The protein encoded by this gene is a member of the keratin family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. The type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains. This cytokeratin is a major cellular protein of mature enterocytes and goblet cells and is specifically expressed in the gastric and intestinal mucosa. The type I cytokeratin genes are clustered in a region of chromosome 17q12-q21.
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Protein Aliases: CK 20; CK-20; CK-21; CK20; Cytokeratin 20; cytokeratin 21; Cytokeratin-20; Cytokeratin-21; K20; keratin 20; keratin 20, type I; Keratin, type I cytoskeletal 20; Keratin-20; KRT20; KRT21; Protein IT
Gene Aliases: 9030623C06Rik; CD20; CK-20; CK20; K20; KRT20; KRT21