MA5-15672 targets KLF4 in IHC and WB applications and shows reactivity with Human samples.
The MA5-15672 immunogen is purified recombinant fragment of human KLF4 (Amino Acid: 2-470) expressed in E. Coli.
MA5-15672 detects KLF4 which has a predicted molecular weight of approximately 55kDa.
This gene encodes a member of the membrane-spanning 4A gene family. Members of this nascent protein family are characterized by common structural features and similar intron/exon splice boundaries and display unique expression patterns among hematopoietic cells and nonlymphoid tissues. This gene encodes a B-lymphocyte surface molecule which plays a role in the development and differentiation of B-cells into plasma cells. This family member is localized to 11q12, among a cluster of family members. Alternative splicing of this gene results in two transcript variants which encode the same protein.
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Protein Aliases: endothelial Kruppel-like zinc finger protein; Epithelial zinc finger protein EZF; EZF; GKLF; gut Kruppel-like factor; Gut-enriched krueppel-like factor; KLF4; Krueppel-like factor 4; Kruppel-like factor 4 (gut)
Gene Aliases: EZF; GKLF; KLF4
UniProt ID: (Human) O43474
Entrez Gene ID: (Human) 9314