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COL5A2 is an alpha chain for one of the low abundance fibrillar collagens. Fibrillar collagen molecules are trimers that can be composed of one or more types of alpha chains. Type V collagen is found in tissues containing type I collagen and appears to regulate the assembly of heterotypic fibers composed of both type I and type V collagen. This protein is closely related to type XI collagen and it is possible that the collagen chains of types V and XI constitute a single collagen type with tissue-specific chain combinations.
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Protein Aliases: AB collagen; Collagen alpha-2(V) chain; collagen, fetal membrane, A polypeptide; collagen, type V, alpha 2; type V preprocollagen alpha 2 chain
Gene Aliases: COL5A2; EDSC
UniProt ID: (Human) P05997
Entrez Gene ID: (Human) 1290
Molecular Function: extracellular matrix structural protein