OriGene

KRT20 Monoclonal Antibody (UMAB172), UltraMAB™

Product Image Gallery

KRT20 Antibody in Immunohistochemistry (Paraffin) (IHC (P)) — Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human colon tissue using anti-KRT20 mouse monoclonal antibody. (UM800065; heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120°C for 3min)

KRT20 Antibody in Western Blot (WB) — Western blot of human tissue lysates (15 µg) from 10 different tissues (1: Testis, 2: Omentum, 3: Uterus, 4: Breast, 5: Brain, 6: Liver, 7: Ovary, 8: Thyroid, 9: Colon, 10: Spleen). Dilution: 1:500.

KRT20 Antibody in Peptide array (ARRAY) — OriGene overexpression protein microarray chip was immunostained with UltraMAB anti-KRT20 mouse monoclonal antibody (UM800065). The positive reactive proteins are highlighted with two red arrows in the enlarged subarray. All the positive controls spotted in this subarray are also labeled for clarification.

Product Details

UM800065

Applications	Tested Dilution	Publications
Immunohistochemistry (Paraffin) (IHC (P))	1:100-1:200	-
Miscellaneous PubMed (Misc)	-	View 5 publications 5 publications

Product Specifications
Species Reactivity	Human
Published species	Not Applicable
Host/Isotype	Mouse / IgG2a
Class	Monoclonal
Type	Antibody
Clone	UMAB172
Immunogen	Full length human recombinant protein of human KRT20 produced in E.coli. View antigen
Conjugate	Unconjugated
Form	liquid
Concentration	0.5-1 mg/mL
Purification	Affinity chromatography
Storage buffer	PBS with 1% BSA, 50% glycerol
Contains	0.02% sodium azide
Storage conditions	-20° C, Avoid Freeze/Thaw Cycles

Target Information

The protein encoded by this gene is a member of the keratin family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. The type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains. This cytokeratin is a major cellular protein of mature enterocytes and goblet cells and is specifically expressed in the gastric and intestinal mucosa. The type I cytokeratin genes are clustered in a region of chromosome 17q12-q21.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

Clinicopathologic study on a rare variant of ameloblastoma with basal cell features.

Oral diseases

You Z,Sun L,Yan X,Zhang J,Du J,Li T,Zhao H

Mon Apr 01 00:00:00 EDT 2019

Expression and clinical significance of ubiquitin‑specific‑processing protease 34 in diffuse large B‑cell lymphoma.

Molecular medicine reports

Li C,Huang L,Lu H,Wang W,Chen G,Gu Y,Zhou Q,Peng Z,Feng Z

Thu Nov 01 00:00:00 EDT 2018

Endometriosis-associated recto-sigmoid cancer: a case report.

BMC cancer

Li N,Zhou W,Zhao L,Zhou J

Thu Sep 20 00:00:00 EDT 2018

Hemophagocytic lymphohistiocytosis presenting with annular erythema multiforme-like eruptions in a patient with angioimmunoblastic T cell lymphoma: A case report.

Experimental and therapeutic medicine

Zhang L,Tong C,Tan Y,Peng S,He Y,Wang T

Sat Sep 01 00:00:00 EDT 2018

Immunohistochemical Evaluation of Peri-Implant Soft Tissues around Machined and Direct Metal Laser Sintered (DMLS) Healing Abutments in Humans.

International journal of environmental research and public health

Mangano C,Mangano FG,Shibli JA,Roth LA,d' Addazio G,Piattelli A,Iezzi G

Mon Jul 30 00:00:00 EDT 2018

Bioinformatics

Protein Aliases: CK-20; cytokeratin 20; Cytokeratin-20; K20; keratin 20, type I; Keratin, type I cytoskeletal 20; Keratin-20; MGC35423; Protein IT

Gene Aliases: CD20; CK-20; CK20; K20; KRT20; KRT21

UniProt ID: (Human) P35900

Entrez Gene ID: (Human) 54474

Function(s)

apoptotic process cellular response to stress intermediate filament organization regulation of protein secretion

Process(es)

structural constituent of cytoskeleton protein binding