|ELISA (ELISA)||0.1-1 µg/ml|
|Gel Shift (GS)||Assay Dependent|
|Immunohistochemistry (Paraffin) (IHC (P))||1:10-1:100|
|Immunoprecipitation (IP)||2-5 µg/ml|
|Western Blot (WB)||1 µg/mL|
|Western Blot (WB)||See 21 publications below|
|Immunofluorescence (IF)||See 3 publications below|
|Miscellaneous PubMed (MISC)||See 4 publications below|
|Immunohistochemistry (IHC)||See 1 publications below|
|Tested Species reactivity||Dog, Human, Mouse, Rat|
|Published species reactivity||Rat , Human , Mouse , Xenopus|
|Host / Isotype||Mouse / IgG1, kappa|
|Immunogen||Synthetic Peptide (a.a. 324-345) corresponding to a segment near the C-terminus of rat ERK1.|
|Storage buffer||PBS, pH 7.4|
|Contains||0.1% sodium azide|
Extracellular signal-regulated kinase 2 (Erk2) is also known as mitogen activated protein kinase 2, microtubule-associated protein-2 kinase MAP kinase 2, p42-MAPK or EGF receptor T669 (ERT1). Mek2 activates Erk2 by phosphorylation of neighbouring threonine-183 and tyrosine-185 residues. Erk2, a serine-threonine kinase phosphorylates microtubule associated protein-2 and myelin basic protein. This kinase is an important proximal componant of the MAP kinase pathway involved in transmitting the signals from growth factors, neurotransmitters and hormones at the cell surface to the transcriptional events in the nucleus.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: ERK; ERK-1; ERK-2; ERK1; ERK2; ERT1; ERT2; Extracellular signal-regulated kinase 1; Extracellular signal-regulated kinase 2; extracellular signal-related kinase 1; extracellular-signal-regulated kinase 2; Insulin-stimulated MAP2 kinase; MAP kinase 1; MAP kinase 2; MAP kinase 3; MAP kinase isoform p42; MAP kinase isoform p44; MAPK; MAPK 1; MAPK 2; MAPK 3; MAPK2; Microtubule-associated protein 2 kinase; Mitogen activated protein kinase; Mitogen activated protein kinase 1; Mitogen activated protein kinase 2; mitogen-activated 3; Mitogen-activated protein kinase 1; Mitogen-activated protein kinase 2; Mitogen-activated protein kinase 3; MNK1; p41; p41mapk; p42 MAP Kinase; p42-MAPK; P42MAPK; p44 MAP Kinase; p44-ERK1; p44-MAPK; pp42/MAP kinase; PRKM1; PRKM2; protein tyrosine kinase ERK2
Gene Aliases: 9030612K14Rik; AA407128; AU018647; C78273; ERK; ERK-1; ERK-2; ERK1; ERK2; ERT1; ERT2; Esrk1; HS44KDAP; HUMKER1A; Mapk; MAPK1; MAPK2; MAPK3; MNK1; Mtap2k; p38; p40; p41; p41mapk; p42-MAPK; P42MAPK; p44; p44-ERK1; p44-MAPK; P44ERK1; P44MAPK; PRKM1; PRKM2; PRKM3
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