carcinoma.
MA5-16337 was used in immunohistochemistry to study the antitumour activity and mechanisms of action of sorafenib against hepatocellular carcinoma xenografts
|Huynh H,Ngo VC,Koong HN,Poon D,Choo SP,Thng CH,Chow P,Ong HS,Chung A,Soo KC||Journal of cellular and molecular medicine (13:2673)||2009|
Brivanib alaninate, a dual inhibitor of vascular endothelial growth factor receptor and fibroblast growth factor receptor tyrosine kinases, induces growth inhibition in mouse models of human hepatocellular carcinoma.
MA5-16337 was used in immunohistochemistry to study the ability of a dual inhibitor of VEGF receptor and FGF receptor tyrosine kinases to inhibit growth in hepatocellular carcinoma
|Huynh H,Ngo VC,Fargnoli J,Ayers M,Soo KC,Koong HN,Thng CH,Ong HS,Chung A,Chow P,Pollock P,Byron S,Tran E||Clinical cancer research : an official journal of the American Association for Cancer Research (14:6146)||2008|
A central role for hepatocyte growth factor in adipose tissue angiogenesis.
MA5-16337 was used in immunohistochemistry to study adipose tissue angiogenesis and the role of HGF
|Bell LN,Cai L,Johnstone BH,Traktuev DO,March KL,Considine RV||American journal of physiology. Endocrinology and metabolism (294:E336)||2008|
adhesion molecule; CD31 antigen; CD31/EndoCAM; endoCAM; platelet endothelial cell adhesion molecule; platelet/endothelial cell adhesion molecule 1
C85791; CD31; CD31/EndoCAM; endoCAM; GPIIA'; PECA1; Pecam; PECAM-1; PECAM1