MA5-15883 targets IRAK4 in FACS, IHC, and WB applications and shows reactivity with Human, mouse, and Non-human primate samples.
The MA5-15883 immunogen is purified recombinant fragment of human IRAK4 expressed in E. Coli. .
MA5-15883 detects IRAK4 which has a predicted molecular weight of approximately 52kDa.
This gene encodes a kinase that activates NF-kappaB in both the Toll-like receptor (TLR) and T-cell receptor (TCR) signaling pathways. The protein is essential for most innate immune responses. Mutations in this gene result in IRAK4 deficiency and recurrent invasive pneumococcal disease. Multiple transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Interleukin-1 receptor-associated kinase 4; IPD1; IRAK-4; NY-REN-64; REN64; Renal carcinoma antigen NY-REN-64
Gene Aliases: 8430405M07Rik; 9330209D03Rik; IPD1; IRAK-4; IRAK4; NY-REN-64; REN64