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|Tested species reactivity||Human|
|Host / Isotype||Mouse / IgG1|
|Immunogen||Purified recombinant fragment of human DKK3 (amino acids: 91-350 ) expressed in E. Coli.|
|Storage buffer||PBS with 0.5% proprietary stabilizer|
|Contains||0.05% sodium azide|
|Storage Conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
|Tested Applications||Dilution *|
|Flow Cytometry (Flow)||1:200 - 1:400|
|Immunohistochemistry (IHC)||1:200 - 1:1000|
|Western Blot (WB)||1:500 - 1:2000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
MA5-17067 targets DKK3 in FACS, IHC, pep-ELISA, and WB applications and shows reactivity with Human samples.
The MA5-17067 immunogen is purified recombinant fragment of human DKK3 (amino acids: 91-350 ) expressed in E. Coli.
MA5-17067 detects DKK3 which has a predicted molecular weight of approximately 38.3kDa.
This gene encodes a protein that is a member of the dickkopf family. The secreted protein contains two cysteine rich regions and is involved in embryonic development through its interactions with the Wnt signaling pathway. The expression of this gene is decreased in a variety of cancer cell lines and it may function as a tumor suppressor gene. Alternative splicing results in multiple transcript variants encoding the same protein.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
dickkopf 3 homolog; dickkopf homolog 3; Dickkopf-3; Dickkopf-related protein 3; dkk-3; hDkk-3; regulated in glioma; RIG-like 5-6; RIG-like 7-1
DKK3; REIC; RIG; UNQ258/PRO295