Infection with specific types of HPV has been associated with an increased risk of developing cervical neoplasia. HPV types 6 and 11 have been associated with relatively benign diseases such as genital warts but types 16 and 18 are strongly associated with cervical, vaginal, and vulvar malignancies. E7-driven degradation of pRb may be involved in cervical tumorigenesis in humans.
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Protein Aliases: HPV E7; HPV-18; HPV18; human papillomavirus