Product References
p21 promotes error-free replication-coupled DNA double-strand break repair.
Nucleic acids research
Mauro M,Rego MA,Boisvert RA,Esashi F,Cavallo F,Jasin M,Howlett NG
MA5-13235 was used in western blot to study the role of p21 in error-free replication-coupled DNA double-strand break repair.
Sat Sep 01 00:00:00 EDT 2012
Gefitinib radiosensitizes stem-like glioma cells: inhibition of epidermal growth factor receptor-Akt-DNA-PK signaling, accompanied by inhibition of DNA double-strand break repair.
International journal of radiation oncology, biology, physics
Kang KB,Zhu C,Wong YL,Gao Q,Ty A,Wong MC
MA5-13235 was used in western blot to study the molecular mechanism by which gefitinib radiosensitizes brain tumor stem cells
Tue May 01 00:00:00 EDT 2012
Ku counteracts mobilization of PARP1 and MRN in chromatin damaged with DNA double-strand breaks.
Nucleic acids research
Cheng Q,Barboule N,Frit P,Gomez D,Bombarde O,Couderc B,Ren GS,Salles B,Calsou P
MA5-13235 was used in western blot to study the role of PARP1 and MRN proteins in the repair of DNA double strand breaks
Thu Dec 01 00:00:00 EST 2011
The Ku-dependent non-homologous end-joining pathway contributes to low-dose radiation-stimulated cell survival.
Journal of cellular physiology
Yu X,Wang H,Wang P,Chen BP,Wang Y
MA5-13235 was used in western blot to study low-dose radiation induction of cell survival and the mechanistic role of Ku-dependent non-homologous end joining
Tue Feb 01 00:00:00 EST 2011
A DNA-dependent stress response involving DNA-PK occurs in hypoxic cells and contributes to cellular adaptation to hypoxia.
Journal of cell science
Bouquet F,Ousset M,Biard D,Fallone F,Dauvillier S,Frit P,Salles B,Muller C
MA5-13235 was used in immunocytochemistry and western blot to study a DNA-dependent stress response involving DNA-PK in hypoxic cells that contributes to cellular adaptation to hypoxia
Wed Jun 01 00:00:00 EDT 2011
Tel2 structure and function in the Hsp90-dependent maturation of mTOR and ATR complexes.
Genes & development
Takai H,Xie Y,de Lange T,Pavletich NP
MA5-13235 was used in western blot to study the role of Tel2 in the Hsp90-dependent maturation of mTOR and ATR complexes
Wed Sep 15 00:00:00 EDT 2010
Identification of Filamin A as a BRCA1-interacting protein required for efficient DNA repair.
Cell cycle (Georgetown, Tex.)
Velkova A,Carvalho MA,Johnson JO,Tavtigian SV,Monteiro AN
MA5-13235 was used in western blot to study the interaction between the BRCA protein and filamin A and its role in efficient DNA repair
Thu Apr 01 00:00:00 EDT 2010
Defective Artemis causes mild telomere dysfunction.
Genome integrity
Yasaei H,Slijepcevic P
MA5-13235 was used in western blot to study the role of defective Artemis in telomere dysfunction
Wed May 26 00:00:00 EDT 2010
The effect of DNA-dependent protein kinase on adeno-associated virus replication.
PloS one
Choi YK,Nash K,Byrne BJ,Muzyczka N,Song S
MA5-13235 was used in blocking or activating experiment to study the role of DNA-dependent protein kinase in adeno-associated virus replication
Mon Dec 20 00:00:00 EST 2010
ARTEMIS nuclease facilitates apoptotic chromatin cleavage.
Cancer research
Britton S,Frit P,Biard D,Salles B,Calsou P
MA5-13235 was used in western blot to study the role of ARTEMIS nuclease in apoptotic chromatin cleavage
Thu Oct 15 00:00:00 EDT 2009
Adeno-associated virus site-specific integration is mediated by proteins of the nonhomologous end-joining pathway.
Journal of virology
Daya S,Cortez N,Berns KI
MA5-13235 was used in immunoprecipitation to study the mechanism of adeno-associated virus site-specific integration
Sun Nov 01 00:00:00 EDT 2009
DNA-dependent protein kinase is a novel interaction partner for Ets-1 isoforms.
Biochemical and biophysical research communications
Choul-li S,Drobecq H,Aumercier M
MA5-13235 was used in western blot to study the interaction of DNA-PK with the Ets-1 transcription factor
Fri Dec 18 00:00:00 EST 2009
Association of autoantibodies with Ku and DNA repair proteins in connective tissue diseases.
Rheumatology (Oxford, England)
Schild-Poulter C,Su A,Shih A,Kelly OP,Fritzler MJ,Goldstein R,Haché RJ
MA5-13235 was used in ChIP assay to study autoantibodies to Ku and DNA repair proteins in connective tissue diseases
Fri Feb 01 00:00:00 EST 2008
Analytical biochemistry of DNA--protein assemblies from crude cell extracts.
Nucleic acids research
Hégarat N,Cardoso GM,Rusconi F,Francois JC,Praseuth D
MA5-13235 was used in western blot to develop an efficient method for the purification of DNA-protein complexes from crude extracts
Wed Aug 15 00:00:00 EDT 2007
The catalytic subunit of DNA-protein kinase (DNA-PKcs) is not required for Ig class-switch recombination.
Proceedings of the National Academy of Sciences of the United States of America
Kiefer K,Oshinsky J,Kim J,Nakajima PB,Bosma GC,Bosma MJ
MA5-13235 was used in western blot to study the mechanism for Ig class-switch recombination
Tue Feb 20 00:00:00 EST 2007
Interplay between Cernunnos-XLF and nonhomologous end-joining proteins at DNA ends in the cell.
The Journal of biological chemistry
Wu PY,Frit P,Malivert L,Revy P,Biard D,Salles B,Calsou P
MA5-13235 was used in western blot to study the roles of Cernunnos-XLF and nonhomologous end-joining proteins at DNA ends
Fri Nov 02 00:00:00 EDT 2007
DNA end joining activity is reduced in Alzheimer's disease.
Neurobiology of aging
Shackelford DA
MA5-13235 was used in western blot to study the role of DNA-dependent protein kinase in reduced DNA end joining activity in Alzheimer's disease
Sat Apr 01 00:00:00 EST 2006
The metallo-beta-lactamase/beta-CASP domain of Artemis constitutes the catalytic core for V(D)J recombination.
The Journal of experimental medicine
Poinsignon C,Moshous D,Callebaut I,de Chasseval R,Villey I,de Villartay JP
MA5-13235 was used in western blot to study the role of the metallo-beta-lactamase/beta-CASP domain of Artemis as the catalytic core for V(D)J recombination
Mon Feb 02 00:00:00 EST 2004
DNA-dependent PK inhibits adeno-associated virus DNA integration.
Proceedings of the National Academy of Sciences of the United States of America
Song S,Lu Y,Choi YK,Han Y,Tang Q,Zhao G,Berns KI,Flotte TR
MA5-13235 was used in western blot to study the inhibitory effect of DNA-PK on adeno-associated virus integration in mouse liver in vitro and in vivo
Tue Feb 17 00:00:00 EST 2004
Reduced DNA-dependent protein kinase activity in two cell lines derived from adult cancer patients with late radionecrosis.
Oncogene
Loong SL,Korzh S,Price A
MA5-13235 was used in western blot to study the reduced DNA-PK activity of two immortalized lymphoblastoid cell lines from adult cancer patients suffering late radionecrosis and the significance for radionecrosis susceptibility
Thu Jul 15 00:00:00 EDT 2004
Mutational analysis of terminal deoxynucleotidyltransferase-mediated N-nucleotide addition in V(D)J recombination.
Journal of immunology (Baltimore, Md. : 1950)
Repasky JA,Corbett E,Boboila C,Schatz DG
MA5-13235 was used in immunoprecipitation to study the role of terminal deoxynucleotidyltransferase in V(D)J recombination
Sat May 01 00:00:00 EDT 2004
Backup pathways of NHEJ are suppressed by DNA-PK.
Journal of cellular biochemistry
Perrault R,Wang H,Wang M,Rosidi B,Iliakis G
MA5-13235 was used in western blot to study the suppression of alternative, backup pathways of non-homolgous end joining by DNA-PK
Thu Jul 01 00:00:00 EDT 2004
Ku70/Ku80 and DNA-dependent protein kinase catalytic subunit modulate RAG-mediated cleavage: implications for the enforcement of the 12/23 rule.
The Journal of biological chemistry
Sawchuk DJ,Mansilla-Soto J,Alarcon C,Singha NC,Langen H,Bianchi ME,Lees-Miller SP,Nussenzweig MC,Cortes P
MA5-13235 was used in western blot to study the role of Ku70/80 and DNA-PK in regulating RAG-mediated cleavage and the significance for the 12/23 rule specificity
Fri Jul 09 00:00:00 EDT 2004
Possible anti-recombinogenic role of Bloom's syndrome helicase in double-strand break processing.
Nucleic acids research
Onclercq-Delic R,Calsou P,Delteil C,Salles B,Papadopoulo D,Amor-Guéret M
MA5-13235 was used in western blot to study the potential anti-recombinogenic role of BLM DNA helicase in double-strand break processing
Sat Nov 01 00:00:00 EST 2003
Biochemical evidence for Ku-independent backup pathways of NHEJ.
Nucleic acids research
Wang H,Perrault AR,Takeda Y,Qin W,Wang H,Iliakis G
MA5-13235 was used in western blot to study alternative backup pathways of non-homologous end joining that are independent of Ku
Mon Sep 15 00:00:00 EDT 2003
Regulation of neuregulin/ErbB signaling by contractile activity in skeletal muscle.
American journal of physiology. Cell physiology
Lebrasseur NK,Coté GM,Miller TA,Fielding RA,Sawyer DB
MA5-13235 was used in western blot to study the regulation of neuregulin/ErbB signaling by contractile activity in skeletal muscle
Thu May 01 00:00:00 EDT 2003
Expression of Ku86 confers favorable outcome of tonsillar carcinoma treated with radiotherapy.
Head & neck
Friesland S,Kanter-Lewensohn L,Tell R,Munck-Wikland E,Lewensohn R,Nilsson A
MA5-13235 was used in immunohistochemistry to study the correlation between Ku86 expression and favorable outcome in tonsillar carcinoma treated with radiotherapy
Tue Apr 01 00:00:00 EST 2003
Distinct pathways of nonhomologous end joining that are differentially regulated by DNA-dependent protein kinase-mediated phosphorylation.
The Journal of biological chemistry
Udayakumar D,Bladen CL,Hudson FZ,Dynan WS
MA5-13235 was used in western blot to study two biochemically distinct pathways of non-homologous end joining that are differentially regulated by DNA-PK
Fri Oct 24 00:00:00 EDT 2003
Hairpin opening and overhang processing by an Artemis/DNA-dependent protein kinase complex in nonhomologous end joining and V(D)J recombination.
Cell
Ma Y,Pannicke U,Schwarz K,Lieber MR
MA5-13235 was used in immunoprecipitation and western blot to study the function of an Artemis/DNA-dependent protein kinase complex in nonhomologous end joining and V(D)J recombination
Fri Mar 22 00:00:00 EST 2002
The p53 response to DNA damage in vivo is independent of DNA-dependent protein kinase.
Molecular and cellular biology
Jhappan C,Yusufzai TM,Anderson S,Anver MR,Merlino G
MA5-13235 was used in western blot to study whether DNA-dependent protein kinase is involved in the p53-mediated response to DNA damage
Thu Jun 01 00:00:00 EDT 2000
Interactions of the DNA ligase IV-XRCC4 complex with DNA ends and the DNA-dependent protein kinase.
The Journal of biological chemistry
Chen L,Trujillo K,Sung P,Tomkinson AE
MA5-13235 was used in western blot to study the interactions of the DNA ligase IV-XRCC4 complex with DNA ends and the DNA-dependent protein kinase
Fri Aug 25 00:00:00 EDT 2000
Ku antigen-DNA conformation determines the activation of DNA-dependent protein kinase and DNA sequence-directed repression of mouse mammary tumor virus transcription.
Molecular and cellular biology
Giffin W,Gong W,Schild-Poulter C,Haché RJ
MA5-13235 was used in EMSA to study the mechanism by which Ku antigen-DNA conformation modulates the repression of MMTV transcription
Tue Jun 01 00:00:00 EDT 1999
A targeted DNA-PKcs-null mutation reveals DNA-PK-independent functions for KU in V(D)J recombination.
Immunity
Gao Y,Chaudhuri J,Zhu C,Davidson L,Weaver DT,Alt FW
MA5-13235 was used in western blot to study the DNA-PK-independent functions of Ku70 and Ku80 in V(D)J recombination
Tue Sep 01 00:00:00 EDT 1998
