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|Tested species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Recombinant fragment corresponding to a region within amino acids 633 and 919 of Human DNA Ligase I|
|Purification||Antigen affinity chromatography|
|Storage buffer||0.1M tris glycine, pH 7, with 10% glycerol|
|Storage Conditions||-20° C, Avoid Freeze/Thaw Cycles|
|Tested Applications||Dilution *|
|Western Blot (WB)||1:500-1:3000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
PA5-27820 targets DNA Ligase I in WB applications and shows reactivity with Human samples.
The PA5-27820 immunogen is recombinant fragment corresponding to a region within amino acids 633 and 919 of Human DNA Ligase I.
LIG1 encodes DNA ligase I, with functions in DNA replication and the base excision repair process. Mutations in LIG1 that lead to DNA ligase I deficiency result in immunodeficiency and increased sensitivity to DNA-damaging agents.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
ligase I, DNA, ATP-dependent; polydeoxyribonucleotide synthase [ATP] 1