Product References
Hematopoietic Cell Kinase (HCK) Is a Player of the Crosstalk Between Hematopoietic Cells and Bone Marrow Niche Through CXCL12/CXCR4 Axis.
Frontiers in cell and developmental biology
Roversi FM,Bueno MLP,Pericole FV,Saad STO
44-654G was used in Western Blot to study the role of one SFK member, the Hematopoietic Cell Kinase (HCK), in CXCL12/CXCR4 pathway and its contribution to the AML pathogenesis.
Tue Apr 13 00:00:00 EDT 2021
Hematopoietic Cell Kinase (HCK) Is a Player of the Crosstalk Between Hematopoietic Cells and Bone Marrow Niche Through CXCL12/CXCR4 Axis.
Frontiers in cell and developmental biology
Roversi FM,Bueno MLP,Pericole FV,Saad STO
44-654G was used in Western Blot to study the role of one SFK member, the Hematopoietic Cell Kinase (HCK), in CXCL12/CXCR4 pathway and its contribution to the AML pathogenesis.
Tue Apr 13 00:00:00 EDT 2021
Role of thiocyanate in the modulation of myeloperoxidase-derived oxidant induced damage to macrophages.
Redox biology
Guo C,Davies MJ,Hawkins CL
44-654G was used in Western Blotting to provide further insight into the cellular pathways by which SCN- could exert protective effects on supplementation to decrease the development of chronic inflammatory diseases, such as atherosclerosis.
Tue Sep 01 00:00:00 EDT 2020
ZO-1 protein is required for hydrogen peroxide to increase MDCK cell paracellular permeability in an ERK 1/2-dependent manner.
American journal of physiology. Cell physiology
Bilal S,Jaggi S,Janosevic D,Shah N,Teymour S,Voronina A,Watari J,Axis J,Amsler K
Published figure using ERK1/ERK2 polyclonal antibody (Product # 44-654G) in Western Blot
Sat Sep 01 00:00:00 EDT 2018
Neonatal maternal deprivation impairs localized de novo activity-induced protein translation at the synapse in the rat hippocampus.
Bioscience reports
Ahmad F,Salahuddin M,Alsamman K,Herzallah HK,Al-Otaibi ST
44-654G was used in Western Blotting to elucidate the molecular mechanisms underlying the detrimental alterations in brain functions induced by early-life stress.
Fri Jun 29 00:00:00 EDT 2018
Development of MK-8353, an orally administered ERK1/2 inhibitor, in patients with advanced solid tumors.
JCI insight
Moschos SJ,Sullivan RJ,Hwu WJ,Ramanathan RK,Adjei AA,Fong PC,Shapira-Frommer R,Tawbi HA,Rubino J,Rush TS,Zhang D,Miselis NR,Samatar AA,Chun P,Rubin EH,Schiller J,Long BJ,Dayananth P,Carr D,Kirschmeier P,Bishop WR,Deng Y,Cooper A,Shipps GW,Moreno BH,Robert L,Ribas A,Flaherty KT
Published figure using ERK1/ERK2 polyclonal antibody (Product # 44-654G) in Western Blot
Thu Feb 22 00:00:00 EST 2018
Metformin exerts multitarget antileukemia activity in JAK2V617F-positive myeloproliferative neoplasms.
Cell death & disease
Machado-Neto JA,Fenerich BA,Scopim-Ribeiro R,Eide CA,Coelho-Silva JL,Dechandt CRP,Fernandes JC,Rodrigues Alves APN,Scheucher PS,Simões BP,Alberici LC,de Figueiredo Pontes LL,Tognon CE,Druker BJ,Rego EM,Traina F
Published figure using ERK1/ERK2 polyclonal antibody (Product # 44-654G) in Western Blot
Thu Feb 22 00:00:00 EST 2018
Hematopoietic cell kinase (HCK) is a potential therapeutic target for dysplastic and leukemic cells due to integration of erythropoietin/PI3K pathway and regulation of erythropoiesis: HCK in erythropoietin/PI3K pathway.
Biochimica et biophysica acta. Molecular basis of disease
Roversi FM,Pericole FV,Machado-Neto JA,da Silva Santos Duarte A,Longhini AL,Corrocher FA,Palodetto B,Ferro KP,Rosa RG,Baratti MO,Verjovski-Almeida S,Traina F,Molinari A,Botta M,Saad ST
44654G was used in western blot to characterize a new specific pharmacological hematopoietic cell kinase inhibitor
Wed Feb 01 00:00:00 EST 2017
WNK1 kinase balances T cell adhesion versus migration in vivo.
Nature immunology
Köchl R,Thelen F,Vanes L,Brazão TF,Fountain K,Xie J,Huang CL,Lyck R,Stein JV,Tybulewicz VL
Published figure using ERK1/ERK2 polyclonal antibody (Product # 44-654G) in Western Blot
Thu Sep 01 00:00:00 EDT 2016
WNK1 kinase balances T cell adhesion versus migration in vivo.
Nature immunology
Köchl R,Thelen F,Vanes L,Brazão TF,Fountain K,Xie J,Huang CL,Lyck R,Stein JV,Tybulewicz VL
Published figure using ERK1/ERK2 polyclonal antibody (Product # 44-654G) in Western Blot
Thu Sep 01 00:00:00 EDT 2016
Simultaneous Activation of Induced Heterodimerization between CXCR4 Chemokine Receptor and Cannabinoid Receptor 2 (CB2) Reveals a Mechanism for Regulation of Tumor Progression.
The Journal of biological chemistry
Coke CJ,Scarlett KA,Chetram MA,Jones KJ,Sandifer BJ,Davis AS,Marcus AI,Hinton CV
Published figure using ERK1/ERK2 polyclonal antibody (Product # 44-654G) in Western Blot
Fri May 06 00:00:00 EDT 2016
Melanocytes Affect Nodal Expression and Signaling in Melanoma Cells: A Lesson from Pediatric Large Congenital Melanocytic Nevi.
International journal of molecular sciences
Margaryan NV,Gilgur A,Seftor EA,Purnell C,Arva NC,Gosain AK,Hendrix MJ,Strizzi L
Published figure using ERK1/ERK2 polyclonal antibody (Product # 44-654G) in Western Blot
Tue Mar 22 00:00:00 EDT 2016
Effects of a novel Nodal-targeting monoclonal antibody in melanoma.
Oncotarget
Strizzi L,Sandomenico A,Margaryan NV,Focà A,Sanguigno L,Bodenstine TM,Chandler GS,Reed DW,Gilgur A,Seftor EA,Seftor RE,Khalkhali-Ellis Z,Leonardi A,Ruvo M,Hendrix MJ
44-654G was used in western blot to assess the use of 3D1 mAb for treating Nodal expressing cancers.
Tue Oct 27 00:00:00 EDT 2015
ANKHD1 silencing inhibits Stathmin 1 activity, cell proliferation and migration of leukemia cells.
Biochimica et biophysica acta
Machado-Neto JA,Lazarini M,Favaro P,de Melo Campos P,Scopim-Ribeiro R,Franchi Junior GC,Nowill AE,Lima PR,Costa FF,Benichou S,Olalla Saad ST,Traina F
44-654G was used in western blot to identify binding partners ANKHD1 in leukemia cells.
Sun Mar 01 00:00:00 EST 2015
Candidate tumor suppressor B-cell translocation gene 3 impedes neoplastic progression by suppression of AKT.
Cell death & disease
Cheng YC,Chen PH,Chiang HY,Suen CS,Hwang MJ,Lin TY,Yang HC,Lin WC,Lai PL,Shieh SY
44-654G was used in western blot to elucidate the tumor suppressor function of BTG3
Thu Jan 08 00:00:00 EST 2015
Silver and fullerene nanoparticles' effect on interleukin-2-dependent proliferation of CD4 (+) T cells.
Toxicology in vitro : an international journal published in association with BIBRA
Côté-Maurais G,Bernier J
44-654G was used in western blot to determine if nanoparticles inhibit IL-2-dependent T cell proliferation.
Mon Dec 01 00:00:00 EST 2014
Increased ERK and JNK activation and decreased ERK/JNK ratio are associated with long-term organ damage in patients with systemic lupus erythematosus.
Rheumatology (Oxford, England)
Bloch O,Amit-Vazina M,Yona E,Molad Y,Rapoport MJ
44-654G was used in western blot to test if extracellular signal-regulated kinase and c-Jun N-terminal kinase are associated with long-term organ damage in SLE patients.
Sun Jun 01 00:00:00 EDT 2014
Nuclear-localized focal adhesion kinase regulates inflammatory VCAM-1 expression.
The Journal of cell biology
Lim ST,Miller NL,Chen XL,Tancioni I,Walsh CT,Lawson C,Uryu S,Weis SM,Cheresh DA,Schlaepfer DD
Published figure using ERK1/ERK2 polyclonal antibody (Product # 44-654G) in Western Blot
Mon Jun 25 00:00:00 EDT 2012
Lyn is a redox sensor that mediates leukocyte wound attraction in vivo.
Nature
Yoo SK,Starnes TW,Deng Q,Huttenlocher A
44-654G was used in western blot to identify Lyn as a redox sensor that recruits neutrophils to wounds in zebrafish larvae.
Sun Nov 20 00:00:00 EST 2011
Alternative modes of GM-CSF receptor activation revealed using activated mutants of the common beta-subunit.
Blood
Perugini M,Brown AL,Salerno DG,Booker GW,Stojkoski C,Hercus TR,Lopez AF,Hibbs ML,Gonda TJ,D'Andrea RJ
Thu Apr 22 00:00:00 EDT 2010
Alternative modes of GM-CSF receptor activation revealed using activated mutants of the common beta-subunit.
Blood
Perugini M,Brown AL,Salerno DG,Booker GW,Stojkoski C,Hercus TR,Lopez AF,Hibbs ML,Gonda TJ,D'Andrea RJ
Thu Apr 22 00:00:00 EDT 2010
Increased ERK and JNK activities correlate with disease activity in patients with systemic lupus erythematosus.
Annals of the rheumatic diseases
Molad Y,Amit-Vasina M,Bloch O,Yona E,Rapoport MJ
44-654G was used in western blot to discuss the contribution of the p21ras/MAP kinase pathway to systemic lupus erythematosus
Fri Jan 01 00:00:00 EST 2010
The absence of caveolin-1 increases proliferation and anchorage- independent growth by a Rac-dependent, Erk-independent mechanism.
Molecular and cellular biology
Cerezo A,Guadamillas MC,Goetz JG,Sánchez-Perales S,Klein E,Assoian RK,del Pozo MA
44-654G was used in western blot to elucidate the mechanisms by which loss of Cav1 function promotes cancer cell growth
Tue Sep 01 00:00:00 EDT 2009
Molecular mechanisms involved in interleukin-4-induced human neutrophils: expression and regulation of suppressor of cytokine signaling.
Journal of leukocyte biology
Ratthé C,Pelletier M,Chiasson S,Girard D
Tue May 01 00:00:00 EDT 2007
The mitogen-activated protein kinases (MAPK) p38 and JNK are markers of tumor progression in breast carcinoma.
Gynecologic oncology
Davidson B,Konstantinovsky S,Kleinberg L,Nguyen MT,Bassarova A,Kvalheim G,Nesland JM,Reich R
Fri Sep 01 00:00:00 EDT 2006
Phospho-caveolin-1 mediates integrin-regulated membrane domain internalization.
Nature cell biology
del Pozo MA,Balasubramanian N,Alderson NB,Kiosses WB,Grande-García A,Anderson RG,Schwartz MA
Thu Sep 01 00:00:00 EDT 2005
Phospho-caveolin-1 mediates integrin-regulated membrane domain internalization.
Nature cell biology
del Pozo MA,Balasubramanian N,Alderson NB,Kiosses WB,Grande-García A,Anderson RG,Schwartz MA
Thu Sep 01 00:00:00 EDT 2005
TNF-alpha promotes a stop signal that inhibits neutrophil polarization and migration via a p38 MAPK pathway.
Journal of leukocyte biology
Lokuta MA,Huttenlocher A
Fri Jul 01 00:00:00 EDT 2005
Matrix metalloproteinases (MMP), EMMPRIN (extracellular matrix metalloproteinase inducer) and mitogen-activated protein kinases (MAPK): co-expression in metastatic serous ovarian carcinoma.
Clinical & experimental metastasis
Davidson B,Givant-Horwitz V,Lazarovici P,Risberg B,Nesland JM,Trope CG,Schaefer E,Reich R
Thu Dec 18 00:00:00 EST 2003