|Tested species reactivity||Human, Mouse, Rat|
|Published species reactivity||Not Applicable|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Recombinant fragment corresponding to a region within amino acids 1 and 177 of IL1ra antagonist (Uniprot ID#P18510)|
|Purification||Antigen affinity chromatography|
|Storage buffer||0.1M tris glycine, pH 7, with 10% glycerol|
|Storage Conditions||-20° C, Avoid Freeze/Thaw Cycles|
|Tested Applications||Dilution *|
|Immunohistochemistry (Paraffin) (IHC (P))||1:100-1:1000|
|Western Blot (WB)||1:500-1:3000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
|Miscellaneous PubMed (MISC)||See 1 publications below|
PA5-21776 targets IL-1ra in ICC, IF, IHC (P), and WB applications and shows reactivity with Human, mouse and rat samples.
The PA5-21776 immunogen is recombinant protein fragment contain a sequence corresponding to a region within amino acids 1 and 177 (P18510) of IL1 Receptor antagonist.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
|Not Applicable||Not Cited||
Squamous metaplasia amplifies pathologic epithelial-mesenchymal interactions in COPD patients.
PA5-21776 was used in immunocytochemistry, immunohistochemistry, and western blot to investigate the relation between chronic obstructive pulmonary disease and squamous metaplasia
|Araya J,Cambier S,Markovics JA,Wolters P,Jablons D,Hill A,Finkbeiner W,Jones K,Broaddus VC,Sheppard D,Barzcak A,Xiao Y,Erle DJ,Nishimura SL||The Journal of clinical investigation (117:3551)||2007|