Sequence of this protein is as follows: QALGQDMVSP EATNSSSSSF SSPSSAGRHV RSYNHLQGDV RWRKLFSFTK YFLKIEKNGK VSGTKKENCP YSILEITSVE IGVVAVKAIN SNYYLAMNKK
FGF10 is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This protein exhibits mitogenic activity for keratinizing epidermal cells, but essentially no activity for fibroblasts, which is similar to the biological activity of FGF7. Studies of the mouse homolog of suggested that this gene is required for embryonic epidermal morphogenesis including brain development, lung morphogenesis, and initiation of lim bud formation. This protein is also implicated to be a primary factor in the process of wound healing.
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Protein Aliases: FGF; FGF-10; Fibroblast growth factor; Fibroblast growth factor 10; Keratinocyte growth factor 2; produced by fibroblasts of urinary bladder lamina propria
Gene Aliases: FGF10
UniProt ID: (Human) O15520
Entrez Gene ID: (Human) 2255