Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Applications | Tested Dilution | Publications |
---|---|---|
Western Blot (WB) |
1:500-1:3,000 | View 2 publications 2 publications |
Immunohistochemistry (Paraffin) (IHC (P)) |
1:50-1:500 | - |
Immunohistochemistry (PFA fixed) (IHC (PFA)) |
1:20-1:200 | - |
Immunocytochemistry (ICC/IF) |
1:20-1:200 | View 1 publication 1 publication |
Immunoprecipitation (IP) |
0.5-4.0 µg | View 1 publication 1 publication |
Product Specifications | |
---|---|
Species Reactivity |
Human, Mouse, Rat |
Published species |
Human, Mouse, Rat |
Host/Isotype |
Rabbit / IgG |
Class |
Polyclonal |
Type |
Antibody |
Immunogen |
Dystrophin Fusion Protein Ag3408 (286-635 aa encoded by BC028720) |
Conjugate |
Unconjugated |
Form |
Liquid |
Concentration |
0.25 mg/mL |
Purification |
Antigen affinity chromatography |
Storage buffer |
PBS, pH 7.3, with 50% glycerol |
Contains |
0.02% sodium azide |
Storage conditions |
-20°C |
Immunogen sequence: YPMVEYCTP TTSGEDVRDF AKVLKNKFRT KRYFAKHPRM GYLPVQTVLE GDNMETPVTL INFWPVDSAP ASSPQLSHDD THSRIEHYAS RLAEMENSNG SYLNDSISPN ESIDDEHLLI QHYCQSLNQD SPLSQPRSPA QILISLESEE RGELERILAD LEEENRNLQA EYDRLKQQHE HKGLSPLPSP PEMMPTSPQS PRDAELIAEA KLLRQHKGRL EARMQILEDH NKQLESQLHR LRQLLEQPQA EAKVNGTTVS SPSTSLQRSD SSQPMLLRVV GSQTSDSMGE EDLLSPPQDT STGLEEVMEQ LNNSFPSSRG HNVGSLFHMA DDLGRAMESL VSVMTDEEGA E (286-635 aa encoded by BC028720)
Dystrophin is the 427kDa protein product of the DMB/BMD gene located on the X chromosome at position Xp21. Western blotting and immunohistochemistry are the two established methods for the detection of abnormalities of dystrophin expression in muscle biopsies. Dystrophin abnormalities are thought to occur in 100% of patients with DMD/BMD, although genetic abnormalities may only be detected in up to 65% of cases.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: apodystrophin-3; apodystrophin-I; Duchenne muscular dystrophy (DMD); Dystrophin; dystrophin Dp40; dystrophin Dp71a; dystrophin Dp71ab; dystrophin Dp71b; dystrophin, muscular dystrophy; GS1-19O24.1; Muscular dystrophy Duchenne and Becker types; OTTHUMP00000215592; X-linked muscular dystrophy
Gene Aliases: BMD; CMD3B; DMD; DNADMD1; Dp427; Dp71; DXS142; DXS164; DXS206; DXS230; DXS239; DXS268; DXS269; DXS270; DXS272; DXSmh7; DXSmh9; dys; mdx; MRX85; pke
UniProt ID: (Human) E7EQS5, (Mouse) P11531, (Rat) P11530
Entrez Gene ID: (Human) 1756, (Mouse) 13405, (Rat) 24907
Molecular Function:
ubiquitin-protein ligase
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn moreGet expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support