This Antibody was verified by Knockdown to ensure that the antibody binds to the antigen stated. View Details
MA5-15542 targets FOXA2 in IHC and WB applications and shows reactivity with Human samples.
The MA5-15542 immunogen is purified recombinant fragment of FOXA2 expressed in E. Coli.
MA5-15542 detects FOXA2 which has a predicted molecular weight of approximately 48kDa.
FOXA2 is a member of the forkhead class of DNA-binding proteins. These hepatocyte nuclear factors are transcriptional activators for liver-specific genes such as albumin and transthyretin. They also interact with chromatin. Similar family members in mice have roles in the regulation of metabolism and in the differentiation of the pancreas and liver. FOXA2 has been linked to sporadic cases of maturity-onset diabetes of the young. Transcript variants encoding different isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: FKHL20; Forkhead box protein A2; hepatic nuclear factor-3-beta; hepatocyte nuclear factor 3 beta (winged helix transcription factor); hepatocyte nuclear factor 3, beta; Hepatocyte nuclear factor 3-beta; HNF-3-beta; HNF-3B; MGC19807; RONU; TCF-3B; Transcription factor 3B; WHN
Gene Aliases: FOXA2; Hnf-3b; HNF3-beta; HNF3B; HNF3beta; Tcf-3b; TCF3B
Molecular Function: winged helix/forkhead transcription factor