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Proteintech
DOCK7 Polyclonal Antibody
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Product Details
13000-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
DOCK7 Fusion Protein Ag3671 (447-798 aa encoded by BC016392)
Conjugate
Form
Liquid
Concentration
0.13 mg/mL
Amount
19.5 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Multiple isoforms of DOCK 7 exist due to alternative splicing events. The DOCK 7 antibody (13000-1-AP) can recognize all isoforms.
Immunogen sequence: MAGMYEAVN EVYKVLIPIH EANRDAKKLS TIHGKLQEAF SKIVHQDGKR MFGTYFRVGF YGTKFGDLDE QEFVYKEPAI TKLAEISHRL EGFYGERFGE DVVEVIKDSN PVDKCKLDPN KAYIQITYVE PYFDTYEMKD RITYFDKNYN LRRFMYCTPF TLDGRAHGEL HEQFKRKTIL TTSHAFPYIK TRVNVTHKEE IILTPIEVAI EDMQKKTQEL AFATHQDPAD PKMLQMVLQG SVGTTVNQGP LEVAQVFLSE IPSDPKLFRH HNKLRLCFKD FTKRCEDALR KNKSLIGPDQ KEYQRELERN YHRLKEALQP LINRKIPQLY KAVLPVTCHR DSFSRMSLRK MDL (447-798 aa encoded by BC016392)
Target Information
The protein encoded by this gene is a guanine nucleotide exchange factor (GEF) that plays a role in axon formation and neuronal polarization. The encoded protein displays GEF activity toward RAC1 and RAC3 Rho small GTPases but not toward CDC42. Several transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Dedicator of cytokinesis protein 7; guanine nucleotide exchange factor for Rac GTPases; guanine-nucleotde exchange factor; guanine-nucleotide exchange factor; protein moonlight; unnamed protein product
Gene Aliases: 3110056M06Rik; DEE23; DOCK7; EIEE23; Gm430; KIAA1771; m; ZIR2
UniProt ID: (Human) Q96N67
Entrez Gene ID: (Human) 85440, (Mouse) 67299, (Rat) 313388
microtubule cytoskeleton organization
small GTPase mediated signal transduction
nervous system development
axonogenesis
Rac protein signal transduction
interkinetic nuclear migration
cell differentiation
neuron projection development
regulation of Rho protein signal transduction
establishment of neuroblast polarity
regulation of neurogenesis
negative regulation of cold-induced thermogenesis
positive regulation of vascular associated smooth muscle cell migration
hematopoietic progenitor cell differentiation
multicellular organism development
positive regulation of peptidyl-serine phosphorylation
pigmentation
activation of GTPase activity
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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