Search Thermo Fisher Scientific
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Product Details
66012-1-IG
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Pig,
Rabbit,
Rat
Published species
Not Applicable
Host/Isotype
Mouse
/ IgG2a
Class
Monoclonal
Type
Antibody
Clone
5A11F8
Immunogen
GEFT Fusion Protein Ag10819 (1-349 aa encoded by BC012860)
Conjugate
Unconjugated
Form
Liquid
Concentration
1.34 mg/mL
Purification
Protein A
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Product Specific Information
Immunogen sequence: MLEPALATG EELPELTLLT TLLEGPGDKT QPPEEETLSQ APESEEEQKK KALERSMYVL SELVETEKMY VDDLGQIVEG YMATMAAQGV PESLRGRDRI VFGNIQQIYE WHRDYFLQEL QRCLKDPDWL AQLFIKHERR LHMYVVYCQN KPKSEHVVSE FGDSYFEELR QQLGHRLQLN DLLIKPVQRI MKYQLLLKDF LKYYNRAGMD TADLEQAVEV MCFVPKRCND MMTLGRLRGF EGKLTAQGKL LGQDTFWVTE PEAGGLLSSR GRERRVFLFE QIIIFSEALG GGVRGGTQPG YVYKNSIKVS CLGLEGNLQG DPCRFALTSR GPEGGIQRYV LQAADPAISQ (1-349 aa encoded by BC012860)
Target Information
The Rho family of small GTPases act as molecular switches to control a wide range of cellular processes. Guanine nucleotide exchange factors (GEFs), like GEFT, activate Rho GTPases by accelerating GDP/GTP exchange. The Rho family of small GTPases act as molecular switches to control a wide range of cellular processes. Guanine nucleotide exchange factors (GEFs), like GEFT, activate Rho GTPases by accelerating GDP/GTP exchange (Souchet et al., 2002 ).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Guanine nucleotide exchange factor GEFT; p63RhoGEF; RAC/CDC42 exchange factor; Rac/Cdc42/Rho exchange factor GEFT; Rho guanine nucleotide exchange factor (GEF) 25; Rho guanine nucleotide exchange factor 25; RhoA/RAC/CDC42 exchange factor; RhoA/Rac/Cdc42 guanine nucleotide exchange factor GEFT
Gene Aliases: 2410008H17Rik; ARHGEF25; D10Ertd610e; GEFT; p63RhoGEF
UniProt ID: (Human) Q86VW2, (Mouse) Q9CWR0, (Rat) Q6P720
Entrez Gene ID: (Rabbit) 100339852, (Pig) 100517400, (Human) 115557, (Mouse) 52666, (Rat) 314904
Molecular Function:
guanyl-nucleotide exchange factor
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support