Product References
6-Shogaol Ameliorates Liver Inflammation and Fibrosis in Mice on a Methionine- and Choline-Deficient Diet by Inhibiting Oxidative Stress, Cell Death, and Endoplasmic Reticulum Stress.
Molecules (Basel, Switzerland)
Yang AY,Kim K,Kwon HH,Leem J,Song JE
Published figure using CHOP monoclonal antibody (Product # MA1-250) in Immunohistochemistry
Mon Jan 15 00:00:00 UTC 2024
6-Shogaol Ameliorates Liver Inflammation and Fibrosis in Mice on a Methionine- and Choline-Deficient Diet by Inhibiting Oxidative Stress, Cell Death, and Endoplasmic Reticulum Stress.
Molecules (Basel, Switzerland)
Yang AY,Kim K,Kwon HH,Leem J,Song JE
Published figure using CHOP monoclonal antibody (Product # MA1-250) in Immunohistochemistry
Mon Jan 15 00:00:00 UTC 2024
Early activation of cellular stress and death pathways caused by cytoplasmic TDP-43 in the rNLS8 mouse model of ALS and FTD.
Molecular psychiatry
Luan W,Wright AL,Brown-Wright H,Le S,San Gil R,Madrid San Martin L,Ling K,Jafar-Nejad P,Rigo F,Walker AK
MA1-250 was used in Western Blot to suggest that precise temporal modulation of cell stress and death pathways may be beneficial to protect against neurodegeneration in ALS and FTD.
Thu Jun 01 00:00:00 UTC 2023
Molecular Mechanisms of the Cytotoxic Effect of Recombinant Selenoprotein SELENOM on Human Glioblastoma Cells.
International journal of molecular sciences
Rogachev VV,Goltyaev MV,Varlamova EG,Turovsky EA
MA1-250 was used in Western Blot to demonstrate a dose-dependent depletion of the Ca2+ pool under the action of SELENOM, which proves the important role of this protein in the regulation of calcium homeostasis in the cell.
Thu Mar 30 00:00:00 UTC 2023
A cytosolic surveillance mechanism activates the mitochondrial UPR.
Nature
Sutandy FXR,Gößner I,Tascher G,Münch C
Published figure using CHOP monoclonal antibody (Product # MA1-250) in Western Blot
Thu Jun 01 00:00:00 UTC 2023
A cytosolic surveillance mechanism activates the mitochondrial UPR.
Nature
Sutandy FXR,Gößner I,Tascher G,Münch C
Published figure using CHOP monoclonal antibody (Product # MA1-250) in Western Blot
Thu Jun 01 00:00:00 UTC 2023
A localized hydrogel-mediated chemotherapy causes immunogenic cell death via activation of ceramide-mediated unfolded protein response.
Science advances
Kar A,Jain D,Kumar S,Rajput K,Pal S,Rana K,Kar R,Jha SK,Medatwal N,Yavvari PS,Pandey N,Mehta D,Sharma H,Bhattacharya D,Pradhan MK,Sharma RD,Srivastava A,Agrawal U,Mukhopadhyay A,Sengupta S,Patil VS,Bajaj A,Dasgupta U
Published figure using CHOP monoclonal antibody (Product # MA1-250) in Western Blot
Fri Jun 30 00:00:00 UTC 2023
Ursodeoxycholic Acid Binds PERK and Ameliorates Neurite Atrophy in a Cellular Model of GM2 Gangliosidosis.
International journal of molecular sciences
Morales C,Fernandez M,Ferrer R,Raimunda D,Carrer DC,Bollo M
MA1-250 was used in Immunocytochemistry to suggest a direct interaction between UDCA and the cytosolic domain of PERK, which promotes kinase phosphorylation and dimerization.
Thu Apr 13 00:00:00 UTC 2023
Intracellular remodeling associated with endoplasmic reticulum stress modifies biomechanical compliance of bladder cells.
Cell communication and signaling : CCS
Gruber L,Jobst M,Kiss E,Karasová M,Englinger B,Berger W,Del Favero G
MA1-250 was used in Immunocytochemistry to study role of endoplasmic reticulum (ER) in the maintenance of cell mechanical stability is less investigated by treating T24 bladder cancer cells with the ER stress inducers brefeldin A (10-40nM BFA, 24 h) and thapsigargin (0.1-100nM TG, 24 h).
Mon Oct 30 00:00:00 UTC 2023
ELOVL2 promotes cancer progression by inhibiting cell apoptosis in renal cell carcinoma.
Oncology reports
Tanaka K,Kandori S,Sakka S,Nitta S,Tanuma K,Shiga M,Nagumo Y,Negoro H,Kojima T,Mathis BJ,Shimazui T,Watanabe M,Sato TA,Miyamoto T,Matsuzaka T,Shimano H,Nishiyama H
Published figure using CHOP monoclonal antibody (Product # MA1-250) in Western Blot
Tue Feb 01 00:00:00 UTC 2022
ELOVL2 promotes cancer progression by inhibiting cell apoptosis in renal cell carcinoma.
Oncology reports
Tanaka K,Kandori S,Sakka S,Nitta S,Tanuma K,Shiga M,Nagumo Y,Negoro H,Kojima T,Mathis BJ,Shimazui T,Watanabe M,Sato TA,Miyamoto T,Matsuzaka T,Shimano H,Nishiyama H
Published figure using CHOP monoclonal antibody (Product # MA1-250) in Western Blot
Tue Feb 01 00:00:00 UTC 2022
Exposure to binge ethanol and fatty acid ethyl esters exacerbates chronic ethanol-induced pancreatic injury in hepatic alcohol dehydrogenase-deficient deer mice.
American journal of physiology. Gastrointestinal and liver physiology
Srinivasan MP,Bhopale KK,Caracheo AA,Kaphalia L,Gong B,Popov VL,Boor PJ,Shakeel Ansari GA,Kaphalia BS
MA1-250 was used in Western Blotting to evaluate differential pancreatic injury in hepatic alcohol dehydrogenase-deficient (ADH-) deer mice fed chronic ethanol (EtOH), chronic plus binge EtOH, and chronic plus binge EtOH and fatty acid ethyl esters (FAEEs, nonoxidative metabolites of EtOH) to understand the metabolic basis of ACP.
Tue Mar 01 00:00:00 UTC 2022
A chemical genomics-aggrephagy integrated method studying functional analysis of autophagy inducers.
Autophagy
Kataura T,Tashiro E,Nishikawa S,Shibahara K,Muraoka Y,Miura M,Sakai S,Katoh N,Totsuka M,Onodera M,Shin-Ya K,Miyamoto K,Sasazawa Y,Hattori N,Saiki S,Imoto M
Published figure using CHOP monoclonal antibody (Product # MA1-250) in Western Blot
Sun Aug 01 00:00:00 UTC 2021
A chemical genomics-aggrephagy integrated method studying functional analysis of autophagy inducers.
Autophagy
Kataura T,Tashiro E,Nishikawa S,Shibahara K,Muraoka Y,Miura M,Sakai S,Katoh N,Totsuka M,Onodera M,Shin-Ya K,Miyamoto K,Sasazawa Y,Hattori N,Saiki S,Imoto M
Published figure using CHOP monoclonal antibody (Product # MA1-250) in Western Blot
Sun Aug 01 00:00:00 UTC 2021
Soat1 mediates the mouse strain effects on cholesterol loading-induced endoplasmic reticulum stress and CHOP expression in macrophages.
Biochimica et biophysica acta. Molecular and cell biology of lipids
Luo M,Opoku E,Traughber CA,Hai Q,Robinet P,Berisha S,Smith JD
MA1-250 was used in Western Blot to investigate the upstream pathway of free cholesterol induced endoplasmic reticulum stress.
Fri Jan 01 00:00:00 UTC 2021
Aging and Hypercholesterolemia Differentially Affect the Unfolded Protein Response in the Vasculature of ApoE-/- Mice.
Journal of the American Heart Association
Zhou Y,Wan X,Seidel K,Zhang M,Goodman JB,Seta F,Hamburg N,Han J
Published figure using CHOP monoclonal antibody (Product # MA1-250) in Immunohistochemistry
Tue Sep 21 00:00:00 UTC 2021
Exercise training mitigates ER stress and UCP2 deficiency-associated coronary vascular dysfunction in atherosclerosis.
Scientific reports
Hong J,Park E,Lee J,Lee Y,Rooney BV,Park Y
MA1-250 was used in Western Blot to unravel the mechanisms behind exercise-induced reduction of endoplasmic reticulum stress, uncoupling protein-2 activation and the enhancement of endothelial function.
Thu Jul 29 00:00:00 UTC 2021
Exercise training mitigates ER stress and UCP2 deficiency-associated coronary vascular dysfunction in atherosclerosis.
Scientific reports
Hong J,Park E,Lee J,Lee Y,Rooney BV,Park Y
MA1-250 was used in Western Blot to unravel the mechanisms behind exercise-induced reduction of endoplasmic reticulum stress, uncoupling protein-2 activation and the enhancement of endothelial function.
Thu Jul 29 00:00:00 UTC 2021
Intestinal Goblet Cell Loss during Chorioamnionitis in Fetal Lambs: Mechanistic Insights and Postnatal Implications.
International journal of molecular sciences
van Gorp C,de Lange IH,Massy KRI,Kessels L,Jobe AH,Cleutjens JPM,Kemp MW,Saito M,Usada H,Newnham J,Hütten M,Kramer BW,Zimmermann LJ,Wolfs TGAM
MA1-250 was used in Immunohistochemistry (Paraffin) to indicate that ER stress drives apoptosis of maturating goblet cells during chorioamnionitis, ultimately reducing goblet cell numbers.
Tue Feb 16 00:00:00 UTC 2021
Intestinal Goblet Cell Loss during Chorioamnionitis in Fetal Lambs: Mechanistic Insights and Postnatal Implications.
International journal of molecular sciences
van Gorp C,de Lange IH,Massy KRI,Kessels L,Jobe AH,Cleutjens JPM,Kemp MW,Saito M,Usada H,Newnham J,Hütten M,Kramer BW,Zimmermann LJ,Wolfs TGAM
MA1-250 was used in Immunohistochemistry (Paraffin) to indicate that ER stress drives apoptosis of maturating goblet cells during chorioamnionitis, ultimately reducing goblet cell numbers.
Tue Feb 16 00:00:00 UTC 2021
Progesterone receptor membrane component 1 reduces cardiac steatosis and lipotoxicity via activation of fatty acid oxidation and mitochondrial respiration.
Scientific reports
Lee SR,Heo JH,Jo SL,Kim G,Kim SJ,Yoo HJ,Lee KP,Kwun HJ,Shin HJ,Baek IJ,Hong EJ
Published figure using CHOP monoclonal antibody (Product # MA1-250) in Western Blot
Thu Apr 22 00:00:00 UTC 2021
ALG-2 and peflin regulate COPII targeting and secretion in response to calcium signaling.
The Journal of biological chemistry
Sargeant J,Seiler DK,Costain T,Madreiter-Sokolowski CT,Gordon DE,Peden AA,Malli R,Graier WF,Hay JC
MA1-250 was used in Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot to provide insights into how PEF protein dynamics affect secretion of important physiological cargoes such as collagen I and significantly impact ER stress.
Wed Dec 01 00:00:00 UTC 2021
Suppression of MEHMO Syndrome Mutation in eIF2 by Small Molecule ISRIB.
Molecular cell
Young-Baird SK,Lourenço MB,Elder MK,Klann E,Liebau S,Dever TE
MA1-250 was used in Western Blotting to show that a mutation at the C terminus of eIF2γ impairs CDC123 promotion of eIF2 complex formation and decreases the level of eIF2-GTP-Met-tRNAiMet ternary complexes, using patient-derived induced pluripotent stem cells.
Thu Feb 20 00:00:00 UTC 2020
Rhodopsin Genomic Loci DNA Nanoparticles Improve Expression and Rescue of Retinal Degeneration in a Model for Retinitis Pigmentosa.
Molecular therapy : the journal of the American Society of Gene Therapy
Zheng M,Mitra RN,Weiss ER,Han Z
MA1-250 was used in Western Blotting to demonstrate the transducing of the rhodopsin genomic locus using compacted DNA nanoparticles.
Wed Feb 05 00:00:00 UTC 2020
Fumarate and oxidative stress synergize to promote stability of C/EBP homologous protein in the adipocyte.
Free radical biology & medicine
Manuel AM,Walla MD,Dorn MT,Tanis RM,Piroli GG,Frizzell N
MA1-250 was used in Western Blotting to demonstrate that physiological increases in the metabolite fumarate during high glucose exposure contributes to the presence of oxidative stress and sustained CHOP levels in the adipocyte during diabetes.
Thu Feb 20 00:00:00 UTC 2020
Potentiation of rifampin activity in a mouse model of tuberculosis by activation of host transcription factor EB.
PLoS pathogens
Bryk R,Mundhra S,Jiang X,Wood M,Pfau D,Weber E,Park S,Zhang L,Wilson C,Van der Westhuyzen R,Street L,Chibale K,Zimmerman M,Dartois V,Pastore N,Ballabio A,Hawryluk N,Canan S,Khetani V,Camardo J,Nathan C
Published figure using CHOP monoclonal antibody (Product # MA1-250) in Western Blot
Mon Jun 01 00:00:00 UTC 2020
Potentiation of rifampin activity in a mouse model of tuberculosis by activation of host transcription factor EB.
PLoS pathogens
Bryk R,Mundhra S,Jiang X,Wood M,Pfau D,Weber E,Park S,Zhang L,Wilson C,Van der Westhuyzen R,Street L,Chibale K,Zimmerman M,Dartois V,Pastore N,Ballabio A,Hawryluk N,Canan S,Khetani V,Camardo J,Nathan C
Published figure using CHOP monoclonal antibody (Product # MA1-250) in Western Blot
Mon Jun 01 00:00:00 UTC 2020
Systemic hypoxia led to little retinal neuronal loss and dramatic optic nerve glial response.
Experimental eye research
Mesentier-Louro LA,Shariati MA,Dalal R,Camargo A,Kumar V,Shamskhou EA,de Jesus Perez V,Liao YJ
MA1-250 was used in Immunocytochemistry to support a model where glial dysfunction is among the earliest events in systemic hypoxia - suggesting that glia may be a novel target in treatment of hypoxia.
Wed Apr 01 00:00:00 UTC 2020
Protein Stability Buffers the Cost of Translation Attenuation following eIF2α Phosphorylation.
Cell reports
Schneider K,Nelson GM,Watson JL,Morf J,Dalglish M,Luh LM,Weber A,Bertolotti A
Published figure using CHOP monoclonal antibody (Product # MA1-250) in Western Blot
Tue Sep 15 00:00:00 UTC 2020
Protein Stability Buffers the Cost of Translation Attenuation following eIF2α Phosphorylation.
Cell reports
Schneider K,Nelson GM,Watson JL,Morf J,Dalglish M,Luh LM,Weber A,Bertolotti A
Published figure using CHOP monoclonal antibody (Product # MA1-250) in Western Blot
Tue Sep 15 00:00:00 UTC 2020
Interaction between goniothalamin and peroxisomal multifunctional enzyme type 2 triggering endoplasmic reticulum stress.
Heliyon
Sophonnithiprasert T,Aruksakunwong O,Tashiro E,Kondoh Y,Muroi M,Osada H,Imoto M,Watanapokasin R
Published figure using CHOP monoclonal antibody (Product # MA1-250) in Western Blot
Thu Oct 01 00:00:00 UTC 2020
Interaction between goniothalamin and peroxisomal multifunctional enzyme type 2 triggering endoplasmic reticulum stress.
Heliyon
Sophonnithiprasert T,Aruksakunwong O,Tashiro E,Kondoh Y,Muroi M,Osada H,Imoto M,Watanapokasin R
Published figure using CHOP monoclonal antibody (Product # MA1-250) in Western Blot
Thu Oct 01 00:00:00 UTC 2020
Ezetimibe Prevents Ischemia/Reperfusion-Induced Oxidative Stress and Up-Regulates Nrf2/ARE and UPR Signaling Pathways.
Antioxidants (Basel, Switzerland)
Peserico D,Stranieri C,Garbin U,Mozzini C C,Danese E,Cominacini L,Fratta Pasini AM
MA1-250 was used in Western Blotting to show that Ezetimibe affected UPR gene expression.
Thu Apr 23 00:00:00 UTC 2020
Ezetimibe Prevents Ischemia/Reperfusion-Induced Oxidative Stress and Up-Regulates Nrf2/ARE and UPR Signaling Pathways.
Antioxidants (Basel, Switzerland)
Peserico D,Stranieri C,Garbin U,Mozzini C C,Danese E,Cominacini L,Fratta Pasini AM
MA1-250 was used in Western Blotting to show that Ezetimibe affected UPR gene expression.
Thu Apr 23 00:00:00 UTC 2020
Activation of AMP-activated protein kinase attenuates ethanol-induced ER/oxidative stress and lipid phenotype in human pancreatic acinar cells.
Biochemical pharmacology
Srinivasan MP,Bhopale KK,Caracheo AA,Amer SM,Khan S,Kaphalia L,Loganathan G,Balamurugan AN,Kaphalia BS
MA1-250 was used in Western Blotting to suggest that EtOH-induced inactivation of AMPKα is closely related to ER/oxidative stress and synthesis of FAEEs, as activation of AMPKα by AICAR attenuates formation of FAEEs, ER/oxidative stress and lipogenesis, and improves inflammatory responses and mitochondrial bioenergetics.
Thu Oct 01 00:00:00 UTC 2020
Activation of AMP-activated protein kinase attenuates ethanol-induced ER/oxidative stress and lipid phenotype in human pancreatic acinar cells.
Biochemical pharmacology
Srinivasan MP,Bhopale KK,Caracheo AA,Amer SM,Khan S,Kaphalia L,Loganathan G,Balamurugan AN,Kaphalia BS
MA1-250 was used in Western Blotting to suggest that EtOH-induced inactivation of AMPKα is closely related to ER/oxidative stress and synthesis of FAEEs, as activation of AMPKα by AICAR attenuates formation of FAEEs, ER/oxidative stress and lipogenesis, and improves inflammatory responses and mitochondrial bioenergetics.
Thu Oct 01 00:00:00 UTC 2020
Systematic genetic mapping of necroptosis identifies SLC39A7 as modulator of death receptor trafficking.
Cell death and differentiation
Fauster A,Rebsamen M,Willmann KL,César-Razquin A,Girardi E,Bigenzahn JW,Schischlik F,Scorzoni S,Bruckner M,Konecka J,Hörmann K,Heinz LX,Boztug K,Superti-Furga G
MA1-250 was used in Western Blotting to investigate the genetic basis underlying necroptotic cell death.
Sat Jun 01 00:00:00 UTC 2019
The UPR-PERK pathway is not a promising therapeutic target for mutant SOD1-induced ALS.
Neurobiology of disease
Dzhashiashvili Y,Monckton CP,Shah HS,Kunjamma RB,Popko B
MA1-250 was used in Western Blotting to investigate the response to PERK haploinsufficiency, and the response to deficiency of its downstream effectors GADD34 and CHOP, in five distinct lines of mtSOD1 mice.
Mon Jul 01 00:00:00 UTC 2019
StarD5: an ER stress protein regulates plasma membrane and intracellular cholesterol homeostasis.
Journal of lipid research
Rodriguez-Agudo D,Malacrida L,Kakiyama G,Sparrer T,Fortes C,Maceyka M,Subler MA,Windle JJ,Gratton E,Pandak WM,Gil G
MA1-250 was used in Western Blotting to show that StarD5 is a stress-responsive protein that regulates PM cholesterol and intracellular cholesterol homeostasis.
Sat Jun 01 00:00:00 UTC 2019
StarD5: an ER stress protein regulates plasma membrane and intracellular cholesterol homeostasis.
Journal of lipid research
Rodriguez-Agudo D,Malacrida L,Kakiyama G,Sparrer T,Fortes C,Maceyka M,Subler MA,Windle JJ,Gratton E,Pandak WM,Gil G
MA1-250 was used in Western Blotting to show that StarD5 is a stress-responsive protein that regulates PM cholesterol and intracellular cholesterol homeostasis.
Sat Jun 01 00:00:00 UTC 2019
Increased ER Stress After Experimental Ischemic Optic Neuropathy and Improved RGC and Oligodendrocyte Survival After Treatment With Chemical Chaperon.
Investigative ophthalmology & visual science
Kumar V,Mesentier-Louro LA,Oh AJ,Heng K,Shariati MA,Huang H,Hu Y,Liao YJ
MA1-250 was used in Immunohistochemistry to study the expression of key molecules in the endoplasmic reticulum stress pathways following anterior ischemic optic neuropathy.
Wed May 01 00:00:00 UTC 2019
Rapamycin Rescues Endoplasmic Reticulum Stress-Induced Dry Eye Syndrome in Mice.
Investigative ophthalmology & visual science
Cho BJ,Hwang JS,Shin YJ,Kim JW,Chung TY,Hyon JY
MA1-250 was used in Western Blotting to investigate whether rapamycin protects tear production and the ocular surface during endoplasmic reticulum stress-induced dry eye syndrome in mice.
Fri Mar 01 00:00:00 UTC 2019
N-Linked Glycosylation-Dependent and -Independent Mechanisms Regulating CTRP12 Cleavage, Secretion, and Stability.
Biochemistry
Stewart AN,Tan SY,Clark DJ,Zhang H,Wong GW
MA1-250 was used in Western Blotting to highlight glycosylation-dependent and -independent mechanisms regulating CTRP12 cleavage, secretion, and protein stability.
Tue Feb 12 00:00:00 UTC 2019
Screening Mycobacterium tuberculosis Secreted Proteins Identifies Mpt64 as a Eukaryotic Membrane-Binding Bacterial Effector.
mSphere
Stamm CE,Pasko BL,Chaisavaneeyakorn S,Franco LH,Nair VR,Weigele BA,Alto NM,Shiloh MU
MA1-250 was used in Western Blotting to observe that Mpt64 impairs the ER-mediated unfolded protein response in macrophages.
Wed Jun 05 00:00:00 UTC 2019
The transporters SLC35A1 and SLC30A1 play opposite roles in cell survival upon VSV virus infection.
Scientific reports
Moskovskich A,Goldmann U,Kartnig F,Lindinger S,Konecka J,Fiume G,Girardi E,Superti-Furga G
MA1-250 was used in Western Blotting to characterise the role of host solute carriers in cell survival upon viral infection by performing unbiased genetic screens using a focused CRISPR knockout library.
Thu Jul 18 00:00:00 UTC 2019
Mast Cells Induce Blood Brain Barrier Damage in SCD by Causing Endoplasmic Reticulum Stress in the Endothelium.
Frontiers in cellular neuroscience
Tran H,Mittal A,Sagi V,Luk K,Nguyen A,Gupta M,Nguyen J,Lamarre Y,Lei J,Guedes A,Gupta K
MA1-250 was used in Western Blotting to examine the mechanism of mast cell-induced endothelial activation via endoplasmic reticulum stress mediated P-selectin expression in a transgenic mouse model of sickle cell disease.
Thu Oct 01 00:00:00 UTC 2020
The Integrated Stress Response Regulates Cell Health of Cardiac Progenitors.
Toxicological sciences : an official journal of the Society of Toxicology
Searfoss GH,Paisley BM,Goldstein KM,Baker TK,Willy JA
MA1-250 was used in Western Blotting to study stress induced apoptosis of cardiac progenitors in preventing damaged cells differentiating and undergoing self-renewal.
Tue Jan 01 00:00:00 UTC 2019
GRP78 translocation to the cell surface and O-GlcNAcylation of VE-Cadherin contribute to ER stress-mediated endothelial permeability.
Scientific reports
Lenin R,Nagy PG,Jha KA,Gangaraju R
MA1-250 was used in Western Blotting to test the hypothesis that increased ER stress via O-GlcNAcylation of VE-Cadherin likely contribute to endothelial permeability.
Thu Jul 25 00:00:00 UTC 2019
Target-Based Discovery of an Inhibitor of the Regulatory Phosphatase PPP1R15B.
Cell
Krzyzosiak A,Sigurdardottir A,Luh L,Carrara M,Das I,Schneider K,Bertolotti A
MA1-250 was used in Western Blotting to develop a method to enable target-based discovery of selective serine/threonine phosphatase inhibitors.
Thu Aug 23 00:00:00 UTC 2018
Target-Based Discovery of an Inhibitor of the Regulatory Phosphatase PPP1R15B.
Cell
Krzyzosiak A,Sigurdardottir A,Luh L,Carrara M,Das I,Schneider K,Bertolotti A
MA1-250 was used in Western Blotting to develop a method to enable target-based discovery of selective serine/threonine phosphatase inhibitors.
Thu Aug 23 00:00:00 UTC 2018
Deletion of Tmtc4 activates the unfolded protein response and causes postnatal hearing loss.
The Journal of clinical investigation
Li J,Akil O,Rouse SL,McLaughlin CW,Matthews IR,Lustig LR,Chan DK,Sherr EH
MA1-250 was used in Western Blotting to identify a novel mechanism for hearing impairment, highlighting a potential treatment approach for a broad range of human hearing loss disorders.
Thu Nov 01 00:00:00 UTC 2018
Gene Therapy with BMN 270 Results in Therapeutic Levels of FVIII in Mice and Primates and Normalization of Bleeding in Hemophilic Mice.
Molecular therapy : the journal of the American Society of Gene Therapy
Bunting S,Zhang L,Xie L,Bullens S,Mahimkar R,Fong S,Sandza K,Harmon D,Yates B,Handyside B,Sihn CR,Galicia N,Tsuruda L,O'Neill CA,Bagri A,Colosi P,Long S,Vehar G,Carter B
MA1-250 was used in Western Blotting to develop an adeno-associated virus 5 vector containing a B domain-deleted factor VIII gene with a liver-specific promoter, and study its use in haemophilic mice.
Wed Feb 07 00:00:00 UTC 2018
SNX14 mutations affect endoplasmic reticulum-associated neutral lipid metabolism in autosomal recessive spinocerebellar ataxia 20.
Human molecular genetics
Bryant D,Liu Y,Datta S,Hariri H,Seda M,Anderson G,Peskett E,Demetriou C,Sousa S,Jenkins D,Clayton P,Bitner-Glindzicz M,Moore GE,Henne WM,Stanier P
MA1-250 was used in Immunocytochemistry to determine the role of SNX14 in endoplasmic reticulum-lipid droplet crosstalk.
Fri Jun 01 00:00:00 UTC 2018
Featured Article: Deterioration of visual function mediated by senescence-associated endoplasmic reticulum stress in inflammatory tie2-TNF mice.
Experimental biology and medicine (Maywood, N.J.)
Lenin R,Nagy PG,Gentry J,Gangaraju R
MA1-250 was used in Western Blotting to investigate the relationship between endothelial dysfunction, endoplasmic reticulum (ER) stress, and cellular senescence in the development of retinal dysfunction.
Wed Aug 01 00:00:00 UTC 2018
Protective effect of curcumin against ultraviolet A irradiation‑induced photoaging in human dermal fibroblasts.
Molecular medicine reports
Liu X,Zhang R,Shi H,Li X,Li Y,Taha A,Xu C
Published figure using CHOP monoclonal antibody (Product # MA1-250) in Western Blot
Tue May 01 00:00:00 UTC 2018
Inhibition of euchromatin histone-lysine N-methyltransferase 2 sensitizes breast cancer cells to tumor necrosis factor-related apoptosis-inducing ligand through reactive oxygen species-mediated activating transcription factor 4-C/EBP homologous protein-death receptor 5 pathway activation.
Molecular carcinogenesis
Kim SY,Hong M,Heo SH,Park S,Kwon TK,Sung YH,Oh Y,Lee S,Yi GS,Kim I
MA1-250 was used in Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot to find that epigenetic regulation can contribute to the development of resistance to cancer therapeutics such as TRAIL, and further studies of unfolded protein responses and the associated epigenetic regulatory mechanisms may lead to the discovery of new molecular targets for effective cancer therapy.
Thu Nov 01 00:00:00 UTC 2018
Impaired Protein Quality Control During Left Ventricular Remodeling in Mice With Cardiac Restricted Overexpression of Tumor Necrosis Factor.
Circulation. Heart failure
Hartupee J,Szalai GD,Wang W,Ma X,Diwan A,Mann DL
MA1-250 was used in Western Blotting to study the relationship between chronic inflammation and protein quality control.
Fri Dec 01 00:00:00 UTC 2017
Discovery of a Benzamide Derivative That Protects Pancreatic β-Cells against Endoplasmic Reticulum Stress.
Journal of medicinal chemistry
Duan H,Li Y,Arora D,Xu D,Lim HY,Wang W
MA1-250 was used in Western Blotting to identify benzamide derivatives 13d as a novel class of β-cell protective agents against ER stress-induced dysfunction and that 13d significantly lowers blood glucose levels and increases β-cell population in a streptozotocin-induced diabetic mouse model.
Thu Jul 27 00:00:00 UTC 2017
Discovery of a Benzamide Derivative That Protects Pancreatic β-Cells against Endoplasmic Reticulum Stress.
Journal of medicinal chemistry
Duan H,Li Y,Arora D,Xu D,Lim HY,Wang W
MA1-250 was used in Western Blotting to identify benzamide derivatives 13d as a novel class of β-cell protective agents against ER stress-induced dysfunction and that 13d significantly lowers blood glucose levels and increases β-cell population in a streptozotocin-induced diabetic mouse model.
Thu Jul 27 00:00:00 UTC 2017
Succination of Protein Disulfide Isomerase Links Mitochondrial Stress and Endoplasmic Reticulum Stress in the Adipocyte During Diabetes.
Antioxidants & redox signaling
Manuel AM,Walla MD,Faccenda A,Martin SL,Tanis RM,Piroli GG,Adam J,Kantor B,Mutus B,Townsend DM,Frizzell N
MA1-250 was used in Western Blotting to investigate whether succination alters PDI oxidoreductase activity, directly linking mitochondrial stress and endoplasmic reticulum stress.
Fri Dec 01 00:00:00 UTC 2017
The integrated stress response in hypoxia-induced diffuse white matter injury.
The Journal of neuroscience : the official journal of the Society for Neuroscience
Clayton BL,Huang A,Kunjamma RB,Solanki A,Popko B
MA1-250 was used in Immunohistochemistry to examine the roles of the integrated stress response in preterm infant diffuse white matter injury, induced by hypoxia.
Tue Jul 18 00:00:00 UTC 2017
ER Stress Induced by Tunicamycin Triggers α-Synuclein Oligomerization, Dopaminergic Neurons Death and Locomotor Impairment: a New Model of Parkinson's Disease.
Molecular neurobiology
Cóppola-Segovia V,Cavarsan C,Maia FG,Ferraz AC,Nakao LS,Lima MM,Zanata SM
MA1250 was used in western blot to develop and characterize a new rat model of Parkinson's disease using the endoplasmic reticulum stressor tunicamycin
Sun Oct 01 00:00:00 UTC 2017
Effects of white light-emitting diode (LED) exposure on retinal pigment epithelium in vivo.
Journal of cellular and molecular medicine
Jaadane I,Villalpando Rodriguez GE,Boulenguez P,Chahory S,Carré S,Savoldelli M,Jonet L,Behar-Cohen F,Martinsons C,Torriglia A
Published figure using CHOP monoclonal antibody (Product # MA1-250) in Western Blot
Fri Dec 01 00:00:00 UTC 2017
EIF2S3 Mutations Associated with Severe X-Linked Intellectual Disability Syndrome MEHMO.
Human mutation
Skopkova M,Hennig F,Shin BS,Turner CE,Stanikova D,Brennerova K,Stanik J,Fischer U,Henden L,Müller U,Steinberger D,Leshinsky-Silver E,Bottani A,Kurdiova T,Ukropec J,Nyitrayova O,Kolnikova M,Klimes I,Borck G,Bahlo M,Haas SA,Kim JR,Lotspeich-Cole LE,Gasperikova D,Dever TE,Kalscheuer VM
Published figure using CHOP monoclonal antibody (Product # MA1-250) in Western Blot
Sat Apr 01 00:00:00 UTC 2017
EIF2S3 Mutations Associated with Severe X-Linked Intellectual Disability Syndrome MEHMO.
Human mutation
Skopkova M,Hennig F,Shin BS,Turner CE,Stanikova D,Brennerova K,Stanik J,Fischer U,Henden L,Müller U,Steinberger D,Leshinsky-Silver E,Bottani A,Kurdiova T,Ukropec J,Nyitrayova O,Kolnikova M,Klimes I,Borck G,Bahlo M,Haas SA,Kim JR,Lotspeich-Cole LE,Gasperikova D,Dever TE,Kalscheuer VM
Published figure using CHOP monoclonal antibody (Product # MA1-250) in Western Blot
Sat Apr 01 00:00:00 UTC 2017
Protective effects of Cervus nippon Temminck velvet antler polypeptides against MPP+‑induced cytotoxicity in SH‑SY5Y neuroblastoma cells.
Molecular medicine reports
Xin JL,Zhang Y,Li Y,Zhang LZ,Lin Y,Zheng LW
MA1-250 was used in Western Blotting to assist in understanding the mechanism underlying the protective effect of VAPs on neurons.
Sun Oct 01 00:00:00 UTC 2017
Casitas B-cell lymphoma (Cbl) proteins protect mammary epithelial cells from proteotoxicity of active c-Src accumulation.
Proceedings of the National Academy of Sciences of the United States of America
Mukhopadhyay C,Triplett A,Bargar T,Heckman C,Wagner KU,Naramura M
MA1250 was used in western blot to propose that casitas B-cell lymphoma family proteins protect mammary epithelial cells from proteotoxic stress-induced cell death by promoting turnover of active c-Src
Tue Dec 20 00:00:00 UTC 2016
Discovery, Synthesis, and Evaluation of 2,4-Diaminoquinazolines as a Novel Class of Pancreatic β-Cell-Protective Agents against Endoplasmic Reticulum (ER) Stress.
Journal of medicinal chemistry
Duan H,Lee JW,Moon SW,Arora D,Li Y,Lim HY,Wang W
MA1250 was used in western blot to discover and characterize beta-cell protective agents that prevent endoplasmic reticulum stress-induced dysfunction and death
Thu Sep 08 00:00:00 UTC 2016
miR-219 regulates neural progenitors by dampening apical Par protein-dependent Hedgehog signaling.
Development (Cambridge, England)
Hudish LI,Galati DF,Ravanelli AM,Pearson CG,Huang P,Appel B
MA1-250 was used in immunohistochemistry and western blot to assess regulation of neural progenitors by dampening apical Par protein-dependent Hedgehog signaling by miR-219
Fri Jul 01 00:00:00 UTC 2016
Rescue of Glaucomatous Neurodegeneration by Differentially Modulating Neuronal Endoplasmic Reticulum Stress Molecules.
The Journal of neuroscience : the official journal of the Society for Neuroscience
Yang L,Li S,Miao L,Huang H,Liang F,Teng X,Xu L,Wang Q,Xiao W,Ridder WH,Ferguson TA,Chen DF,Kaufman RJ,Hu Y
Published figure using CHOP monoclonal antibody (Product # MA1-250) in Western Blot
Wed May 25 00:00:00 UTC 2016
Rescue of Glaucomatous Neurodegeneration by Differentially Modulating Neuronal Endoplasmic Reticulum Stress Molecules.
The Journal of neuroscience : the official journal of the Society for Neuroscience
Yang L,Li S,Miao L,Huang H,Liang F,Teng X,Xu L,Wang Q,Xiao W,Ridder WH,Ferguson TA,Chen DF,Kaufman RJ,Hu Y
Published figure using CHOP monoclonal antibody (Product # MA1-250) in Western Blot
Wed May 25 00:00:00 UTC 2016
Rescue of Glaucomatous Neurodegeneration by Differentially Modulating Neuronal Endoplasmic Reticulum Stress Molecules.
The Journal of neuroscience : the official journal of the Society for Neuroscience
Yang L,Li S,Miao L,Huang H,Liang F,Teng X,Xu L,Wang Q,Xiao W,Ridder WH,Ferguson TA,Chen DF,Kaufman RJ,Hu Y
Published figure using CHOP monoclonal antibody (Product # MA1-250) in Western Blot
Wed May 25 00:00:00 UTC 2016
Amelioration of neuronal cell death in a spontaneous obese rat model by dietary restriction through modulation of ubiquitin proteasome system.
The Journal of nutritional biochemistry
Shruthi K,Reddy SS,Reddy PY,Shivalingam P,Harishankar N,Reddy GB
MA1-250 was used in western blot to characterize amelioration of neuronal cell death in a rat model of spontaneous obesity that is dietary-restricted through modulation of ubiquitin proteasome system
Fri Jul 01 00:00:00 UTC 2016
Neuronal Rap1 Regulates Energy Balance, Glucose Homeostasis, and Leptin Actions.
Cell reports
Kaneko K,Xu P,Cordonier EL,Chen SS,Ng A,Xu Y,Morozov A,Fukuda M
Published figure using CHOP monoclonal antibody (Product # MA1-250) in Western Blot
Tue Sep 13 00:00:00 UTC 2016
Regulation of PERK-eIF2α signalling by tuberous sclerosis complex-1 controls homoeostasis and survival of myelinating oligodendrocytes.
Nature communications
Jiang M,Liu L,He X,Wang H,Lin W,Wang H,Yoon SO,Wood TL,Lu QR
MA1-250 was used in immunohistochemistry and western blot to study the control of homoeostasis and survival of myelinating oligodendrocytes by regulation of PERK-eIF2alpha signaling by tuberous sclerosis complex-1
Fri Jul 15 00:00:00 UTC 2016
The Cataract-linked Mutant Connexin50D47A Causes Endoplasmic Reticulum Stress in Mouse Lenses.
The Journal of biological chemistry
Berthoud VM,Minogue PJ,Lambert PA,Snabb JI,Beyer EC
MA1-250 was used in Immunohistochemistry-immunofluorescence to assess whether expression of connexin50D47A leads to endoplasmic reticulum stress in the lens in vivo.
Fri Aug 19 00:00:00 UTC 2016
The Cataract-linked Mutant Connexin50D47A Causes Endoplasmic Reticulum Stress in Mouse Lenses.
The Journal of biological chemistry
Berthoud VM,Minogue PJ,Lambert PA,Snabb JI,Beyer EC
MA1-250 was used in Immunohistochemistry-immunofluorescence to assess whether expression of connexin50D47A leads to endoplasmic reticulum stress in the lens in vivo.
Fri Aug 19 00:00:00 UTC 2016
Preventing proteostasis diseases by selective inhibition of a phosphatase regulatory subunit.
Science (New York, N.Y.)
Das I,Krzyzosiak A,Schneider K,Wrabetz L,D'Antonio M,Barry N,Sigurdardottir A,Bertolotti A
MA1-250 was used in western blot to show that Sephin1, a selective inhibitor of protein phosphatase 1, protects mice from protein-misfolding disease.
Fri Apr 10 00:00:00 UTC 2015
Preventing proteostasis diseases by selective inhibition of a phosphatase regulatory subunit.
Science (New York, N.Y.)
Das I,Krzyzosiak A,Schneider K,Wrabetz L,D'Antonio M,Barry N,Sigurdardottir A,Bertolotti A
MA1-250 was used in western blot to show that Sephin1, a selective inhibitor of protein phosphatase 1, protects mice from protein-misfolding disease.
Fri Apr 10 00:00:00 UTC 2015
Basal autophagy maintains pancreatic acinar cell homeostasis and protein synthesis and prevents ER stress.
Proceedings of the National Academy of Sciences of the United States of America
Antonucci L,Fagman JB,Kim JY,Todoric J,Gukovsky I,Mackey M,Ellisman MH,Karin M
Published figure using CHOP monoclonal antibody (Product # MA1-250) in Western Blot
Tue Nov 10 00:00:00 UTC 2015
Identification of 5-nitrofuran-2-amide derivatives that induce apoptosis in triple negative breast cancer cells by activating C/EBP-homologous protein expression.
Bioorganic & medicinal chemistry
Duan H,Li Y,Lim HY,Wang W
MA1-250 was used in western blot to identify compounds that induce CHOP expression and investigate how they induce apoptosis in cancer cells.
Sat Aug 01 00:00:00 UTC 2015
Attenuation of oxygen fluctuation-induced endoplasmic reticulum stress in human lens epithelial cells.
Experimental and therapeutic medicine
Zheng XY,Xu J,Chen XI,Li W,Wang TY
MA1-250 was used in western blot to study oxygen-induced endoplasmic reticulum stress in the lens
Sun Nov 01 00:00:00 UTC 2015
Attenuation of oxygen fluctuation-induced endoplasmic reticulum stress in human lens epithelial cells.
Experimental and therapeutic medicine
Zheng XY,Xu J,Chen XI,Li W,Wang TY
MA1-250 was used in western blot to study oxygen-induced endoplasmic reticulum stress in the lens
Sun Nov 01 00:00:00 UTC 2015
Endothelial endoplasmic reticulum and nitrative stress in endothelial dysfunction in the atherogenic rabbit model.
Acta histochemica
Kruzliak P,Sabo J,Zulli A
MA1-250 was used in immunohistochemistry - paraffin section to test if endoplasmic reticulum stress and oxidative stress are both present in the endothelial layer of an aorta with atherosclerosis
Thu Oct 01 00:00:00 UTC 2015
Pharmaceutical integrated stress response enhancement protects oligodendrocytes and provides a potential multiple sclerosis therapeutic.
Nature communications
Way SW,Podojil JR,Clayton BL,Zaremba A,Collins TL,Kunjamma RB,Robinson AP,Brugarolas P,Miller RH,Miller SD,Popko B
Published figure using CHOP monoclonal antibody (Product # MA1-250) in Western Blot
Fri Mar 13 00:00:00 UTC 2015
Legionella suppresses the host unfolded protein response via multiple mechanisms.
Nature communications
Treacy-Abarca S,Mukherjee S
Published figure using CHOP monoclonal antibody (Product # MA1-250) in Western Blot
Wed Jul 29 00:00:00 UTC 2015
Legionella suppresses the host unfolded protein response via multiple mechanisms.
Nature communications
Treacy-Abarca S,Mukherjee S
Published figure using CHOP monoclonal antibody (Product # MA1-250) in Western Blot
Wed Jul 29 00:00:00 UTC 2015
CD36 deletion improves recovery from spinal cord injury.
Experimental neurology
Myers SA,Andres KR,Hagg T,Whittemore SR
Published figure using CHOP monoclonal antibody (Product # MA1-250) in Immunofluorescence
Sun Jun 01 00:00:00 UTC 2014
Impact of aging on heat shock protein expression in the substantia nigra and striatum of the female rat.
Cell and tissue research
Gleixner AM,Pulugulla SH,Pant DB,Posimo JM,Crum TS,Leak RK
MA1-250 was used in western blot to study age-dependent changes in the expression of a number of heat shock proteins in female rat substantia nigra and striatum
Tue Jul 01 00:00:00 UTC 2014
HKH40A downregulates GRP78/BiP expression in cancer cells.
Cell death & disease
Kosakowska-Cholody T,Lin J,Srideshikan SM,Scheffer L,Tarasova NI,Acharya JK
MA1-250 was used in western blot to investigate the effects of HKH40A in cancer cells
Thu May 22 00:00:00 UTC 2014
TUSC3 loss alters the ER stress response and accelerates prostate cancer growth in vivo.
Scientific reports
Horak P,Tomasich E,Vaňhara P,Kratochvílová K,Anees M,Marhold M,Lemberger CE,Gerschpacher M,Horvat R,Sibilia M,Pils D,Krainer M
Published figure using CHOP monoclonal antibody (Product # MA1-250) in Western Blot
Fri Jan 17 00:00:00 UTC 2014
The accumulation of misfolded proteins in the mitochondrial matrix is sensed by PINK1 to induce PARK2/Parkin-mediated mitophagy of polarized mitochondria.
Autophagy
Jin SM,Youle RJ
MA1-250 was used in Western Blotting to suggest that the accumulation of unfolded proteins in mitochondria is a physiological trigger of mitophagy.
Fri Nov 01 00:00:00 UTC 2013
Oxidized lipids activate autophagy in a JNK-dependent manner by stimulating the endoplasmic reticulum stress response.
Redox biology
Haberzettl P,Hill BG
MA1-250 was used in immunocytochemistry to study the roles of JNK and the ER stress response in the activation of autophagy by oxidized lipids
Wed May 13 00:00:00 UTC 2015
The transcription factor c-Jun protects against sustained hepatic endoplasmic reticulum stress thereby promoting hepatocyte survival.
Hepatology (Baltimore, Md.)
Fuest M,Willim K,MacNelly S,Fellner N,Resch GP,Blum HE,Hasselblatt P
MA1-250 was used in western blot to investigate the protective effect of c-Jun against hepatic endoplasmic reticulum stress
Wed Feb 01 00:00:00 UTC 2012
Laforin is required for the functional activation of malin in endoplasmic reticulum stress resistance in neuronal cells.
The FEBS journal
Zeng L,Wang Y,Baba O,Zheng P,Liu Y,Liu Y
Published figure using CHOP monoclonal antibody (Product # MA1-250) in Western Blot
Sun Jul 01 00:00:00 UTC 2012
Xanthohumol impairs autophagosome maturation through direct inhibition of valosin-containing protein.
ACS chemical biology
Sasazawa Y,Kanagaki S,Tashiro E,Nogawa T,Muroi M,Kondoh Y,Osada H,Imoto M
MA1-250 was used in western blot to study the role of valosin-containing protein in the mechanism by which xanthohumol inhibits the maturation of autophagosomes
Fri May 18 00:00:00 UTC 2012
Protein aggregation of SERCA2 mutants associated with Darier disease elicits ER stress and apoptosis in keratinocytes.
Journal of cell science
Wang Y,Bruce AT,Tu C,Ma K,Zeng L,Zheng P,Liu Y,Liu Y
MA1-250 was used in western blot to study the effect of aggregation of SERCA2 mutants associated with Darier disease on ER stress and keratinocyte apoptosis
Tue Nov 01 00:00:00 UTC 2011
Regulated increase in folding capacity prevents unfolded protein stress in the ER.
Journal of cell science
Christis C,Fullaondo A,Schildknegt D,Mkrtchian S,Heck AJ,Braakman I
MA1-250 was used in western blot to investigate the change of the folding capacity of ER due to thyroid stimulating hormone activation in thyrocytes
Mon Mar 01 00:00:00 UTC 2010
Screening of cell death genes with a mammalian genome-wide RNAi library.
Journal of biochemistry
Tsujii H,Eguchi Y,Chenchik A,Mizutani T,Yamada K,Tsujimoto Y
MA1-250 was used in western blot to identify genes related to cell death by using a mammalian genome-wide RNAi library
Sun Aug 01 00:00:00 UTC 2010
DHA alters expression of target proteins of cancer therapy in chemotherapy resistant SW620 colon cancer cells.
Nutrition and cancer
Slagsvold JE,Pettersen CH,Størvold GL,Follestad T,Krokan HE,Schønberg SA
MA1-250 was used in western blot to investigate the effect of DHA on specific colon cancer treatment by chemicals
Mon Oct 04 00:00:00 UTC 2010
Cadmium induces Wnt signaling to upregulate proliferation and survival genes in sub-confluent kidney proximal tubule cells.
Molecular cancer
Chakraborty PK,Lee WK,Molitor M,Wolff NA,Thévenod F
Published figure using CHOP monoclonal antibody (Product # MA1-250) in Western Blot
Sat May 08 00:00:00 UTC 2010
Methods for monitoring endoplasmic reticulum stress and the unfolded protein response.
International journal of cell biology
Samali A,Fitzgerald U,Deegan S,Gupta S
MA1-250 was used in western blot to evaluate different methods for the detection of endoplasmic reticulum stress and the unfolded protein response
Thu Jul 14 00:00:00 UTC 2011
High dietary taurine reduces apoptosis and atherosclerosis in the left main coronary artery: association with reduced CCAAT/enhancer binding protein homologous protein and total plasma homocysteine but not lipidemia.
Hypertension (Dallas, Tex. : 1979)
Zulli A,Lau E,Wijaya BP,Jin X,Sutarga K,Schwartz GD,Learmont J,Wookey PJ,Zinellu A,Carru C,Hare DL
MA1-250 was used in Immunohistochemistry to determine whether taurine could specifically protect against coronary artery disease during an atherogenic diet and whether taurine affects the lipid profile, metabolites of methionine, and endothelial atherogenic systems.
Mon Jun 01 00:00:00 UTC 2009
Role of endoplasmic reticulum stress in acrolein-induced endothelial activation.
Toxicology and applied pharmacology
Haberzettl P,Vladykovskaya E,Srivastava S,Bhatnagar A
MA1-250 was used in Western Blot to suggest that exposure to acrolein induces ER stress and triggers the unfolded protein response and that NF-kappaB activation and stimulation of cytokine production by acrolein could be attributed, in part, to ER stress.
Thu Jan 01 00:00:00 UTC 2009
Effects of ubiquilin 1 on the unfolded protein response.
Journal of molecular neuroscience : MN
Lu A,Hiltunen M,Romano DM,Soininen H,Hyman BT,Bertram L,Tanzi RE
MA1-250 was used in western blot to investigate the influence of ubiquilin 1 on the unfolded protein response and its role in Alzheimer disease
Fri May 01 00:00:00 UTC 2009
An upstream open reading frame regulates translation of GADD34 during cellular stresses that induce eIF2alpha phosphorylation.
The Journal of biological chemistry
Lee YY,Cevallos RC,Jan E
MA1-250 was used in western blot to study the role of an upstream ORF in the transcritional regulation of GADD34 under conditions that induce phosphorylation of eIF2alpha
Fri Mar 13 00:00:00 UTC 2009
Comparative proteomics profiling of a phospholamban mutant mouse model of dilated cardiomyopathy reveals progressive intracellular stress responses.
Molecular & cellular proteomics : MCP
Gramolini AO,Kislinger T,Alikhani-Koopaei R,Fong V,Thompson NJ,Isserlin R,Sharma P,Oudit GY,Trivieri MG,Fagan A,Kannan A,Higgins DG,Huedig H,Hess G,Arab S,Seidman JG,Seidman CE,Frey B,Perry M,Backx PH,Liu PP,MacLennan DH,Emili A
MA1-250 was used in western blot to perform the global proteomics surveys of cardiac ventricle of a phospholamban mutant mouse
Sat Mar 01 00:00:00 UTC 2008
CHOP-Dependent stress-inducible expression of a novel form of carbonic anhydrase VI.
Molecular and cellular biology
Sok J,Wang XZ,Batchvarova N,Kuroda M,Harding H,Ron D
MA1-250 was used in western blot to investigate the role of carbonic anhydrase VI during CHOP-dependent expression.
Fri Jan 01 00:00:00 UTC 1999
Cloning of mammalian Ire1 reveals diversity in the ER stress responses.
The EMBO journal
Wang XZ,Harding HP,Zhang Y,Jolicoeur EM,Kuroda M,Ron D
MA1-250 was used in immunocytochemistry to demonstrate that Ire1 plays a role in multiple facets of the ER stress-response
Thu Oct 01 00:00:00 UTC 1998
Inhibition of adipogenesis by the stress-induced protein CHOP (Gadd153).
The EMBO journal
Batchvarova N,Wang XZ,Ron D
MA1-250 was used in western blot to investigate how the stress-induced protein CHOP affects adipogenesis
Mon Oct 02 00:00:00 UTC 1995
