|Tested species reactivity||Human|
|Host / Isotype||Mouse / IgG1|
|Immunogen||Human complement Factor H|
|Storage buffer||PBS with 4-5mg/ml BSA|
|Contains||0.02% sodium azide|
|Storage Conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
|Tested Applications||Dilution *|
|ELISA (ELISA)||Assay Dependent|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
MA5-17735 targets Factor H in ELISA applications and shows reactivity with Human samples.
The MA5-17735 immunogen is human complement Factor H.
Complement factor H1 (factor H1) is a plasma glycoprotein (139 kDa) and the secreted form of the protein is composed of 20 repetitive units of 60 amino acids, named short consensus repeats (SCR). Factor H1 is a central regulator of early alternative pathway activation by acting as a cofactor for factor I in the cleavage of C3b into iC3b. Factor H1 also competes with factor B for binding with C3b, inhibiting excessive alternative pathway activation. Complete (homozygous) factor H1 deficiency by genetic mutation has been rarely reported.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.