This Antibody was verified by Cell Treatment to ensure that the antibody binds to the antigen stated. View Details
Intact IgG appears on a non-reducing gel as ~150 kDa band and upon reduction generating a ~25 kDa light chain band and a ~50 kDa heavy chain.
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire.
MIG belongs to a family of chemoattractant cytokines that play a role in monocyte, and T lymphocyte chemoattraction. MIG is expressed in monocytes/macrophages, hepatocytes, fibroblasts, keratinocytes, and endothelial cells in response to interferon-gamma. MIG is related functionally to interferon-inducible protein 10 (IP10), as both bind to the CXCR3 receptor to inhibit endothelial cell chemotaxis, and growth factor-induced angiogenesis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: C-X-C motif chemokine 9; chemokine (C-X-C motif) ligand 9; CMK; crg-10; gamma interferon-induced monokine; Gamma-interferon-induced monokine; HuMIG; M119; MIG; monokine induced by gamma interferon; Monokine induced by interferon-gamma; Protein m119; SCYB9; small inducible cytokine B subfamily (Cys-X-Cys), member 9; Small-inducible cytokine B9
Gene Aliases: BB139920; CMK; crg-10; CXCL9; Humig; MIG; MuMIG; SCYB9