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Product Details
66322-1-IG
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Pig,
Rat
Published species
Not Applicable
Host/Isotype
Mouse
/ IgG2a
Class
Monoclonal
Type
Antibody
Clone
1E7B11
Immunogen
GAMT Fusion Protein Ag16778 (1-236 aa encoded by BC016760)
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MSAPSATPI FAPGENCSPA WGAAPAAYDA ADTHLRILGK PVMERWETPY MHALAAAASS KGGRVLEVGF GMAIAASKVQ EAPIDEHWII ECNDGVFQRL RDWAPRQTHK VIPLKGLWED VAPTLPDGHF DGILYDTYPL SEETWHTHQF NFIKNHAFRL LKPGGVLTYC NLTSWGELMK SKYSDITIMF EETQVPALLE AGFRRENIRT EVMALVPPAD CRYYAFPQMI TPLVTKG (1-236 aa encoded by BC016760)
Target Information
GAMT is a methyltransferase that converts guanidoacetate to creatine, using S-adenosylmethionine as the methyl donor. Defects in its gene have been implicated in neurologic syndromes and muscular hypotonia, probably due to creatine deficiency and accumulation of guanidinoacetate in the brain of affected individuals.The protein encoded by this gene is a methyltransferase that converts guanidoacetate to creatine, using S-adenosylmethionine as the methyl donor. Defects in this gene have been implicated in neurologic syndromes and muscular hypotonia, probably due to creatine deficiency and accumulation of guanidinoacetate in the brain of affected individuals. Two transcript variants encoding different isoforms have been described for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: epididymis secretory protein Li 20; guanidinoacetate methyltransferase; Guanidinoacetate N-methyltransferase
Gene Aliases: AA571402; CCDS2; GAMT; GMT; HEL-S-20; PIG2; Spintz1; TP53I2
UniProt ID: (Human) Q14353, (Mouse) O35969
Entrez Gene ID: (Human) 2593, (Pig) 100625146, (Mouse) 14431, (Rat) 25257
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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