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Staining of normal human peripheral blood cells with Anti-Human CD19 FITC followed by intracellular staining with Mouse IgG1 K Isotype Control PerCP-Cyanine5.5 (top) or Anti-CD79a PerCP-Cyanine5.5 (bottom, A16424) using IC Fixation and Permeabilization Buffers. Cells in the lymphocyte gate were used for analysis.
|Tested species reactivity||Rat , Human , Mouse|
|Host / Isotype||Mouse / IgG1, kappa|
|Storage buffer||proprietary buffer|
|Contains||0.09% sodium azide|
|Storage Conditions||4° C|
|Tested Applications||Dilution *|
|Flow Cytometry (Flow)||Assay Dependent|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
A disulphide-linked heterodimer, consisting of mb-1 (or CD79a) and B29 (or CD79b) polypeptides, is non-covalently associated with membrane-bound immunoglobulins on B cells to constitute the B cell Ag receptor. CD79a first appears at pre B cell stage and persists until the plasma cell stage where it is found as an intracellular component. CD79a is found in the majority of acute leukemias of precursor B cell type, in B cell lines, B cell lymphomas, and in some myelomas. It is not present in myeloid or T cell lines.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Iga, mb-1, Ly-54, MB-1, Ig-alpha, IGA, Ly54, Igalpha
B-cell antigen receptor complex-associated protein alpha chain, CD79a antigen (immunoglobulin-associated alpha), MB-1 membrane glycoprotein, ig-alpha, membrane-bound immunoglobulin-associated protein, surface IgM-associated protein, Ig alpha, immunoglobulin-associated alpha