The cathepsin family of proteolytic enzymes contains several diverse classes of proteases. The cysteine protease class comprises cathepsins B, L, H, K, S, and O. The aspartyl protease class is composed of cathepsins D and E. Cathepsin G is in the serine protease class. Most cathepsins are lysosomal and each is involved in various cellular events such as peptide biosynthesis and protein degradation. The propeptide region of cathepsin H is highly homologous to other cathepsins. This region is thought to play a role in the processing of cysteine proteases. Cathepsin H is thought to be involved in several pathological conditions, including neuro degenerative disorders and cancer.
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Protein Aliases: aleurain; CATH; cathepsin B3; cathepsin BA; Cathepsin H; Cathepsin H heavy chain; Cathepsin H light chain; Cathepsin H mini chain; N-benzoylarginine-beta-naphthylamide hydrolase; Pro-cathepsin H
Gene Aliases: ACC-4; ACC-5; ACC4; ACC5; CPSB; CTSH
UniProt ID: (Human) P09668
Entrez Gene ID: (Human) 1512
Molecular Function: cysteine protease