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Invitrogen
DIXDC1 Monoclonal Antibody (OTI6B6)
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Product Details
MA5-26153
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Non-human primate
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
OTI6B6
Immunogen
Full length human recombinant protein of DIXDC1 produced in HEK293T cell
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 1% BSA, 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2724214
Target Information
This gene encodes one of four subunits of the splicing factor 3B. The protein encoded by this gene cross-links to a region in the pre-mRNA immediately upstream of the branchpoint sequence in pre-mRNA in the prespliceosomal complex A. It also may be involved in the assembly of the B, C and E spliceosomal complexes. In addition to RNA-binding activity, this protein interacts directly and highly specifically with subunit 2 of the splicing factor 3B. This protein contains two N-terminal RNA-recognition motifs (RRMs), consistent with the observation that it binds directly to pre-mRNA.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Coiled-coil protein DIX1; Coiled-coil-DIX1; DIX domain-containing protein 1; Dixin
Gene Aliases: CCD1; DIXDC1; KIAA1735
UniProt ID: (Human) Q155Q3
Entrez Gene ID: (Human) 85458
cell cycle
cerebral cortex radially oriented cell migration
forebrain ventricular zone progenitor cell division
regulation of actin cytoskeleton organization
negative regulation of neuron differentiation
canonical Wnt signaling pathway
regulation of microtubule cytoskeleton organization
positive regulation of canonical Wnt signaling pathway
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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