Invitrogen

GCDFP-15 Monoclonal Antibody (23A3)

GCDFP-15 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

FIGURE: 1 / 1

GCDFP-15 Antibody (MA5-11633) in IHC (P)

Formalin-fixed, paraffin-embedded human skin stained with GCDFP15 antibody using peroxidase-conjugate and AEC chromogen. Note cytoplasmic staining of epithelial cells in the sweat glands.

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Product Details

MA5-11633

Applications

Tested Dilution

Publications

Immunohistochemistry (IHC)

View 10 publications 10 publications

Immunohistochemistry (Paraffin) (IHC (P))

1:30-1:60

View 1 publication 1 publication

Miscellaneous PubMed (Misc)

View 1 publication 1 publication

Product Specifications

Species Reactivity

Human, Rat

Published species

Human

Host/Isotype

Mouse / IgG2a, kappa

Class

Monoclonal

Type

Antibody

Clone

23A3

Immunogen

Recombinant protein encoding the excreted domain of human GCDFP15

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

Conc. Not Determined

Storage buffer

tissue culture supernatant

Contains

0.09% sodium azide

Storage conditions

4° C

Shipping conditions

Wet ice

RRID

AB_10985673

Product Specific Information

MA5-11633 targets GCDFP-15 in IHC (P) applications and shows reactivity with Human and Rat samples.

The MA5-11633 immunogen is recombinant protein encoding the excreted domain of human GCDFP15.

Target Information

Gross cystic disease of the breast is benign premenopausal disorder in which cysts are a predominant pathological lesion. These cysts appear to be formed from excessive apocrine cystic secretions. This fluid is composed of several glycoproteins including a unique 15kDa monomer protein, Gross Cystic Disease Fluid Protein-15 (GCDFP15). Cytosolic analysis of normal tissue specimens from all major organs has demonstrated GCDFP15 in apocrine epithelia, lacrimal, ceruminous and Moll's glands and in numerous serous cells of the submandibular, tracheal, bronchial, sublingual and minor salivary glands. GCDFP15 and prostate specific antigen are co-expressed in androgen receptor-positive breast tumours.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

Morphological features and mucin expression profile of breast carcinomas with signet-ring cell differentiation.

Pathology, research and practice

Bartosch C,Mendes N,Rios E,Rodrigues M,Eloy C,Reis CA,Amendoeira I

MA5-11633 was used in immunohistochemistry - paraffin section to characterize the morphological features and mucin expression profile of breast carcinomas with signet-ring cell differentiation.

Sat Aug 01 00:00:00 EDT 2015

A systematic analysis of commonly used antibodies in cancer diagnostics.

Histopathology

Gremel G,Bergman J,Djureinovic D,Edqvist PH,Maindad V,Bharambe BM,Khan WA,Navani S,Elebro J,Jirström K,Hellberg D,Uhlén M,Micke P,Pontén F

MA5-11633 was used in immunohistochemistry to perform a systematic study of the diagnostic power of a range of antibodies commonly used in the diagnosis of cancer

Wed Jan 01 00:00:00 EST 2014

Immunohistochemistry in the differential diagnostics of primary lung cancer: an investigation within the Southern Swedish Lung Cancer Study.

American journal of clinical pathology

Brunnström H,Johansson L,Jirström K,Jönsson M,Jönsson P,Planck M

MA5-11633 was used in immunohistochemistry to study the diagnostic value of a range of immunohistochemical markers in distinguishing different types of primary lung cancer

Mon Jul 01 00:00:00 EDT 2013

Amplification of the prolactin receptor gene in mammary lobular neoplasia.

Breast cancer research and treatment

Tran-Thanh D,Arneson NC,Pintilie M,Deliallisi A,Warren KS,Bane A,Done SJ

MA5-11633 was used in immunohistochemistry to study amplification of the prolactin receptor gene in mammary neoplasia.

Fri Jul 01 00:00:00 EDT 2011

Sclerosing polycystic adenosis of the parotid gland: report of a bifocal, paucicystic variant with ductal carcinoma in situ and pronounced stromal distortion mimicking invasive carcinoma.

Head and neck pathology

Petersson F,Tan PH,Hwang JS

MA5-11633 was used in immunohistochemistry to report a rare clinical case of sclerosing polycystic adenosis of the parotid gland

Wed Jun 01 00:00:00 EDT 2011

The role of immunohistochemistry in discriminating primary from secondary extramammary Paget disease.

The American Journal of dermatopathology

Perrotto J,Abbott JJ,Ceilley RI,Ahmed I

MA5-11633 was used in immunohistochemistry to investigate the usefulness of immunohistochemistry for extramammary Paget disease discrimination

Thu Apr 01 00:00:00 EDT 2010

Metastasis to the breast from an adenocarcinoma of the lung with extensive micropapillary component: a case report and review of the literature.

Diagnostic pathology

Maounis N,Chorti M,Legaki S,Ellina E,Emmanouilidou A,Demonakou M,Tsiafaki X

MA5-11633 was used in immunohistochemistry to report on a case of metastasis to the breast from an adenocarcinoma of the lung

Fri Dec 17 00:00:00 EST 2010

Apocrine carcinomas of the breast in Turkish women: hormone receptors, c-erbB-2 and p53 immunoexpression.

Pathology, research and practice

Kaya H,Bozkurt SU,Erbarut I,Djamgoz MB

MA5-11633 was used in immunohistochemistry to perform immunohistochemical studies of apocrine carcinomas in Turkish women with breast cancer

Thu Aug 21 00:00:00 EDT 2008

Clinocopathologic and immunohistochemical findings of multiple genital leiomyomas and mammary adenocarcinomas in a bitch.

Reproduction in domestic animals = Zuchthygiene

Ozmen O,Haligur M,Kocamuftuoglu M

MA5-11633 was used in immunohistochemistry to examine a case of canine multiple genital leiomyomas and mammary adenocarcinomas

Sun Jun 01 00:00:00 EDT 2008

An unusual apocrine carcinoma on the forehead.

The American Journal of dermatopathology

Misago N,Ohkawa T,Narisawa Y

MA5-11633 was used in immunohistochemistry to report on a case of unusual apocrine carcinoma of the forehead

Wed Aug 01 00:00:00 EDT 2007

Clear cell papulosis of the skin: a case report from Singapore.

Archives of pathology & laboratory medicine

Kumarasinghe SP,Chin GY,Kumarasinghe MP

MA5-11633 was used in immunohistochemistry to report on a case of clear cell papulosis of the skin

Mon Nov 01 00:00:00 EST 2004

Cloning, sequence and expression of human interleukin-2 receptor.

Nature

Cosman D,Cerretti DP,Larsen A,Park L,March C,Dower S,Gillis S,Urdal D

MA5-11633 was used to clone and characterize the IL-2 receptor from HUT-102 messenger RNA

Wed Feb 20 00:00:00 EST 1985

Bioinformatics

Protein Aliases: gcdfp 15; GCDFP-15; gp17; Gross cystic disease fluid protein 15; HGNC:8993; Prolactin-induced protein; Prolactin-inducible protein; Prolactin-inducible protein homolog; SABP; Secretory actin-binding protein

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Gene Aliases: GCDFP-15; GCDFP15; GPIP4; PIP

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UniProt ID: (Human) P12273, (Rat) O70417

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Entrez Gene ID: (Human) 5304, (Rat) 64673

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Function(s)

glycoprotein binding actin binding aspartic-type endopeptidase activity protein binding IgG binding protein dimerization activity

Process(es)

detection of chemical stimulus involved in sensory perception of bitter taste retina homeostasis regulation of immune system process proteolysis positive regulation of gene expression negative regulation of T cell apoptotic process transmembrane transport

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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GCDFP-15 Monoclonal Antibody (23A3)

GCDFP-15 Antibody (MA5-11633) in IHC (P)

Product Details

MA5-11633

Immunohistochemistry (IHC)

Immunohistochemistry (Paraffin) (IHC (P))

Miscellaneous PubMed (Misc)

Species Reactivity

Published species

Host/Isotype

Class

Type

Clone

Immunogen

Conjugate

Form

Concentration

Storage buffer

Contains

Storage conditions

Shipping conditions

RRID

Product Specific Information

Target Information

Bioinformatics

Performance Guarantee

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