This Antibody was verified by KnockDown to ensure that the antibody binds to the antigen stated. View Details
MA5-13862 targets Ezrin in IHC (P), ICC, IP, IF, and WB applications and shows reactivity with Bovine, Hamster, Human, Marsupial, mouse, Non-human primate, and Rat samples.
The MA5-13862 immunogen is a recombinant fragment of human ezrin corresponding to aa 362-585.
Ezrin (also known as p81, 80K, or cytovillin) is a cytoplasmic protein enriched in microvilli and other cell surface structures. Its NH2-terminal domain is associated with the plasma membrane and the COOH-terminal domain with the cytoskeleton. Ezrin has an actin-binding capability. Ezrin is expressed in epithelial cells but not in mesenchymal cells. Ezrin is also expressed by certain epithelial tumors, such as renal cell adenocarcinomas. Ezrin serves as a tyrosine kinase substrate, and is phosphorylated in EGF-stimulated cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Cytovillin; cytovillin 2; epididymis secretory protein Li 105; Ezrin; p81; villin 2; villin 2 (ezrin); Villin-2
Gene Aliases: AW146364; BOS_138; CVIL; CVL; EZR; HEL-S-105; p81; R75297; VIL2