Proteintech

DOCK7 Polyclonal Antibody

FIGURE: 1 / 8

DOCK7 Antibody (13000-1-AP) in WB

Mouse brain tissue were subjected to SDS PAGE followed by western blot with 13000-1-AP (DOCK7 antibody) at dilution of 1:300 incubated at room temperature for 1.5 hours.

DOCK7 Antibody in Immunoprecipitation (IP)

Product Image Gallery

Product Details

13000-1-AP

Applications

Tested Dilution

Publications

Western Blot (WB)

1:1,000-1:6,000

View 2 publications 2 publications

Immunoprecipitation (IP)

0.5-4.0 µg

Product Specifications

Species Reactivity

Human, Mouse, Rat

Published species

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

DOCK7 Fusion Protein Ag3671 (447-798 aa encoded by BC016392)

View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.13 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

Multiple isoforms of DOCK 7 exist due to alternative splicing events. The DOCK 7 antibody (13000-1-AP) can recognize all isoforms.

Immunogen sequence: MAGMYEAVN EVYKVLIPIH EANRDAKKLS TIHGKLQEAF SKIVHQDGKR MFGTYFRVGF YGTKFGDLDE QEFVYKEPAI TKLAEISHRL EGFYGERFGE DVVEVIKDSN PVDKCKLDPN KAYIQITYVE PYFDTYEMKD RITYFDKNYN LRRFMYCTPF TLDGRAHGEL HEQFKRKTIL TTSHAFPYIK TRVNVTHKEE IILTPIEVAI EDMQKKTQEL AFATHQDPAD PKMLQMVLQG SVGTTVNQGP LEVAQVFLSE IPSDPKLFRH HNKLRLCFKD FTKRCEDALR KNKSLIGPDQ KEYQRELERN YHRLKEALQP LINRKIPQLY KAVLPVTCHR DSFSRMSLRK MDL (447-798 aa encoded by BC016392)

Target Information

The protein encoded by this gene is a guanine nucleotide exchange factor (GEF) that plays a role in axon formation and neuronal polarization. The encoded protein displays GEF activity toward RAC1 and RAC3 Rho small GTPases but not toward CDC42. Several transcript variants encoding different isoforms have been found for this gene.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

EGFR ligand shifts the role of EGFR from oncogene to tumour suppressor in EGFR-amplified glioblastoma by suppressing invasion through BIN3 upregulation.

Nature cell biology

Guo G,Gong K,Beckley N,Zhang Y,Yang X,Chkheidze R,Hatanpaa KJ,Garzon-Muvdi T,Koduru P,Nayab A,Jenks J,Sathe AA,Liu Y,Xing C,Wu SY,Chiang CM,Mukherjee B,Burma S,Wohlfeld B,Patel T,Mickey B,Abdullah K,Youssef M,Pan E,Gerber DE,Tian S,Sarkaria JN,McBrayer SK,Zhao D,Habib AA

Mon Aug 01 00:00:00 UTC 2022

The WASH complex, an endosomal Arp2/3 activator, interacts with the Hermansky-Pudlak syndrome complex BLOC-1 and its cargo phosphatidylinositol-4-kinase type IIα.

Molecular biology of the cell

Ryder PV,Vistein R,Gokhale A,Seaman MN,Puthenveedu MA,Faundez V

Mon Jul 01 00:00:00 UTC 2013

The WASH complex, an endosomal Arp2/3 activator, interacts with the Hermansky-Pudlak syndrome complex BLOC-1 and its cargo phosphatidylinositol-4-kinase type IIα.

Molecular biology of the cell

Ryder PV,Vistein R,Gokhale A,Seaman MN,Puthenveedu MA,Faundez V

Mon Jul 01 00:00:00 UTC 2013

Bioinformatics

Protein Aliases: Dedicator of cytokinesis protein 7; protein moonlight

View more View less

Gene Aliases: 3110056M06Rik; DOCK7; EIEE23; Gm430; KIAA1771; m; ZIR2

View more View less

UniProt ID: (Human) Q96N67

View more View less

Entrez Gene ID: (Human) 85440, (Mouse) 67299, (Rat) 313388

View more View less

Function(s)

guanyl-nucleotide exchange factor activity Rac GTPase binding protein binding guanyl-nucleotide exchange factor

Process(es)

microtubule cytoskeleton organization small GTPase mediated signal transduction axonogenesis interkinetic nuclear migration neuron projection development positive regulation of peptidyl-serine phosphorylation establishment of neuroblast polarity regulation of neurogenesis activation of GTPase activity positive regulation of vascular associated smooth muscle cell migration hematopoietic progenitor cell differentiation multicellular organism development nervous system development cell differentiation pigmentation

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

Learn more

DOCK7 Polyclonal Antibody

DOCK7 Antibody (13000-1-AP) in WB

Product Details

13000-1-AP

Western Blot (WB)

Immunoprecipitation (IP)

Species Reactivity

Published species

Host/Isotype

Class

Type

Immunogen

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Shipping conditions

Product Specific Information

Target Information

Bioinformatics

Performance Guarantee

We're here to help

Your items have has been added!