Invitrogen

Ki-67 Monoclonal Antibody (SolA15), eBioscience™

Advanced Verification

This Antibody was verified by Cell treatment to ensure that the antibody binds to the antigen stated.

40 Published Figures

266 References

View all (164) Ki-67 antibodies

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Datasheet

Protocols

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Ki-67 Antibody in Immunocytochemistry (ICC/IF) — Immunofluorescence analysis of Ki67 was performed using 70% confluent log phase HeLa cells serum starved for 36 Hrs followed by serum release for 6 Hrs. The cells were fixed with 4% Paraformaldehyde for 10 minutes, permeabilized with 0.1% Triton™ X-100 for 10 minutes, and blocked with 2% BSA for 10 minutes at room temperature. The cells were labeled with Ki-67 Monoclonal Antibody (SolA15), eBioscience™ (Product # 14-5698-82) at 5 µg/mL in 0.1% BSA, incubated at 4 degree celsius overnight and then labeled with Goat anti-Rat IgG (H+L) Cross-Adsorbed Secondary Antibody, Alexa Fluor 488 (Product # A1-1006, 1:2000 dilution) for 45 minutes at room temperature (Panel a: Green). Nuclei (Panel b: Blue) were stained with SlowFade® Gold Antifade Mountant with DAPI (Product # S36938). F-actin (Panel c: Red) was stained with Rhodamine Phalloidin (Product # R415, 1:300). Panel d represents the merged image showing nuclear localization. Panel e represents serum starved cells with reduced signal. Panel f represents control cells with no primary antibody to assess background. The images were captured at 60X magnification.

Ki-67 Antibody in Immunohistochemistry (IHC) — Immunofluorescent analysis was performed with formalin-fixed paraffin embedded mouse stomach tumor sections. The slides were de-paraffinization and undergo antigen retrieval in TE pH9. The sections were blocked with 5% normal donkey serum in PBS for an hour, then incubated with the Rat anti-Ki67 antibody (Product # 14-5698-80) diluted 1:200 overnight. The slides were then washed three times with TBS, and incubated with the CY3 conjugated donkey anti-rat Cy3 secondary antibody for 1.5 hours. Finally the slides were counterstained with Hoechst (Product # 62249) diluted 1:5000 before mounting in Prolong Gold anti-fad mounting media (Product # P36931). Images were acquired using a confocal microscope. The positive and negative images show sections with and without the primary antibody respectively, acquired with the same imaging parameters. Data courtesy of Antibody Data Exchange Program.

Ki-67 Antibody — Immunofluorescence analysis of Ki67 was performed using 70% confluent log phase HeLa cells serum starved for 36 Hrs followed by serum release for 6 Hrs. The cells were fixed with 4% Paraformaldehyde for 10 minutes, permeabilized with 0.1% Triton™ X-100 for 10 minutes, and blocked with 2% BSA for 10 minutes at room temperature. The cells were labeled with Ki-67 Monoclonal Antibody (SolA15), eBioscience™ (Product # 14-5698-82) at 5 µg/ml in 0.1% BSA, incubated at 4 degree celsius overnight and then labeled with Goat anti-Mouse IgG (H+L) Superclonal™ Recombinant Secondary Antibody, Alexa Fluor® 488 conjugate (Product # A28175), (1:2000 dilution) for 45 minutes at room temperature (Panel a: Green). Nuclei (Panel b: Blue) were stained with SlowFade® Gold Antifade Mountant with DAPI (Product # S36938). F-actin (Panel c: Red) was stained with Rhodamine Phalloidin (Product # R415 , 1:300). Panel d represents the merged image showing Cytoplasmic localization. Panel e represents HeLa cells serum starved for 36 Hrs with reduced signal. Panel f represents control cells with no primary antibody to assess background. The images were captured at 60X magnification. {TM}

Ki-67 Antibody in Immunocytochemistry, Flow Cytometry (ICC/IF, Flow) — Figure 5. mTORC1 inhibition fails to drive activated SSC accumulation and early progenitor depletion in the absence of intercellular bridges (A and B) WM-IIF of PLZF (green, spermatogonia), RARgamma (red, late progenitors), SOX3 (white, early/late progenitors) or KIT (white, differentiating spermatogonia), and Ki67 (blue, proliferation) in seminiferous tubules from P36 Tex14 -/- mice. Arrowhead, quiescent SSCs (PLZF+/SOX3-/RARgamma/Ki67-) or early progenitors (PLZF+/KIT-/RARgamma-/Ki67-); arrow, activated SSCs (PLZF+/SOX3-/RARgamma-/Ki67+) or early progenitors (PLZF+/KIT-/RARgamma-/Ki67+); circle, early progenitors (PLZF+/SOX3+/RARgamma-/Ki67+); asterisk, late progenitors (PLZF+/SOX3+ or KIT-/RARgamma+/Ki67-). Scale bar, 20 mum. (C) Proportion of SSCs (KIT-/PLZF low /SOX3 low /RARgamma low ), early progenitors (KIT-/PLZF low /SOX3 high /RARgamma low ), and late progenitors (KIT-/PLZF high /SOX3 high /RARgamma high ) in seminiferous tubule cells from control (n = 3) and rapamycin-treated (n = 3) Tex14 -/- mice at P36 (see controls in Figure S3J ). Data are mean +- SEM. (D) Ki67 staining intensity in SSCs (KIT-/PLZF low /SOX3 low /RARgamma low ), early progenitors (KIT-/PLZF low /SOX3 high /RARgamma low ), and late progenitors (KIT-/PLZF high /SOX3 high /RARgamma high ) in seminiferous tubule cells from Tex14 +/- , Tex14 -/- , and rapamycin-treated Tex14 -/- mice (n = 3 each) at P36 (see controls in Figure S3J ). Data are mean +- SEM. Two-tailed Student''s t test (***p < 0.001)

Ki-67 Antibody in Immunocytochemistry, Immunohistochemistry (ICC/IF, IHC) — Figure 4 SARS-CoV-2 Infection Induces Loss of Surfactants and AT2 Death (A) Schematic for SARS-CoV-2-GFP infection in human alveolospheres. Alveolospheres were cultured in SFFF medium, infected with SARS-CoV-2 virus, and collected for histological analysis. (B) Quantification of the percentage of SARS-CoV-2-infected alveolospheres. (C) Immunostaining for GFP (green), SFTPC (red), and SARS (gray) (top panel) and GFP (green) and SFTPB (red) (bottom panel) in control, ""low,"" and ""high"" SARS-CoV-2-GFP-infected human lung alveolospheres at 72 h post-infection. Scale bar: 50 mum. (D) Quantification of low-infected (1-10 SARS-CoV-2 + cells) and high-infected (10 or more SARS-CoV-2 + cells) alveolospheres. (E) Quantification of SFTPC + cells in uninfected control and SARS - and SARS + cells in virus-infected alveolospheres. (F) Immunostaining for GFP (green) in combination with the apoptotic marker active caspase 3 (red) and proliferation marker Ki67 (gray) in control and SARS-CoV-2-GFP-infected alveolospheres. Scale bar: 30 mum. (G and H) Quantification of active caspase-3 (CASP3) + (G) and Ki67 + (H) cells in uninfected control (gray), SARS-CoV-2 - cells (blue), and SARS-CoV-2 + cells in infected alveolospheres. The white box in the merged image indicates the region of single-channel images. DAPI stains nuclei (blue). All quantification data are presented as mean +- SEM.

Ki-67 Antibody in Immunocytochemistry, Immunohistochemistry (Paraffin) (ICC/IF, IHC (P)) — Figure 1 (A) Scheme of experiments. (B) Representative image (at 10X, transmitted light microscopy) of GBM143 xenograft line cultured for 3 weeks in vitro in media indicated; cells were collected and orthotopically implanted into cranially irradiated mice 24 hrs post-irradiation (IR). (C) Representative Immunofluorescence (IF) images (at 4X, tiling) for hLamin A+C staining from 0 Gy and 20 Gy-IR mice coronal sections to assess tumor growth and invasion. (D) Top: Representative images (at 20X) show IF staining at tumor; and the dot-plot of single cell count for hLamin A+C and Ki67 staining. Bottom: Representative images (at 20X) show IF staining at center of corpus callosum, and dot-plot of single cell count for hLamin A+C. IH, ipsilateral hemisphere; CH, contralateral hemisphere; IR, irradiation. Statistical significance is represented as * p < 0.05.

Product Details

14-5698-82

Applications	Tested Dilution	Publications
Western Blot (WB)	-	View 1 publication 1 publication
Immunohistochemistry (IHC)	-	View 106 publications 106 publications
Immunohistochemistry (Paraffin) (IHC (P))	2.5-5 µg/mL	View 14 publications 14 publications
Immunohistochemistry (PFA fixed) (IHC (PFA))	-	View 3 publications 3 publications
Immunohistochemistry (Frozen) (IHC (F))	5 µg/mL	View 6 publications 6 publications
Immunocytochemistry (ICC/IF)	5 µg/mL	View 59 publications 59 publications
Flow Cytometry (Flow)	-	View 77 publications 77 publications

Product Specifications
Species Reactivity	Dog, Cynomolgus monkey, Human, Mouse, Non-human primate, Rat
Published species	Human, Mouse, Mustelid, Rat
Host/Isotype	Rat / IgG2a, kappa
Class	Monoclonal
Type	Antibody
Clone	SolA15
Conjugate	Unconjugated Alexa Fluor 488 Alexa Fluor 532 Alexa Fluor 660 Alexa Fluor 700 APC APC-eFluor 780 Biotin Brilliant UV 395 Brilliant UV 496 Brilliant UV 563 Brilliant UV 615 Brilliant UV 661 Brilliant UV 737 Brilliant UV 805 Brilliant Violet 421 Brilliant Violet 480 Brilliant Violet 711 Brilliant Violet 786 eFluor 450 eFluor 506 eFluor 570 eFluor 615 eFluor 660 FITC PE
Form	Liquid
Concentration	0.5 mg/mL
Purification	Affinity chromatography
Storage buffer	PBS, pH 7.2
Contains	0.09% sodium azide
Storage conditions	4° C
RRID	AB_10854564

Product Specific Information

Description: The monoclonal antibody SolA15 recognizes mouse and rat Ki-67, a 300 kDa nuclear protein. Ki-67 is present during all active phases of the cell cycle (G1, S, G2, and mitosis), but is absent from resting cells (G0). Ki-67 is detected within the nucleus during interphase but redistributes to the chromosomes during mitosis. Ki-67 is used as a marker for determining the growth fraction of a given population of cells. In studies of tumor cells, the "Ki-67 labeling index" refers to the number of Ki-67 positive cells within the population and this is used to predict outcome of particular cancer types. Ki-67 has been shown to interact with the DNA-bound protein chromobox protein homolog 3 (CBX3) (heterochromatin).

The SolA15 antibody also recognizes human, non-human primate and canine Ki-67.

Applications Reported: This SolA15 antibody has been reported for use in immunohistochemical staining of formalin-fixed paraffin embedded (FFPE) tissue sections and frozen (paraformaldehyde fixed) sections and immunocytochemistry (ICC).

Applications Tested: This SolA15 antibody has been tested by immunohistochemistry on formalin-fixed paraffin embedded mouse skin with high or low pH antigen retrieval and immunocytochemistry on fixed and permeabilized C2C12 cells at less than or equal to 5 µg/mL. It is recommended that this antibody be carefully titrated for optimal performance in the assay of interest.

Purity: Greater than 90%, as determined by SDS-PAGE.

Aggregation: Less than 10%, as determined by HPLC.

Filtration: 0.2 µm post-manufacturing filtered.

Target Information

Ki-67 is a nuclear protein that is expressed during various stages in the cell cycle, particularly during late G1, S, G2, and M phases. The protein has a forkhead associated domain (FHA) through which it associates with euchromatin at the perichromosomal layer, the centromeric heterochromatin, and the nucleolus. Ki-67 is shown to have a cell cycle dependent topographical distribution with perinucleolar expression at G1, expression in the nuclear matrix at G2, and expression on the chromosomes during M phase. Ki-67 is commonly used as a proliferation marker because it is not detected in G0 cells, but increases steadily from G1 through mitosis. Ki-67 antibodies are useful in establishing the cell growing fraction in neoplasms. In neoplastic tissues, the prognostic value is comparable to the tritiated thymidine-labelling index. The correlation between low Ki-67 index and histologically low-grade tumors is strong. Ki-67 is routinely used as a neuronal marker of cell cycling and proliferation.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

Inhibition of LncRNA Vof-16 expression promotes nerve regeneration and functional recovery after spinal cord injury.

Neural regeneration research

Zhang XM,Zeng LN,Yang WY,Ding L,Chen KZ,Fu WJ,Zeng SQ,Liang YR,Chen GH,Wu HF

Published figure using Ki-67 monoclonal antibody (Product # 14-5698-82) in Immunocytochemistry

Sat Jan 01 00:00:00 EST 2022

HDAC1/2 Control Proliferation and Survival in Adult Epidermis and Pre‒Basal Cell Carcinoma through p16 and p53.

The Journal of investigative dermatology

Zhu X,Leboeuf M,Liu F,Grachtchouk M,Seykora JT,Morrisey EE,Dlugosz AA,Millar SE

14-5698-82 was used in Immunohistochemistry to find that homozygous epidermal codeletion of Hdac1 and Hdac2 in adult mouse epidermis causes reduced basal cell proliferation, apoptosis, inappropriate differentiation, and eventual loss of Hdac1/2-null keratinocytes.

Sat Jan 01 00:00:00 EST 2022

IL-1beta promotes the age-associated decline of beta cell function.

iScience

Böni-Schnetzler M,Méreau H,Rachid L,Wiedemann SJ,Schulze F,Trimigliozzi K,Meier DT,Donath MY

Published figure using Ki-67 monoclonal antibody (Product # 14-5698-82) in Immunohistochemistry

Fri Nov 19 00:00:00 EST 2021

Gene Signatures Detect Damaged Liver Sinusoidal Endothelial Cells in Chronic Liver Diseases.

Frontiers in medicine

Verhulst S,van Os EA,De Smet V,Eysackers N,Mannaerts I,van Grunsven LA

Published figure using Ki-67 monoclonal antibody (Product # 14-5698-82) in Immunocytochemistry

Wed Nov 10 00:00:00 EST 2021

TWIK-1 BAC-GFP Transgenic Mice, an Animal Model for TWIK-1 Expression.

Cells

Kwon O,Yang H,Kim SC,Kim J,Sim J,Lee J,Hwang EM,Shim S,Park JY

Published figure using Ki-67 monoclonal antibody (Product # 14-5698-82) in Immunohistochemistry

Thu Oct 14 00:00:00 EDT 2021

NEIL3-deficiency increases gut permeability and contributes to a pro-atherogenic metabolic phenotype.

Scientific reports

Karlsen TR,Kong XY,Holm S,Quiles-Jiménez A,Dahl TB,Yang K,Sagen EL,Skarpengland T,S Øgaard JD,Holm K,Vestad B,Olsen MB,Aukrust P,Bjørås M,Hov JR,Halvorsen B,Gregersen I

Published figure using Ki-67 monoclonal antibody (Product # 14-5698-82) in Immunocytochemistry

Tue Oct 05 00:00:00 EDT 2021

Impairment of type H vessels by NOX2-mediated endothelial oxidative stress: critical mechanisms and therapeutic targets for bone fragility in streptozotocin-induced type 1 diabetic mice.

Theranostics

Hu XF,Xiang G,Wang TJ,Ma YB,Zhang Y,Yan YB,Zhao X,Wu ZX,Feng YF,Lei W

14-5698 was used in Immunohistochemistry-immunofluorescence to propose that the impairment of type H vessels by NOX2-mediated endothelial oxidative stress might be an important contributor to type 1 diabetes mellitus-induced osteopathy.

Thu Jul 29 00:00:00 EDT 2021

Developmental Role of Adenosine Kinase in the Cerebellum.

eNeuro

Gebril H,Wahba A,Zhou X,Lai T,Alharfoush E,DiCicco-Bloom E,Boison D

Published figure using Ki-67 monoclonal antibody (Product # 14-5698-82) in Immunohistochemistry

Fri Jul 02 00:00:00 EDT 2021

Notch Signaling between Cerebellar Granule Cell Progenitors.

eNeuro

Adachi T,Miyashita S,Yamashita M,Shimoda M,Okonechnikov K,Chavez L,Kool M,Pfister SM,Inoue T,Kawauchi D,Hoshino M

14-5698-82 was used in Immunohistochemistry to suggest that Notch signaling results in the proportional generation of two types of cells, immature and differentiating GCPs, which contributes to the well-organized differentiation of GCs.

Fri Jul 02 00:00:00 EDT 2021

Environmental enrichment preserves a young DNA methylation landscape in the aged mouse hippocampus.

Nature communications

Zocher S,Overall RW,Lesche M,Dahl A,Kempermann G

14-5698-82 was used in Immunohistochemistry to show that experiencing a stimulus-rich environment counteracts age-related DNA methylation changes in the hippocampal dentate gyrus of mice.

Wed Jun 23 00:00:00 EDT 2021

HIF-1α is necessary for activation and tumour-promotion effect of cancer-associated fibroblasts in lung cancer.

Journal of cellular and molecular medicine

Zhang Y,Bian Y,Wang Y,Wang Y,Duan X,Han Y,Zhang L,Wang F,Gu Z,Qin Z

14-5698-82 was used in Immunohistochemistry, Immunocytochemistry to find that hypoxia-inducible factor-1α (HIF-1α) is highly expressed in CAFs of human lung cancer tissues and mouse spontaneous lung tumour.

Tue Jun 01 00:00:00 EDT 2021

HIF-1α is necessary for activation and tumour-promotion effect of cancer-associated fibroblasts in lung cancer.

Journal of cellular and molecular medicine

Zhang Y,Bian Y,Wang Y,Wang Y,Duan X,Han Y,Zhang L,Wang F,Gu Z,Qin Z

Tue Jun 01 00:00:00 EDT 2021

Differential chromatin binding of the lung lineage transcription factor NKX2-1 resolves opposing murine alveolar cell fates in vivo.

Nature communications

Little DR,Lynch AM,Yan Y,Akiyama H,Kimura S,Chen J

14-5698-82 was used in Immunocytochemistry to report that the cell-type-specific function of NKX2-1 is attributed to its differential chromatin binding that is acquired or retained during development in coordination with partner transcriptional factors.

Tue May 04 00:00:00 EDT 2021

Adult neural stem cells have latent inflammatory potential that is kept suppressed by Tcf4 to facilitate adult neurogenesis.

Science advances

Shariq M,Sahasrabuddhe V,Krishna S,Radha S,Bellampalli R,Dwivedi A,Cheramangalam R,Reizis B,Hébert J,Ghosh HS

Published figure using Ki-67 monoclonal antibody (Product # 14-5698-82) in Immunohistochemistry (PFA fixed)

Sat May 01 00:00:00 EDT 2021

Adult neural stem cells have latent inflammatory potential that is kept suppressed by Tcf4 to facilitate adult neurogenesis.

Science advances

Shariq M,Sahasrabuddhe V,Krishna S,Radha S,Bellampalli R,Dwivedi A,Cheramangalam R,Reizis B,Hébert J,Ghosh HS

Published figure using Ki-67 monoclonal antibody (Product # 14-5698-82) in Immunohistochemistry (PFA fixed)

Sat May 01 00:00:00 EDT 2021

Environmental oxygen regulates astrocyte proliferation to guide angiogenesis during retinal development.

Development (Cambridge, England)

Perelli RM,O'Sullivan ML,Zarnick S,Kay JN

Published figure using Ki-67 monoclonal antibody (Product # 14-5698-82) in Immunohistochemistry

Sat May 01 00:00:00 EDT 2021

Environmental oxygen regulates astrocyte proliferation to guide angiogenesis during retinal development.

Development (Cambridge, England)

Perelli RM,O'Sullivan ML,Zarnick S,Kay JN

Published figure using Ki-67 monoclonal antibody (Product # 14-5698-82) in Immunohistochemistry

Sat May 01 00:00:00 EDT 2021

CYBB/NOX2 in conventional DCs controls T cell encephalitogenicity during neuroinflammation.

Autophagy

Keller CW,Kotur MB,Mundt S,Dokalis N,Ligeon LA,Shah AM,Prinz M,Becher B,Münz C,Lünemann JD

14-5698 was used in Immunohistochemistry to report that the nicotinamide adenine dinucleotide phosphate (NADPH) oxidase 2, also known as CYBB/NOX2, in conventional DCs (cDCs) regulates endocytosed MOG (myelin oligodendrocyte protein) antigen processing and supports MOG-antigen presentation to CD4+ T cells through LC3-associated phagocytosis (LAP).

Sat May 01 00:00:00 EDT 2021

Ten-eleven translocation protein 1 modulates medulloblastoma progression.

Genome biology

Kim H,Kang Y,Li Y,Chen L,Lin L,Johnson ND,Zhu D,Robinson MH,McSwain L,Barwick BG,Yuan X,Liao X,Zhao J,Zhang Z,Shu Q,Chen J,Allen EG,Kenney AM,Castellino RC,Van Meir EG,Conneely KN,Vertino PM,Jin P,Li J

Published figure using Ki-67 monoclonal antibody (Product # 14-5698-82) in Immunohistochemistry (Frozen)

Thu Apr 29 00:00:00 EDT 2021

Ten-eleven translocation protein 1 modulates medulloblastoma progression.

Genome biology

Published figure using Ki-67 monoclonal antibody (Product # 14-5698-82) in Immunohistochemistry (Frozen)

Thu Apr 29 00:00:00 EDT 2021

Delta-like 4 is required for pulmonary vascular arborization and alveolarization in the developing lung.

JCI insight

Xia S,Menden HL,Townley N,Mabry SM,Johnston J,Nyp MF,Heruth DP,Korfhagen T,Sampath V

Published figure using Ki-67 monoclonal antibody (Product # 14-5698-82) in Immunohistochemistry

Thu Apr 08 00:00:00 EDT 2021

Targeting Feedforward Loops Formed by Nuclear Receptor RORγ and Kinase PBK in mCRPC with Hyperactive AR Signaling.

Cancers

Zhang X,Huang Z,Wang J,Ma Z,Yang J,Corey E,Evans CP,Yu AM,Chen HW

Published figure using Ki-67 monoclonal antibody (Product # 14-5698-82) in Immunohistochemistry

Thu Apr 01 00:00:00 EDT 2021

CDCP1 promotes compensatory renal growth by integrating Src and Met signaling.

Life science alliance

Kajiwara K,Yamano S,Aoki K,Okuzaki D,Matsumoto K,Okada M

Published figure using Ki-67 monoclonal antibody (Product # 14-5698-82) in Immunohistochemistry

Thu Apr 01 00:00:00 EDT 2021

MicroRNA-384 inhibits nasopharyngeal carcinoma growth and metastasis via binding to Smad5 and suppressing the Wnt/β-catenin axis.

Cytotechnology

Zeng X,Liao H,Wang F

Published figure using Ki-67 monoclonal antibody (Product # 14-5698-82) in Immunohistochemistry

Thu Apr 01 00:00:00 EDT 2021

Single-cell atlas of early human brain development highlights heterogeneity of human neuroepithelial cells and early radial glia.

Nature neuroscience

Eze UC,Bhaduri A,Haeussler M,Nowakowski TJ,Kriegstein AR

14-5698-82 was used in Immunohistochemistry to provide a comprehensive molecular and spatial atlas of early stages of human brain and cortical development.

Thu Apr 01 00:00:00 EDT 2021

Field size effects on DNA damage and proliferation in normal human cell populations irradiated with X-ray microbeams.

Scientific reports

Ojima M,Ito A,Usami N,Ohara M,Suzuki K,Kai M

Published figure using Ki-67 monoclonal antibody (Product # 14-5698-82) in Immunocytochemistry

Fri Mar 26 00:00:00 EDT 2021

Field size effects on DNA damage and proliferation in normal human cell populations irradiated with X-ray microbeams.

Scientific reports

Ojima M,Ito A,Usami N,Ohara M,Suzuki K,Kai M

Published figure using Ki-67 monoclonal antibody (Product # 14-5698-82) in Immunocytochemistry

Fri Mar 26 00:00:00 EDT 2021

A booster dose enhances immunogenicity of the COVID-19 vaccine candidate ChAdOx1 nCoV-19 in aged mice.

Med (New York, N.Y.)

Silva-Cayetano A,Foster WS,Innocentin S,Belij-Rammerstorfer S,Spencer AJ,Burton OT,Fra-Bidó S,Le Lee J,Thakur N,Conceicao C,Wright D,Barrett J,Evans-Bailey N,Noble C,Bailey D,Liston A,Gilbert SC,Lambe T,Linterman MA

Published figure using Ki-67 monoclonal antibody (Product # 14-5698-82) in Immunohistochemistry

Fri Mar 12 00:00:00 EST 2021

Pax6 Lengthens G1 Phase and Decreases Oscillating Cdk6 Levels in Murine Embryonic Cortical Progenitors.

Frontiers in cellular neuroscience

Mi D,Manuel M,Huang YT,Mason JO,Price DJ

Published figure using Ki-67 monoclonal antibody (Product # 14-5698-82) in Flow Cytometry

Thu Mar 04 00:00:00 EST 2021

Dissecting phenotypic transitions in metastatic disease via photoconversion-based isolation.

eLife

Sela Y,Li J,Kuri P,Merrell AJ,Li N,Lengner C,Rompolas P,Stanger BZ

Published figure using Ki-67 monoclonal antibody (Product # 14-5698-82) in Immunohistochemistry

Tue Feb 23 00:00:00 EST 2021

Dissecting phenotypic transitions in metastatic disease via photoconversion-based isolation.

eLife

Sela Y,Li J,Kuri P,Merrell AJ,Li N,Lengner C,Rompolas P,Stanger BZ

Published figure using Ki-67 monoclonal antibody (Product # 14-5698-82) in Immunohistochemistry

Tue Feb 23 00:00:00 EST 2021

An mTORC1-dependent switch orchestrates the transition between mouse spermatogonial stem cells and clones of progenitor spermatogonia.

Cell reports

Suzuki S,McCarrey JR,Hermann BP

Published figure using Ki-67 monoclonal antibody (Product # 14-5698-82) in Flow Cytometry

Tue Feb 16 00:00:00 EST 2021

An mTORC1-dependent switch orchestrates the transition between mouse spermatogonial stem cells and clones of progenitor spermatogonia.

Cell reports

Suzuki S,McCarrey JR,Hermann BP

Published figure using Ki-67 monoclonal antibody (Product # 14-5698-82) in Flow Cytometry

Tue Feb 16 00:00:00 EST 2021

CAMSAP3 is required for mTORC1-dependent ependymal cell growth and lateral ventricle shaping in mouse brains.

Development (Cambridge, England)

Kimura T,Saito H,Kawasaki M,Takeichi M

14-5698-82 was used in Immunohistochemistry to suggest that CAMSAP3 supports mTORC1 signaling required for ependymal cell growth via MT network regulation, and, in turn, shaping of the lateral ventricles.

Fri Feb 05 00:00:00 EST 2021

Requirement of DNMT1 to orchestrate epigenomic reprogramming for NPM-ALK-driven lymphomagenesis.

Life science alliance

Redl E,Sheibani-Tezerji R,Cardona CJ,Hamminger P,Timelthaler G,Hassler MR,Zrimšek M,Lagger S,Dillinger T,Hofbauer L,Draganić K,Tiefenbacher A,Kothmayer M,Dietz CH,Ramsahoye BH,Kenner L,Bock C,Seiser C,Ellmeier W,Schweikert G,Egger G

Published figure using Ki-67 monoclonal antibody (Product # 14-5698-82) in Immunohistochemistry

Mon Feb 01 00:00:00 EST 2021

Heterogeneity of astrocytes: Electrophysiological properties of juxtavascular astrocytes before and after brain injury.

Glia

Götz S,Bribian A,López-Mascaraque L,Götz M,Grothe B,Kunz L

Published figure using Ki-67 monoclonal antibody (Product # 14-5698-82) in Immunocytochemistry

Mon Feb 01 00:00:00 EST 2021

Heterogeneity of astrocytes: Electrophysiological properties of juxtavascular astrocytes before and after brain injury.

Glia

Götz S,Bribian A,López-Mascaraque L,Götz M,Grothe B,Kunz L

Published figure using Ki-67 monoclonal antibody (Product # 14-5698-82) in Immunocytochemistry

Mon Feb 01 00:00:00 EST 2021

Heterogeneity of astrocytes: Electrophysiological properties of juxtavascular astrocytes before and after brain injury.

Glia

Götz S,Bribian A,López-Mascaraque L,Götz M,Grothe B,Kunz L

Published figure using Ki-67 monoclonal antibody (Product # 14-5698-82) in Immunocytochemistry

Mon Feb 01 00:00:00 EST 2021

Transcription factor old astrocyte specifically induced substance is a novel regulator of kidney fibrosis.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology

Yamamoto A,Morioki H,Nakae T,Miyake Y,Harada T,Noda S,Mitsuoka S,Matsumoto K,Tomimatsu M,Kanemoto S,Tanaka S,Maeda M,Conway SJ,Imaizumi K,Fujio Y,Obana M

14-5698 was used in Immunohistochemistry to identify and demonstrate that OASIS signalling is a novel regulator of kidney fibrosis.

Mon Feb 01 00:00:00 EST 2021

The stress kinase GCN2 does not mediate suppression of antitumor T cell responses by tryptophan catabolism in experimental melanomas.

Oncoimmunology

Sonner JK,Deumelandt K,Ott M,Thomé CM,Rauschenbach KJ,Schulz S,Munteanu B,Mohapatra S,Adam I,Hofer AC,Feuerer M,Opitz CA,Hopf C,Wick W,Platten M

Published figure using Ki-67 monoclonal antibody (Product # 14-5698-82) in Flow Cytometry

Tue Jan 12 00:00:00 EST 2021

Targeting Phosphatidylserine Enhances the Anti-tumor Response to Tumor-Directed Radiation Therapy in a Preclinical Model of Melanoma.

Cell reports

Budhu S,Giese R,Gupta A,Fitzgerald K,Zappasodi R,Schad S,Hirschhorn D,Campesato LF,De Henau O,Gigoux M,Liu C,Mazo G,Deng L,Barker CA,Wolchok JD,Merghoub T

Published figure using Ki-67 monoclonal antibody (Product # 14-5698-82) in Flow Cytometry

Tue Jan 12 00:00:00 EST 2021

Growth and metastasis of lung adenocarcinoma is potentiated by BMP4-mediated immunosuppression.

Oncoimmunology

Chen L,Yi X,Goswami S,Ahn YH,Roybal JD,Yang Y,Diao L,Peng D,Peng D,Fradette JJ,Wang J,Byers LA,Kurie JM,Ullrich SE,Qin FX,Gibbons DL

Published figure using Ki-67 monoclonal antibody (Product # 14-5698-82) in Flow Cytometry

Tue Jan 12 00:00:00 EST 2021

An in vivo model allowing continuous observation of human vascular formation in the same animal over time.

Scientific reports

Tsukada Y,Muramatsu F,Hayashi Y,Inagaki C,Su H,Iba T,Kidoya H,Takakura N

14-5698 was used in Immunohistochemistry-immunofluorescence to develop a human blood vessel model in mice for understanding human blood vessel formation mechanisms and the effects of drugs that target human blood vessels in vivo.

Tue Jan 12 00:00:00 EST 2021

CXCR4 Regulates Temporal Differentiation via PRC1 Complex in Organogenesis of Epithelial Glands.

International journal of molecular sciences

Kim J,Lee SW,Park K

Published figure using Ki-67 monoclonal antibody (Product # 14-5698-82) in Immunocytochemistry

Sun Jan 10 00:00:00 EST 2021

CXCR4 Regulates Temporal Differentiation via PRC1 Complex in Organogenesis of Epithelial Glands.

International journal of molecular sciences

Kim J,Lee SW,Park K

Published figure using Ki-67 monoclonal antibody (Product # 14-5698-82) in Immunocytochemistry

Sun Jan 10 00:00:00 EST 2021

Thrombospondin-2 spatiotemporal expression in skeletal fractures.

Journal of orthopaedic research : official publication of the Orthopaedic Research Society

Zondervan RL,Jenkins DC,Reicha JD,Hankenson KD

Published figure using Ki-67 monoclonal antibody (Product # 14-5698-82) in Immunocytochemistry

Fri Jan 01 00:00:00 EST 2021

Effect of cellular and ECM aging on human iPSC-derived cardiomyocyte performance, maturity and senescence.

Biomaterials

Ozcebe SG,Bahcecioglu G,Yue XS,Zorlutuna P

14-5698-82 was used in Immunocytochemistry to investigate the individual effects of cellular and environmental aging and identify the biochemical changes that occur upon cardiac aging.

Fri Jan 01 00:00:00 EST 2021

Changes in Liver Mechanical Properties and Water Diffusivity During Normal Pregnancy Are Driven by Cellular Hypertrophy.

Frontiers in physiology

Garczyńska K,Tzschätzsch H,Kühl AA,Morr AS,Lilaj L,Häckel A,Schellenberger E,Berndt N,Holzhütter HG,Braun J,Sack I,Guo J

Published figure using Ki-67 monoclonal antibody (Product # 14-5698-82) in Immunohistochemistry

Fri Dec 18 00:00:00 EST 2020

Cardiac fibroblast proliferation rates and collagen expression mature early and are unaltered with advancing age.

JCI insight

Wu R,Ma F,Tosevska A,Farrell C,Pellegrini M,Deb A

Published figure using Ki-67 monoclonal antibody (Product # 14-5698-82) in Flow Cytometry

Thu Dec 17 00:00:00 EST 2020

Aripiprazole reduces liver cell division.

PloS one

Pirc Marolt T,Kramar B,Bulc Rozman K,Šuput D,Milisav I

Published figure using Ki-67 monoclonal antibody (Product # 14-5698-82) in Immunocytochemistry

Tue Dec 08 00:00:00 EST 2020

Human Lung Stem Cell-Based Alveolospheres Provide Insights into SARS-CoV-2-Mediated Interferon Responses and Pneumocyte Dysfunction.

Cell stem cell

Katsura H,Sontake V,Tata A,Kobayashi Y,Edwards CE,Heaton BE,Konkimalla A,Asakura T,Mikami Y,Fritch EJ,Lee PJ,Heaton NS,Boucher RC,Randell SH,Baric RS,Tata PR

Published figure using Ki-67 monoclonal antibody (Product # 14-5698-82) in Immunocytochemistry

Thu Dec 03 00:00:00 EST 2020

Human Lung Stem Cell-Based Alveolospheres Provide Insights into SARS-CoV-2-Mediated Interferon Responses and Pneumocyte Dysfunction.

Cell stem cell

Katsura H,Sontake V,Tata A,Kobayashi Y,Edwards CE,Heaton BE,Konkimalla A,Asakura T,Mikami Y,Fritch EJ,Lee PJ,Heaton NS,Boucher RC,Randell SH,Baric RS,Tata PR

Published figure using Ki-67 monoclonal antibody (Product # 14-5698-82) in Immunocytochemistry

Thu Dec 03 00:00:00 EST 2020

Human Lung Stem Cell-Based Alveolospheres Provide Insights into SARS-CoV-2-Mediated Interferon Responses and Pneumocyte Dysfunction.

Cell stem cell

Katsura H,Sontake V,Tata A,Kobayashi Y,Edwards CE,Heaton BE,Konkimalla A,Asakura T,Mikami Y,Fritch EJ,Lee PJ,Heaton NS,Boucher RC,Randell SH,Baric RS,Tata PR

Published figure using Ki-67 monoclonal antibody (Product # 14-5698-82) in Immunocytochemistry

Thu Dec 03 00:00:00 EST 2020

CD103⁺ cDC1 and endogenous CD8⁺ T cells are necessary for improved CD40L-overexpressing CAR T cell antitumor function.

Nature communications

Kuhn NF,Lopez AV,Li X,Cai W,Daniyan AF,Brentjens RJ

Published figure using Ki-67 monoclonal antibody (Product # 14-5698-82) in Flow Cytometry

Wed Dec 02 00:00:00 EST 2020

Multimodal single-cell analysis reveals distinct radioresistant stem-like and progenitor cell populations in murine glioma.

Glia

Alexander J,LaPlant QC,Pattwell SS,Szulzewsky F,Cimino PJ,Caruso FP,Pugliese P,Chen Z,Chardon F,Hill AJ,Spurrell C,Ahrendsen D,Pietras A,Starita LM,Hambardzumyan D,Iavarone A,Shendure J,Holland EC

Published figure using Ki-67 monoclonal antibody (Product # 14-5698-82) in Immunohistochemistry

Tue Dec 01 00:00:00 EST 2020

Multimodal single-cell analysis reveals distinct radioresistant stem-like and progenitor cell populations in murine glioma.

Glia

Alexander J,LaPlant QC,Pattwell SS,Szulzewsky F,Cimino PJ,Caruso FP,Pugliese P,Chen Z,Chardon F,Hill AJ,Spurrell C,Ahrendsen D,Pietras A,Starita LM,Hambardzumyan D,Iavarone A,Shendure J,Holland EC

Published figure using Ki-67 monoclonal antibody (Product # 14-5698-82) in Immunohistochemistry

Tue Dec 01 00:00:00 EST 2020

Ferroptosis Mediates Cuprizone-Induced Loss of Oligodendrocytes and Demyelination.

The Journal of neuroscience : the official journal of the Society for Neuroscience

Jhelum P,Santos-Nogueira E,Teo W,Haumont A,Lenoël I,Stys PK,David S

14-5698-82 was used in Immunocytochemistry to show that giving mice (male) CZ in the diet induces rapid loss of OL in the corpus callosum by 2 d, accompanied by expression of several markers for ferroptosis, a relatively newly described form of iron-mediated cell death.

Wed Nov 25 00:00:00 EST 2020

Mapping endothelial-cell diversity in cerebral cavernous malformations at single-cell resolution.

eLife

Orsenigo F,Conze LL,Jauhiainen S,Corada M,Lazzaroni F,Malinverno M,Sundell V,Cunha SI,Brännström J,Globisch MA,Maderna C,Lampugnani MG,Magnusson PU,Dejana E

14-5698-82 was used in Immunocytochemistry to comprehensively characterize subclasses of brain endothelial cells (ECs) under both normal conditions and after deletion of Pdcd10 (Ccm3) in a mouse model of CCM.

Tue Nov 03 00:00:00 EST 2020

Administration of all-trans retinoic acid after experimental traumatic brain injury is brain protective.

British journal of pharmacology

Hummel R,Ulbrich S,Appel D,Li S,Hirnet T,Zander S,Bobkiewicz W,Gölz C,Schäfer MKE

Published figure using Ki-67 monoclonal antibody (Product # 14-5698-82) in Immunohistochemistry

Sun Nov 01 00:00:00 EDT 2020

Regeneration of the pulmonary vascular endothelium after viral pneumonia requires COUP-TF2.

Science advances

Zhao G,Weiner AI,Neupauer KM,de Mello Costa MF,Palashikar G,Adams-Tzivelekidis S,Mangalmurti NS,Vaughan AE

Published figure using Ki-67 monoclonal antibody (Product # 14-5698-82) in Immunocytochemistry

Sun Nov 01 00:00:00 EDT 2020

B Cell Activating Factor (BAFF) Is Required for the Development of Intra-Renal Tertiary Lymphoid Organs in Experimental Kidney Transplantation in Rats.

International journal of molecular sciences

Steines L,Poth H,Herrmann M,Schuster A,Banas B,Bergler T

Published figure using Ki-67 monoclonal antibody (Product # 14-5698-82) in Immunohistochemistry

Wed Oct 28 00:00:00 EDT 2020

Lymphoid Aggregates in the CNS of Progressive Multiple Sclerosis Patients Lack Regulatory T Cells.

Frontiers in immunology

Bell L,Lenhart A,Rosenwald A,Monoranu CM,Berberich-Siebelt F

Published figure using Ki-67 monoclonal antibody (Product # 14-5698-82) in Immunohistochemistry

Thu Oct 22 00:00:00 EDT 2020

Pro-myogenic small molecules revealed by a chemical screen on primary muscle stem cells.

Skeletal muscle

Buchanan SM,Price FD,Castiglioni A,Gee AW,Schneider J,Matyas MN,Hayhurst M,Tabebordbar M,Wagers AJ,Rubin LL

14-5698 was used in Immunocytochemistry-immunoflourescence to identify new pathways that can prevent loss of skeletal muscle function or enhance regenerative potential.

Fri Oct 09 00:00:00 EDT 2020

Factors Within the Endoneurial Microenvironment Act to Suppress Tumorigenesis of MPNST.

Frontiers in cellular neuroscience

Stratton JA,Assinck P,Sinha S,Kumar R,Moulson A,Patrick N,Raharjo E,Chan JA,Midha R,Tetzlaff W,Biernaskie J

Published figure using Ki-67 monoclonal antibody (Product # 14-5698-82) in Immunocytochemistry

Thu Oct 01 00:00:00 EDT 2020

Mycobacterium tuberculosis-infected alveolar epithelial cells modulate dendritic cell function through the HIF-1α-NOS2 axis.

Journal of leukocyte biology

Rodrigues TS,Alvarez ARP,Gembre AF,Forni MFPAD,de Melo BMS,Alves Filho JCF,Câmara NOS,Bonato VLD

Published figure using Ki-67 monoclonal antibody (Product # 14-5698-82) in Flow Cytometry

Thu Oct 01 00:00:00 EDT 2020

Genetic Deletion of P2Y₂ Receptor Offers Long-Term (5 Months) Protection Against Lithium-Induced Polyuria, Natriuresis, Kaliuresis, and Collecting Duct Remodeling and Cell Proliferation.

Frontiers in physiology

Zhang Y,Riquier-Brison A,Liu T,Huang Y,Carlson NG,Peti-Peterdi J,Kishore BK

Published figure using Ki-67 monoclonal antibody (Product # 14-5698-82) in Immunofluorescence

Thu Oct 01 00:00:00 EDT 2020

Novel enhanced GFP-positive congenic inbred strain establishment and application of tumor-bearing nude mouse model.

Cancer science

Lan Q,Chen Y,Dai C,Li S,Fei X,Dong J,Shen Y,Dai X,Lu Z,Liu B,Wang Q,Wang H,Zhou Z,Ji X,Wang Z,Huang Q

Published figure using Ki-67 monoclonal antibody (Product # 14-5698-82) in Immunocytochemistry

Thu Oct 01 00:00:00 EDT 2020

Novel enhanced GFP-positive congenic inbred strain establishment and application of tumor-bearing nude mouse model.

Cancer science

Lan Q,Chen Y,Dai C,Li S,Fei X,Dong J,Shen Y,Dai X,Lu Z,Liu B,Wang Q,Wang H,Zhou Z,Ji X,Wang Z,Huang Q

Published figure using Ki-67 monoclonal antibody (Product # 14-5698-82) in Immunocytochemistry

Thu Oct 01 00:00:00 EDT 2020

A Widespread Neurogenic Potential of Neocortical Astrocytes Is Induced by Injury.

Cell stem cell

Zamboni M,Llorens-Bobadilla E,Magnusson JP,Frisén J

14-5698-82 was used in Immunohistochemistry to show that cortical neurogenesis molecularly recapitulates canonical subventricular zone neurogenesis with remarkable fidelity.

Thu Oct 01 00:00:00 EDT 2020

α-Lactosylceramide Protects Against iNKT-Mediated Murine Airway Hyperreactivity and Liver Injury Through Competitive Inhibition of Cd1d Binding.

Frontiers in chemistry

Lai AC,Chi PY,Thio CL,Han YC,Kao HN,Hsieh HW,Gervay-Hague J,Chang YJ

14-5698 was used in Flow cytometry/Cell sorting to study how inhibiting iNKT cell activation with α-Lactosylceramide can reduce development of murine airway hyperreactivity and liver injury by competing for CD1d binding.

Thu Oct 01 00:00:00 EDT 2020

Radiation Induced Metabolic Alterations Associate With Tumor Aggressiveness and Poor Outcome in Glioblastoma.

Frontiers in oncology

Gupta K,Vuckovic I,Zhang S,Xiong Y,Carlson BL,Jacobs J,Olson I,Petterson XM,Macura SI,Sarkaria J,Burns TC

Published figure using Ki-67 monoclonal antibody (Product # 14-5698-82) in Immunocytochemistry

Mon Sep 28 00:00:00 EDT 2020

Radiation Induced Metabolic Alterations Associate With Tumor Aggressiveness and Poor Outcome in Glioblastoma.

Frontiers in oncology

Gupta K,Vuckovic I,Zhang S,Xiong Y,Carlson BL,Jacobs J,Olson I,Petterson XM,Macura SI,Sarkaria J,Burns TC

Published figure using Ki-67 monoclonal antibody (Product # 14-5698-82) in Immunocytochemistry

Mon Sep 28 00:00:00 EDT 2020

Radiation Induced Metabolic Alterations Associate With Tumor Aggressiveness and Poor Outcome in Glioblastoma.

Frontiers in oncology

Gupta K,Vuckovic I,Zhang S,Xiong Y,Carlson BL,Jacobs J,Olson I,Petterson XM,Macura SI,Sarkaria J,Burns TC

Published figure using Ki-67 monoclonal antibody (Product # 14-5698-82) in Immunocytochemistry

Mon Sep 28 00:00:00 EDT 2020

The effects of hedgehog ligand neutralising antibody 5E1 in a mouse model of endometriosis.

BMC research notes

Cousins FL,Farley JK,Kerrigan R,Mukherjee S,Darzi S,Gargett CE,Deane JA

Published figure using Ki-67 monoclonal antibody (Product # 14-5698-82) in Immunocytochemistry

Fri Sep 25 00:00:00 EDT 2020

Egr2-guided histone H2B monoubiquitination is required for peripheral nervous system myelination.

Nucleic acids research

Wüst HM,Wegener A,Fröb F,Hartwig AC,Wegwitz F,Kari V,Schimmel M,Tamm ER,Johnsen SA,Wegner M,Sock E

Published figure using Ki-67 monoclonal antibody (Product # 14-5698-82) in Immunocytochemistry

Fri Sep 18 00:00:00 EDT 2020

Egr2-guided histone H2B monoubiquitination is required for peripheral nervous system myelination.

Nucleic acids research

Wüst HM,Wegener A,Fröb F,Hartwig AC,Wegwitz F,Kari V,Schimmel M,Tamm ER,Johnsen SA,Wegner M,Sock E

Published figure using Ki-67 monoclonal antibody (Product # 14-5698-82) in Immunocytochemistry

Fri Sep 18 00:00:00 EDT 2020

Macrophage migration inhibitory factor inhibition as a novel therapeutic approach against triple-negative breast cancer.

Cell death & disease

Charan M,Das S,Mishra S,Chatterjee N,Varikuti S,Kaul K,Misri S,Ahirwar DK,Satoskar AR,Ganju RK

14-5698 was used in Immunohistochemistry to study the role of Macrophage migration inhibitory factor (MIF) in Triple-negative breast cancer (TNBC) progression and metastasis.

Thu Sep 17 00:00:00 EDT 2020

Signalling codes for the maintenance and lineage commitment of embryonic gastric epithelial progenitors.

Development (Cambridge, England)

Sayols S,Klassek J,Werner C,Möckel S,Ritz S,Mendez-Lago M,Soshnikova N

14-5698 was used in Immunohistochemistry to assess whether Axin2- and Lgr5-expressing cells are gastric progenitors in the developing mouse stomach.

Tue Sep 15 00:00:00 EDT 2020

Inducible IL-7 Hyperexpression Influences Lymphocyte Homeostasis and Function and Increases Allograft Rejection.

Frontiers in immunology

Schreiber M,Weigelt M,Karasinsky A,Anastassiadis K,Schallenberg S,Petzold C,Bonifacio E,Kretschmer K,Hommel A

14-5698 was used in Flow cytometry/Cell sorting to show that transient hyperexpression of IL-7 can impair immune regulation, through disturbances in lymphocyte development pathways, and decrease graft survival time, even under immunosuppression.

Mon Sep 14 00:00:00 EDT 2020

Regulation of stem/progenitor cell maintenance by BMP5 in prostate homeostasis and cancer initiation.

eLife

Tremblay M,Viala S,Shafer ME,Graham-Paquin AL,Liu C,Bouchard M

14-5698 was used in Immunohistochemistry-immunofluorescence to explore the regulation of stem / progenitor cell homeostasis by BMP5.

Mon Sep 07 00:00:00 EDT 2020

Inflammatory Signals Induce AT2 Cell-Derived Damage-Associated Transient Progenitors that Mediate Alveolar Regeneration.

Cell stem cell

Choi J,Park JE,Tsagkogeorga G,Yanagita M,Koo BK,Han N,Lee JH

14-5698-82 was used in Immunohistochemistry (Paraffin) to map the trajectories of alveolar-lineage cells during injury repair and lung regeneration by single-cell RNA sequencing in combination with in vivo lineage tracing and organoid models.

Thu Sep 03 00:00:00 EDT 2020

DSCAM regulates delamination of neurons in the developing midbrain.

Science advances

Arimura N,Okada M,Taya S,Dewa KI,Tsuzuki A,Uetake H,Miyashita S,Hashizume K,Shimaoka K,Egusa S,Nishioka T,Yanagawa Y,Yamakawa K,Inoue YU,Inoue T,Kaibuchi K,Hoshino M

14-5698 was used in Immunohistochemistry to show that Down syndrome cell adhesion molecule (DSCAM) controls neuronal delamination by local suppression of the RapGEF2-Rap1-N-cadherin cascade at the apical endfeet in the dorsal midbrain.

Tue Sep 01 00:00:00 EDT 2020

Regulatory T-cells regulate neonatal heart regeneration by potentiating cardiomyocyte proliferation in a paracrine manner.

Theranostics

Li J,Yang KY,Tam RCY,Chan VW,Lan HY,Hori S,Zhou B,Lui KO

Published figure using Ki-67 monoclonal antibody (Product # 14-5698-82) in Immunocytochemistry

Fri Aug 14 00:00:00 EDT 2020

Deletion of Calcineurin in Schwann Cells Does Not Affect Developmental Myelination, But Reduces Autophagy and Delays Myelin Clearance after Peripheral Nerve Injury.

The Journal of neuroscience : the official journal of the Society for Neuroscience

Reed CB,Frick LR,Weaver A,Sidoli M,Schlant E,Feltri ML,Wrabetz L

14-5698-82 was used in Immunohistochemistry (Frozen) to assess the effects of CnB ablation on peripheral myelination after birth in both male and female mice.

Wed Aug 05 00:00:00 EDT 2020

NPC1 deficiency impairs cerebellar postnatal development of microglia and climbing fiber refinement in a mouse model of Niemann-Pick disease type C.

Development (Cambridge, England)

Boyle BR,Melli SE,Altreche RS,Padron ZM,Yousufzai FAK,Kim S,Vasquez MD,Carone DM,Carone BR,Soto I

14-5698 was used in Immunohistochemistry to analyse the effect of NPC1 deficiency on microglia and on climbing fiber synaptic refinement during cerebellar postnatal development using the Npc1nmf164 mouse.

Mon Aug 03 00:00:00 EDT 2020

Combining In Vivo and Organotypic In Vitro Approaches to Assess the Human Relevance of Basimglurant (RG7090), a Potential CAR Activator.

Toxicological sciences : an official journal of the Society of Toxicology

Nudischer R,Renggli K,Bertinetti-Lapatki C,Hoflack JC,Flint N,Sewing S,Pedersen L,Schadt S,Higgins LG,Vardy A,Lenz B,Gand L,Boess F,Elcombe BM,Hierlemann A,Roth AB

14-5698 was used in Immunohistochemistry to suggest RG7090 to be a rodent-specific CAR activator, and that CAR activation and its downstream processes were involved in the foci of altered hepatocytes formation detected in vivo.

Sat Aug 01 00:00:00 EDT 2020

Comparing the fate of brain metastatic breast cancer cells in different immune compromised mice with cellular magnetic resonance imaging.

Clinical & experimental metastasis

Knier NN,Hamilton AM,Foster PJ

14-5698-82 was used in Immunohistochemistry to track the fate of a mammary carcinoma cell line (MDA-MB-231-BR) in vivo to characterize the growth of brain metastases in the nude and severely immune-compromised NOD/SCID/ILIIrg-/- (NSG) mouse.

Sat Aug 01 00:00:00 EDT 2020

FGF2 modulates simultaneously the mode, the rate of division and the growth fraction in cultures of radial glia.

Development (Cambridge, England)

Ledesma-Terrón M,Peralta-Cañadas N,Míguez DG

Published figure using Ki-67 monoclonal antibody (Product # 14-5698-82) in Immunocytochemistry

Fri Jul 24 00:00:00 EDT 2020

FGF2 modulates simultaneously the mode, the rate of division and the growth fraction in cultures of radial glia.

Development (Cambridge, England)

Ledesma-Terrón M,Peralta-Cañadas N,Míguez DG

Published figure using Ki-67 monoclonal antibody (Product # 14-5698-82) in Immunocytochemistry

Fri Jul 24 00:00:00 EDT 2020

Blocking Notch-Signaling Increases Neurogenesis in the Striatum after Stroke.

Cells

Santopolo G,Magnusson JP,Lindvall O,Kokaia Z,Frisén J

14-5698-82 was used in Immunocytochemistry to suggest inhibition of Notch-signaling as a potential translational strategy to promote neuronal regeneration after stroke.

Mon Jul 20 00:00:00 EDT 2020

Treatment of mice with a ligand binding blocking anti-CD28 monoclonal antibody improves healing after myocardial infarction.

PloS one

Gladow N,Hollmann C,Ramos G,Frantz S,Kerkau T,Beyersdorf N,Hofmann U

Published figure using Ki-67 monoclonal antibody (Product # 14-5698-82) in Flow Cytometry

Mon Jul 06 00:00:00 EDT 2020

Microbiota-Sourced Purines Support Wound Healing and Mucous Barrier Function.

iScience

Lee JS,Wang RX,Goldberg MS,Clifford GP,Kao DJ,Colgan SP

14-5698-82 was used in Immunohistochemistry (Paraffin) to reveal the gut microbiota as a prominent source of exogenous purines and that such microbiota-sourced purines (MSPs) are available to the intestinal mucosa.

Fri Jun 26 00:00:00 EDT 2020

A single-cell transcriptomic and anatomic atlas of mouse dorsal raphe Pet1 neurons.

eLife

Okaty BW,Sturrock N,Escobedo Lozoya Y,Chang Y,Senft RA,Lyon KA,Alekseyenko OV,Dymecki SM

Published figure using Ki-67 monoclonal antibody (Product # 14-5698-82) in Immunohistochemistry

Mon Jun 22 00:00:00 EDT 2020

A single-cell transcriptomic and anatomic atlas of mouse dorsal raphe Pet1 neurons.

eLife

Okaty BW,Sturrock N,Escobedo Lozoya Y,Chang Y,Senft RA,Lyon KA,Alekseyenko OV,Dymecki SM

Published figure using Ki-67 monoclonal antibody (Product # 14-5698-82) in Immunohistochemistry

Mon Jun 22 00:00:00 EDT 2020

Multidimensional hydrogel models reveal endothelial network angiocrine signals increase glioblastoma cell number, invasion, and temozolomide resistance.

Integrative biology : quantitative biosciences from nano to macro

Ngo MT,Karvelis E,Harley BAC

14-5698 was used in Immunocytochemistry-immunoflourescence to highlight the use of multidimensional hydrogel models to evaluate the role of angiocrine signals in glioblastoma progression.

Fri Jun 19 00:00:00 EDT 2020

Comparative Analysis of Age-Related Changes in Lacrimal Glands and Meibomian Glands of a C57BL/6 Male Mouse Model.

International journal of molecular sciences

Yoon CH,Ryu JS,Hwang HS,Kim MK

Published figure using Ki-67 monoclonal antibody (Product # 14-5698-82) in Immunohistochemistry

Thu Jun 11 00:00:00 EDT 2020

Comparative Analysis of Age-Related Changes in Lacrimal Glands and Meibomian Glands of a C57BL/6 Male Mouse Model.

International journal of molecular sciences

Yoon CH,Ryu JS,Hwang HS,Kim MK

Published figure using Ki-67 monoclonal antibody (Product # 14-5698-82) in Immunohistochemistry

Thu Jun 11 00:00:00 EDT 2020

Transcriptome analysis of basic fibroblast growth factor treated stem cells isolated from human exfoliated deciduous teeth.

Heliyon

Nowwarote N,Manokawinchoke J,Kanjana K,Fournier BPJ,Sukarawan W,Osathanon T

Published figure using Ki-67 monoclonal antibody (Product # 14-5698-82) in Immunocytochemistry

Mon Jun 01 00:00:00 EDT 2020

Transcriptome analysis of basic fibroblast growth factor treated stem cells isolated from human exfoliated deciduous teeth.

Heliyon

Nowwarote N,Manokawinchoke J,Kanjana K,Fournier BPJ,Sukarawan W,Osathanon T

Published figure using Ki-67 monoclonal antibody (Product # 14-5698-82) in Immunocytochemistry

Mon Jun 01 00:00:00 EDT 2020

Genetic manipulation of LKB1 elicits lethal metastatic prostate cancer.

The Journal of experimental medicine

Hermanova I,Zúñiga-García P,Caro-Maldonado A,Fernandez-Ruiz S,Salvador F,Martín-Martín N,Zabala-Letona A,Nuñez-Olle M,Torrano V,Camacho L,Lizcano JM,Talamillo A,Carreira S,Gurel B,Cortazar AR,Guiu M,López JI,Martinez-Romero A,Astobiza I,Valcarcel-Jimenez L,Lorente M,Arruabarrena-Aristorena A,Velasco G,Gomez-Muñoz A,Suárez-Cabrera C,Lodewijk I,Flores JM,Sutherland JD,Barrio R,de Bono JS,Paramio JM,Trka J,Graupera M,Gomis RR,Carracedo A

Published figure using Ki-67 monoclonal antibody (Product # 14-5698-82) in Immunohistochemistry

Mon Jun 01 00:00:00 EDT 2020

Genetic manipulation of LKB1 elicits lethal metastatic prostate cancer.

The Journal of experimental medicine

Published figure using Ki-67 monoclonal antibody (Product # 14-5698-82) in Immunohistochemistry

Mon Jun 01 00:00:00 EDT 2020

Myofibroblast contraction is essential for generating and regenerating the gas-exchange surface.

The Journal of clinical investigation

Li R,Li X,Hagood J,Zhu MS,Sun X

14-5698 was used in Immunohistochemistry to show that inactivation of myosin light chain kinase (MLCK), a key factor required for myofibroblast contraction, disrupted septa formation, supporting the myofibroblast contraction model of alveologenesis.

Mon Jun 01 00:00:00 EDT 2020

Renewal and Differentiation of GCD Necklace Olfactory Sensory Neurons.

Chemical senses

Bloom ML,Johnston LB,Datta SR

14-5698-82 was used in Immunohistochemistry to demonstrate that-like their canonical counterparts-GCD OSNs undergo continuous renewal and define a GCD-specific developmental trajectory linking neurogenesis, maturation, and migration.

Fri May 29 00:00:00 EDT 2020

Discrete populations of isotype-switched memory B lymphocytes are maintained in murine spleen and bone marrow.

Nature communications

Riedel R,Addo R,Ferreira-Gomes M,Heinz GA,Heinrich F,Kummer J,Greiff V,Schulz D,Klaeden C,Cornelis R,Menzel U,Kröger S,Stervbo U,Köhler R,Haftmann C,Kühnel S,Lehmann K,Maschmeyer P,McGrath M,Naundorf S,Hahne S,Sercan-Alp Ö,Siracusa F,Stefanowski J,Weber M,Westendorf K,Zimmermann J,Hauser AE,Reddy ST,Durek P,Chang HD,Mashreghi MF,Radbruch A

Published figure using Ki-67 monoclonal antibody (Product # 14-5698-82) in Flow Cytometry

Fri May 22 00:00:00 EDT 2020

Agrin Promotes Limbal Stem Cell Proliferation and Corneal Wound Healing Through Hippo-Yap Signaling Pathway.

Investigative ophthalmology & visual science

Hou L,Fu W,Liu Y,Wang Q,Wang L,Huang Y

14-5698 was used in Immunocytochemistry to show how agrin promotes the proliferation of limbal stem cells and accelerates the healing rate of cornceal would through Hippo-Yap signalling pathway.

Mon May 11 00:00:00 EDT 2020

The neuroregenerative effects of topical decorin on the injured mouse cornea.

Journal of neuroinflammation

Wu M,Downie LE,Grover LM,Moakes RJA,Rauz S,Logan A,Jiao H,Hill LJ,Chinnery HR

14-5698 was used in Immunohistochemistry-wholemount to support a role for decorin in DC-mediated neuroregeneration following corneal abrasion injury.

Mon May 04 00:00:00 EDT 2020

Creation of Laryngeal Grafts from Primary Human Cells and Decellularized Laryngeal Scaffolds.

Tissue engineering. Part A

Moser PT,Gerli M,Diercks GR,Evangelista-Leite D,Charest JM,Gershlak JR,Ren X,Gilpin SE,Jank BJ,Gaudette GR,Hartnick CJ,Ott HC

14-5698 was used in Immunohistochemistry to report the de novo formation of three humanized laryngeal tissue compartments under one uniform culture condition, a possible keystone in creating vital composite tissue grafts for laryngeal regeneration.

Fri May 01 00:00:00 EDT 2020

New Insights into the Pathogenesis of Diabetic Nephropathy: Proximal Renal Tubules Are Primary Target of Oxidative Stress in Diabetic Kidney.

Acta histochemica et cytochemica

Haraguchi R,Kohara Y,Matsubayashi K,Kitazawa R,Kitazawa S

14-5698 was used in Immunohistochemistry-immunofluorescence to study new mechanisms involved in the pathogenesis of diabetic nephropathy.

Tue Apr 28 00:00:00 EDT 2020

A discrete subtype of neural progenitor crucial for cortical folding in the gyrencephalic mammalian brain.

eLife

Matsumoto N,Tanaka S,Horiike T,Shinmyo Y,Kawasaki H

Published figure using Ki-67 monoclonal antibody (Product # 14-5698-82) in Immunocytochemistry

Tue Apr 21 00:00:00 EDT 2020

A discrete subtype of neural progenitor crucial for cortical folding in the gyrencephalic mammalian brain.

eLife

Matsumoto N,Tanaka S,Horiike T,Shinmyo Y,Kawasaki H

Published figure using Ki-67 monoclonal antibody (Product # 14-5698-82) in Immunocytochemistry

Tue Apr 21 00:00:00 EDT 2020

A discrete subtype of neural progenitor crucial for cortical folding in the gyrencephalic mammalian brain.

eLife

Matsumoto N,Tanaka S,Horiike T,Shinmyo Y,Kawasaki H

Published figure using Ki-67 monoclonal antibody (Product # 14-5698-82) in Immunocytochemistry

Tue Apr 21 00:00:00 EDT 2020

Yolk-sac-derived macrophages progressively expand in the mouse kidney with age.

eLife

Ide S,Yahara Y,Kobayashi Y,Strausser SA,Ide K,Watwe A,Xu-Vanpala S,Privratsky JR,Crowley SD,Shinohara ML,Alman BA,Souma T

14-5698 was used in Immunocytochemistry-immunoflourescence to find that yolk-sac-derived macrophages progressively expand in number with age and become a major contributor to the renal macrophage population in older mice.

Fri Apr 17 00:00:00 EDT 2020

Eradication of tumor growth by delivering novel photothermal selenium-coated tellurium nanoheterojunctions.

Science advances

Chen S,Xing C,Huang D,Zhou C,Ding B,Guo Z,Peng Z,Wang D,Zhu X,Liu S,Cai Z,Wu J,Zhao J,Wu Z,Zhang Y,Wei C,Yan Q,Wang H,Fan D,Liu L,Zhang H,Cao Y

14-5698 was used in Immunohistochemistry-immunofluorescence to develop and characterise a novel anti-cancer therapy using nanomaterial-based photothermal therapy (PTT).

Wed Apr 01 00:00:00 EDT 2020

Metastasis-initiating cells induce and exploit a fibroblast niche to fuel malignant colonization of the lungs.

Nature communications

Pein M,Insua-Rodríguez J,Hongu T,Riedel A,Meier J,Wiedmann L,Decker K,Essers MAG,Sinn HP,Spaich S,Sütterlin M,Schneeweiss A,Trumpp A,Oskarsson T

Published figure using Ki-67 monoclonal antibody (Product # 14-5698-82) in Immunohistochemistry

Fri Mar 20 00:00:00 EDT 2020

Oxidative stress regulates progenitor behavior and cortical neurogenesis.

Development (Cambridge, England)

Chui A,Zhang Q,Dai Q,Shi SH

14-5698 was used in Immunohistochemistry to suggest that oxidative stress actively regulates RGP behavior to ensure proper neurogenesis in the mammalian cortex.

Wed Mar 11 00:00:00 EDT 2020

Epithelial Vegfa Specifies a Distinct Endothelial Population in the Mouse Lung.

Developmental cell

Vila Ellis L,Cain MP,Hutchison V,Flodby P,Crandall ED,Borok Z,Zhou B,Ostrin EJ,Wythe JD,Chen J

Published figure using Ki-67 monoclonal antibody (Product # 14-5698-82) in Immunocytochemistry

Mon Mar 09 00:00:00 EDT 2020

GPRC5A facilitates cell proliferation through cell cycle regulation and correlates with bone metastasis in prostate cancer.

International journal of cancer

Sawada Y,Kikugawa T,Iio H,Sakakibara I,Yoshida S,Ikedo A,Yanagihara Y,Saeki N,Győrffy B,Kishida T,Okubo Y,Nakamura Y,Miyagi Y,Saika T,Imai Y

14-5698-82 was used in Immunohistochemistry (Paraffin) to to investigate if GPRC5A can be a possible therapeutic target and prognostic marker molecule for progressive prostate cancer.

Sun Mar 01 00:00:00 EST 2020

Histone Methylations Define Neural Stem/Progenitor Cell Subtypes in the Mouse Subventricular Zone.

Molecular neurobiology

Zhang Z,Manaf A,Li Y,Perez SP,Suganthan R,Dahl JA,Bjørås M,Klungland A

14-5698 was used in Immunocytochemistry-immunoflourescence to define different subtypes of neural stem/progenitor cells (NSPCs) by individual histone methylations.

Sat Feb 01 00:00:00 EST 2020

NiCHE Platform: Nature-Inspired Catechol-Conjugated Hyaluronic Acid Environment Platform for Salivary Gland Tissue Engineering.

ACS applied materials & interfaces

Lee SW,Ryu JH,Do MJ,Namkoong E,Lee H,Park K

14-5698-82 was used in Immunocytochemistry to model an optimum artificial microenvironment to allow for salivary gland tissue engineering.

Wed Jan 29 00:00:00 EST 2020

Follicular Regulatory T Cells Can Access the Germinal Center Independently of CXCR5.

Cell reports

Vanderleyden I,Fra-Bido SC,Innocentin S,Stebegg M,Okkenhaug H,Evans-Bailey N,Pierson W,Denton AE,Linterman MA

Published figure using Ki-67 monoclonal antibody (Product # 14-5698-82) in Immunofluorescence

Tue Jan 21 00:00:00 EST 2020

Follicular Regulatory T Cells Can Access the Germinal Center Independently of CXCR5.

Cell reports

Vanderleyden I,Fra-Bido SC,Innocentin S,Stebegg M,Okkenhaug H,Evans-Bailey N,Pierson W,Denton AE,Linterman MA

Published figure using Ki-67 monoclonal antibody (Product # 14-5698-82) in Immunofluorescence

Tue Jan 21 00:00:00 EST 2020

Interleukin-13 disrupts type 2 pneumocyte stem cell activity.

JCI insight

Glisinski KM,Schlobohm AJ,Paramore SV,Birukova A,Moseley MA,Foster MW,Barkauskas CE

Published figure using Ki-67 monoclonal antibody (Product # 14-5698-82) in Immunohistochemistry

Thu Jan 16 00:00:00 EST 2020

Interleukin-13 disrupts type 2 pneumocyte stem cell activity.

JCI insight

Glisinski KM,Schlobohm AJ,Paramore SV,Birukova A,Moseley MA,Foster MW,Barkauskas CE

Published figure using Ki-67 monoclonal antibody (Product # 14-5698-82) in Immunohistochemistry

Thu Jan 16 00:00:00 EST 2020

Chemosensitization of prostate cancer stem cells in mice by angiogenin and plexin-B2 inhibitors.

Communications biology

Li S,Goncalves KA,Lyu B,Yuan L,Hu GF

Published figure using Ki-67 monoclonal antibody (Product # 14-5698-82) in Flow Cytometry

Wed Jan 15 00:00:00 EST 2020

Progressive Pulmonary Fibrosis Is Caused by Elevated Mechanical Tension on Alveolar Stem Cells.

Cell

Wu H,Yu Y,Huang H,Hu Y,Fu S,Wang Z,Shi M,Zhao X,Yuan J,Li J,Yang X,Bin E,Wei D,Zhang H,Zhang J,Yang C,Cai T,Dai H,Chen J,Tang N

14-5698-82 was used in Immunohistochemistry (PFA fixed) to discover that loss of Cdc42 function in alveolar stem cells (AT2 cells) causes periphery-to-center progressive lung fibrosis.

Thu Jan 09 00:00:00 EST 2020

Myelin-specific CD8+ T cells exacerbate brain inflammation in CNS autoimmunity.

The Journal of clinical investigation

Wagner CA,Roqué PJ,Mileur TR,Liggitt D,Goverman JM

14-5698-82 was used in Flow Cytometry to suggest that myelin-specific CD8+ T cells may contribute to disease pathogenesis via a FasL-dependent mechanism that preferentially promotes lesion formation in the brain.

Thu Jan 02 00:00:00 EST 2020

In Vivo Lineage Tracing of Polyploid Hepatocytes Reveals Extensive Proliferation during Liver Regeneration.

Cell stem cell

Matsumoto T,Wakefield L,Tarlow BD,Grompe M

14-5698 was used in Immunocytochemistry-immunoflourescence to study the regenerative capacity of polyploid hepatocytes during liver regeneration.

Thu Jan 02 00:00:00 EST 2020

Quinazolinone derivative BNUA-3 ameliorated [NDEA+2-AAF]-induced liver carcinogenesis in SD rats by modulating AhR-CYP1B1-Nrf2-Keap1 pathway.

Clinical and experimental pharmacology & physiology

Bose P,Siddique MUM,Acharya R,Jayaprakash V,Sinha BN,Lapenna A,Pattanayak SP

Published figure using Ki-67 monoclonal antibody (Product # 14-5698-82) in Immunohistochemistry

Wed Jan 01 00:00:00 EST 2020

JAK-STAT inhibition impairs K-RAS-driven lung adenocarcinoma progression.

International journal of cancer

Mohrherr J,Haber M,Breitenecker K,Aigner P,Moritsch S,Voronin V,Eferl R,Moriggl R,Stoiber D,Győrffy B,Brcic L,László V,Döme B,Moldvay J,Dezső K,Bilban M,Popper H,Moll HP,Casanova E

Published figure using Ki-67 monoclonal antibody (Product # 14-5698-82) in Immunohistochemistry

Sun Dec 15 00:00:00 EST 2019

1810011o10 Rik Inhibits the Antitumor Effect of Intratumoral CD8⁺ T Cells through Suppression of Notch2 Pathway in a Murine Hepatocellular Carcinoma Model.

Frontiers in immunology

Dai K,Huang L,Huang YB,Chen ZB,Yang LH,Jiang YA

Published figure using Ki-67 monoclonal antibody (Product # 14-5698-82) in Flow Cytometry

Wed Nov 20 00:00:00 EST 2019

Diabetes-Induced NF-κB Dysregulation in Skeletal Stem Cells Prevents Resolution of Inflammation.

Diabetes

Ko KI,Syverson AL,Kralik RM,Choi J,DerGarabedian BP,Chen C,Graves DT

14-5698-82 was used in Immunohistochemistry to demonstrate that type 1 diabetes induces NF-κB hyperactivation in skeletal stem cells to disrupt their ability to modulate M2 polarisation and resolve inflammation.

Fri Nov 01 00:00:00 EDT 2019

Transcriptional Signature Derived from Murine Tumor-Associated Macrophages Correlates with Poor Outcome in Breast Cancer Patients.

Cell reports

Tuit S,Salvagno C,Kapellos TS,Hau CS,Seep L,Oestreich M,Klee K,de Visser KE,Ulas T,Schultze JL

14-5698 was used in Immunocytochemistry-immunoflourescence to show that a transgenic mouse tumor model can yield a TAM signature relevant for human breast cancer outcome prognosis and provide a generalizable strategy for determining and applying immune cell signatures provided the murine model reflects the human disease.

Tue Oct 29 00:00:00 EDT 2019

ATF3 Sustains IL-22-Induced STAT3 Phosphorylation to Maintain Mucosal Immunity Through Inhibiting Phosphatases.

Frontiers in immunology

Glal D,Sudhakar JN,Lu HH,Liu MC,Chiang HY,Liu YC,Cheng CF,Shui JW

Published figure using Ki-67 monoclonal antibody (Product # 14-5698-82) in Flow Cytometry

Thu Sep 26 00:00:00 EDT 2019

Sensing of apoptotic cells through Axl causes lung basal cell proliferation in inflammatory diseases.

The Journal of experimental medicine

Fujino N,Brand OJ,Morgan DJ,Fujimori T,Grabiec AM,Jagger CP,Maciewicz RA,Yamada M,Itakura K,Sugiura H,Ichinose M,Hussell T

Published figure using Ki-67 monoclonal antibody (Product # 14-5698-82) in Immunofluorescence

Mon Sep 02 00:00:00 EDT 2019

Sensing of apoptotic cells through Axl causes lung basal cell proliferation in inflammatory diseases.

The Journal of experimental medicine

Fujino N,Brand OJ,Morgan DJ,Fujimori T,Grabiec AM,Jagger CP,Maciewicz RA,Yamada M,Itakura K,Sugiura H,Ichinose M,Hussell T

Published figure using Ki-67 monoclonal antibody (Product # 14-5698-82) in Immunofluorescence

Mon Sep 02 00:00:00 EDT 2019

Sensing of apoptotic cells through Axl causes lung basal cell proliferation in inflammatory diseases.

The Journal of experimental medicine

Fujino N,Brand OJ,Morgan DJ,Fujimori T,Grabiec AM,Jagger CP,Maciewicz RA,Yamada M,Itakura K,Sugiura H,Ichinose M,Hussell T

Published figure using Ki-67 monoclonal antibody (Product # 14-5698-82) in Immunofluorescence

Mon Sep 02 00:00:00 EDT 2019

Analysis of biological networks in the endothelium with biomimetic microsystem platform.

American journal of physiology. Lung cellular and molecular physiology

Kruse K,Klomp J,Sun M,Chen Z,Santana D,Huang F,Kanabar P,Maienschein-Cline M,Komarova YA

14-5698-82 was used in Immunocytochemistry to describe a novel method for studying the protein "interactome" in primary human cells and apply this method to investigate the effect of posttranslational protein modifications (PTMs) on the protein''s functions.

Sun Sep 01 00:00:00 EDT 2019

An autocrine ActivinB mechanism drives TGFβ/Activin signaling in Group 3 medulloblastoma.

EMBO molecular medicine

Morabito M,Larcher M,Cavalli FM,Foray C,Forget A,Mirabal-Ortega L,Andrianteranagna M,Druillennec S,Garancher A,Masliah-Planchon J,Leboucher S,Debalkew A,Raso A,Delattre O,Puget S,Doz F,Taylor MD,Ayrault O,Bourdeaut F,Eychène A,Pouponnot C

14-5698-82 was used in Immunohistochemistry to demonstrate that an ActivinB autocrine stimulation is responsible for pathway activation in a subset of Group 3 MB characterized by high PMEPA1 levels.

Thu Aug 01 00:00:00 EDT 2019

Evidence of a developmental origin for β-cell heterogeneity using a dual lineage-tracing technology.

Development (Cambridge, England)

Chen C,Shiota C,Agostinelli G,Ridley D,Jiang Y,Ma J,Prasadan K,Xiao X,Gittes GK

14-5698 was used in Immunohistochemistry to develop a dual lineage-tracing technology, using a combination of two recombinase systems, Dre/RoxP and Cre/LoxP, to independently trace green fluorescent Pdx1-lineage cells and red fluorescent Ptf1a-lineage cells in the developing and adult mouse pancreas.

Thu Jun 27 00:00:00 EDT 2019

Targeted Delivery of Stk25 Antisense Oligonucleotides to Hepatocytes Protects Mice Against Nonalcoholic Fatty Liver Disease.

Cellular and molecular gastroenterology and hepatology

Cansby E,Nuñez-Durán E,Magnusson E,Amrutkar M,Booten SL,Kulkarni NM,Svensson LT,Borén J,Marschall HU,Aghajan M,Mahlapuu M

Published figure using Ki-67 monoclonal antibody (Product # 14-5698-82) in Immunohistochemistry

Tue Jun 04 00:00:00 EDT 2019

Lymphangiogenesis in kidney and lymph node mediates renal inflammation and fibrosis.

Science advances

Pei G,Yao Y,Yang Q,Wang M,Wang Y,Wu J,Wang P,Li Y,Zhu F,Yang J,Zhang Y,Yang W,Deng X,Zhao Z,Zhu H,Ge S,Han M,Zeng R,Xu G

14-5698 was used in Flow cytometry/Cell sorting to demonstrate that expanding lymphatic vessels (LVs) in kidneys and corresponding renal draining lymph nodes (RDLNs) play critical roles in promoting intrarenal inflammation and fibrosis following renal injury.

Sat Jun 01 00:00:00 EDT 2019

SORLA regulates endosomal trafficking and oncogenic fitness of HER2.

Nature communications

Pietilä M,Sahgal P,Peuhu E,Jäntti NZ,Paatero I,Närvä E,Al-Akhrass H,Lilja J,Georgiadou M,Andersen OM,Padzik A,Sihto H,Joensuu H,Blomqvist M,Saarinen I,Boström PJ,Taimen P,Ivaska J

Published figure using Ki-67 monoclonal antibody (Product # 14-5698-82) in Immunohistochemistry

Tue May 28 00:00:00 EDT 2019

Deficiency in the secreted protein Semaphorin3d causes abnormal parathyroid development in mice.

The Journal of biological chemistry

Singh A,Mia MM,Cibi DM,Arya AK,Bhadada SK,Singh MK

Published figure using Ki-67 monoclonal antibody (Product # 14-5698-82) in Immunocytochemistry

Fri May 24 00:00:00 EDT 2019

Deficiency in the secreted protein Semaphorin3d causes abnormal parathyroid development in mice.

The Journal of biological chemistry

Singh A,Mia MM,Cibi DM,Arya AK,Bhadada SK,Singh MK

Published figure using Ki-67 monoclonal antibody (Product # 14-5698-82) in Immunocytochemistry

Fri May 24 00:00:00 EDT 2019

High-Molecular-Weight Hyaluronan Is a Hippo Pathway Ligand Directing Cell Density-Dependent Growth Inhibition via PAR1b.

Developmental cell

Ooki T,Murata-Kamiya N,Takahashi-Kanemitsu A,Wu W,Hatakeyama M

14-5698 was used in Immunocytochemistry-immunoflourescence to show that treatment with high-molecular-weight hyaluronan stimulates tumor-suppressive Hippo signaling in breast epithelial cells.

Mon May 20 00:00:00 EDT 2019

Krt5⁺/Krt15⁺ foregut basal progenitors give rise to cyclooxygenase-2-dependent tumours in response to gastric acid stress.

Nature communications

Moon H,Zhu J,Donahue LR,Choi E,White AC

14-5698 was used in Immunohistochemistry-immunofluorescence to suggest that clinical management of microenvironmental stressor-mediated microscopic injury may be important in delaying tumor initiation from foregut basal progenitor cells expressing pre-existing tumorigenic mutation(s) and genetic alteration(s).

Mon May 20 00:00:00 EDT 2019

FCRL5⁺ Memory B Cells Exhibit Robust Recall Responses.

Cell reports

Kim CC,Baccarella AM,Bayat A,Pepper M,Fontana MF

Published figure using Ki-67 monoclonal antibody (Product # 14-5698-82) in Flow Cytometry

Tue Apr 30 00:00:00 EDT 2019

Pulsatile MEK Inhibition Improves Anti-tumor Immunity and T Cell Function in Murine Kras Mutant Lung Cancer.

Cell reports

Choi H,Deng J,Li S,Silk T,Dong L,Brea EJ,Houghton S,Redmond D,Zhong H,Boiarsky J,Akbay EA,Smith PD,Merghoub T,Wong KK,Wolchok JD

Published figure using Ki-67 monoclonal antibody (Product # 14-5698-82) in Flow Cytometry

Tue Apr 16 00:00:00 EDT 2019

Anti-commensal IgG Drives Intestinal Inflammation and Type 17 Immunity in Ulcerative Colitis.

Immunity

Castro-Dopico T,Dennison TW,Ferdinand JR,Mathews RJ,Fleming A,Clift D,Stewart BJ,Jing C,Strongili K,Labzin LI,Monk EJM,Saeb-Parsy K,Bryant CE,Clare S,Parkes M,Clatworthy MR

Published figure using Ki-67 monoclonal antibody (Product # 14-5698-82) in Immunofluorescence

Tue Apr 16 00:00:00 EDT 2019

Anti-commensal IgG Drives Intestinal Inflammation and Type 17 Immunity in Ulcerative Colitis.

Immunity

Castro-Dopico T,Dennison TW,Ferdinand JR,Mathews RJ,Fleming A,Clift D,Stewart BJ,Jing C,Strongili K,Labzin LI,Monk EJM,Saeb-Parsy K,Bryant CE,Clare S,Parkes M,Clatworthy MR

Published figure using Ki-67 monoclonal antibody (Product # 14-5698-82) in Immunofluorescence

Tue Apr 16 00:00:00 EDT 2019

Origin and differentiation trajectories of fibroblastic reticular cells in the splenic white pulp.

Nature communications

Cheng HW,Onder L,Novkovic M,Soneson C,Lütge M,Pikor N,Scandella E,Robinson MD,Miyazaki JI,Tersteegen A,Sorg U,Pfeffer K,Rülicke T,Hehlgans T,Ludewig B

Published figure using Ki-67 monoclonal antibody (Product # 14-5698-82) in Immunohistochemistry

Mon Apr 15 00:00:00 EDT 2019

Distinct response of adult neural stem cells to low versus high dose ionising radiation.

DNA repair

Barazzuol L,Hopkins SR,Ju L,Jeggo PA

14-5698-82 was used in Immunohistochemistry to examine the response of stem and progenitor cells in the subventricular zone to low IR doses (50-500 mGy).

Mon Apr 01 00:00:00 EDT 2019

Soluble TREM2 ameliorates pathological phenotypes by modulating microglial functions in an Alzheimer's disease model.

Nature communications

Zhong L,Xu Y,Zhuo R,Wang T,Wang K,Huang R,Wang D,Gao Y,Zhu Y,Sheng X,Chen K,Wang N,Zhu L,Can D,Marten Y,Shinohara M,Liu CC,Du D,Sun H,Wen L,Xu H,Bu G,Chen XF

Published figure using Ki-67 monoclonal antibody (Product # 14-5698-82) in Immunohistochemistry

Mon Mar 25 00:00:00 EDT 2019

Live imaging of alveologenesis in precision-cut lung slices reveals dynamic epithelial cell behaviour.

Nature communications

Akram KM,Yates LL,Mongey R,Rothery S,Gaboriau DCA,Sanderson J,Hind M,Griffiths M,Dean CH

Published figure using Ki-67 monoclonal antibody (Product # 14-5698-82) in Immunofluorescence

Tue Mar 12 00:00:00 EDT 2019

Live imaging of alveologenesis in precision-cut lung slices reveals dynamic epithelial cell behaviour.

Nature communications

Akram KM,Yates LL,Mongey R,Rothery S,Gaboriau DCA,Sanderson J,Hind M,Griffiths M,Dean CH

Published figure using Ki-67 monoclonal antibody (Product # 14-5698-82) in Immunofluorescence

Tue Mar 12 00:00:00 EDT 2019

Adult human pancreatic acinar cells dedifferentiate into an embryonic progenitor-like state in 3D suspension culture.

Scientific reports

Baldan J,Houbracken I,Rooman I,Bouwens L

Published figure using Ki-67 monoclonal antibody (Product # 14-5698-82) in Immunohistochemistry

Mon Mar 11 00:00:00 EDT 2019

Reduced mitochondrial fusion and Huntingtin levels contribute to impaired dendritic maturation and behavioral deficits in Fmr1-mutant mice.

Nature neuroscience

Shen M,Wang F,Li M,Sah N,Stockton ME,Tidei JJ,Gao Y,Korabelnikov T,Kannan S,Vevea JD,Chapman ER,Bhattacharyya A,van Praag H,Zhao X

14-5698-82 was used in Immunohistochemistry to show that FMRP-deficient immature neurons exhibit impaired dendritic maturation, altered expression of mitochondrial genes, fragmented mitochondria, impaired mitochondrial function, and increased oxidative stress.

Fri Mar 01 00:00:00 EST 2019

The nuclear receptor corepressor NCoR1 regulates hematopoiesis and leukemogenesis in vivo.

Blood advances

Wan X,Liu L,Zhou P,Hui X,He Q,Yu F,Zhang W,Ding X,Yuan X,Zhang N,Zhao Y,Zhu R,Liu Y,Hao P,Auwerx J,Song X,Leng Q,Zhang Y

14-5698 was used in Flow cytometry/Cell sorting to identify nuclear receptor corepressor 1 having a key role in murine adult hematopoiesis and its contribution to MLL-AF9 induced leukemogenesis.

Tue Feb 26 00:00:00 EST 2019

C-Kit Cardiac Progenitor Cell Based Cell Sheet Improves Vascularization and Attenuates Cardiac Remodeling following Myocardial Infarction in Rats.

BioMed research international

Dergilev K,Tsokolaeva Z,Makarevich P,Beloglazova I,Zubkova E,Boldyreva M,Ratner E,Dyikanov D,Menshikov M,Ovchinnikov A,Ageev F,Parfyonova Y

Published figure using Ki-67 monoclonal antibody (Product # 14-5698-82) in Immunofluorescence

Mon Jan 14 00:00:00 EST 2019

Comprehensive and cell-type-based characterization of the dorsal midbrain during development.

Genes to cells : devoted to molecular & cellular mechanisms

Arimura N,Dewa KI,Okada M,Yanagawa Y,Taya SI,Hoshino M

Published figure using Ki-67 monoclonal antibody (Product # 14-5698-82) in Immunohistochemistry

Tue Jan 01 00:00:00 EST 2019

Comprehensive and cell-type-based characterization of the dorsal midbrain during development.

Genes to cells : devoted to molecular & cellular mechanisms

Arimura N,Dewa KI,Okada M,Yanagawa Y,Taya SI,Hoshino M

Published figure using Ki-67 monoclonal antibody (Product # 14-5698-82) in Immunohistochemistry

Tue Jan 01 00:00:00 EST 2019

MicroRNA-126 Deficiency Affects the Development of Thymus CD4+ Single-Positive Cells through Elevating IRS-1.

International archives of allergy and immunology

Hu L,Xu H,Lu J,Zhou Y,Chu F,Zheng W,Lei L,Zhao J,Wang H,Guo M,Chen C,Xu L

Published figure using Ki-67 monoclonal antibody (Product # 14-5698-82) in Flow Cytometry

Tue Dec 11 00:00:00 EST 2018

The E3 ligase VHL controls alveolar macrophage function via metabolic-epigenetic regulation.

The Journal of experimental medicine

Zhang W,Li Q,Li D,Li J,Aki D,Liu YC

14-5698 was used in Flow cytometry/Cell sorting to show VHL regulates alveolar macrophages and acts as a crucial egulatory factor in lung inflammation and fibrosis.

Mon Dec 03 00:00:00 EST 2018

ARTS mediates apoptosis and regeneration of the intestinal stem cell niche.

Nature communications

Koren E,Yosefzon Y,Ankawa R,Soteriou D,Jacob A,Nevelsky A,Ben-Yosef R,Bar-Sela G,Fuchs Y

Published figure using Ki-67 monoclonal antibody (Product # 14-5698-82) in Immunofluorescence

Fri Nov 02 00:00:00 EDT 2018

ARTS mediates apoptosis and regeneration of the intestinal stem cell niche.

Nature communications

Koren E,Yosefzon Y,Ankawa R,Soteriou D,Jacob A,Nevelsky A,Ben-Yosef R,Bar-Sela G,Fuchs Y

Published figure using Ki-67 monoclonal antibody (Product # 14-5698-82) in Immunofluorescence

Fri Nov 02 00:00:00 EDT 2018

PPAR-Induced Fatty Acid Oxidation in T Cells Increases the Number of Tumor-Reactive CD8⁺ T Cells and Facilitates Anti-PD-1 Therapy.

Cancer immunology research

Chowdhury PS,Chamoto K,Kumar A,Honjo T

14-5698 was used in Flow cytometry/Cell sorting to study the molecular mechanism of the synergistic effects of bezafibrate on the tumouricidal effects of PD-1 blockade.

Thu Nov 01 00:00:00 EDT 2018

Hoxc-Dependent Mesenchymal Niche Heterogeneity Drives Regional Hair Follicle Regeneration.

Cell stem cell

Yu Z,Jiang K,Xu Z,Huang H,Qian N,Lu Z,Chen D,Di R,Yuan T,Du Z,Xie W,Lu X,Li H,Chai R,Yang Y,Zhu B,Kunieda T,Wang F,Chen T

14-5698 was used in Immunohistochemistry to show that expression of Hoxc genes is sufficient to reprogram mesenchymal DP cells and alter the regenerative potential of epithelial stem cells.

Thu Oct 04 00:00:00 EDT 2018

Defining Lineage Potential and Fate Behavior of Precursors during Pancreas Development.

Developmental cell

Sznurkowska MK,Hannezo E,Azzarelli R,Rulands S,Nestorowa S,Hindley CJ,Nichols J,Göttgens B,Huch M,Philpott A,Simons BD

Published figure using Ki-67 monoclonal antibody (Product # 14-5698-82) in Immunofluorescence

Mon Aug 06 00:00:00 EDT 2018

Defining Lineage Potential and Fate Behavior of Precursors during Pancreas Development.

Developmental cell

Sznurkowska MK,Hannezo E,Azzarelli R,Rulands S,Nestorowa S,Hindley CJ,Nichols J,Göttgens B,Huch M,Philpott A,Simons BD

Published figure using Ki-67 monoclonal antibody (Product # 14-5698-82) in Immunofluorescence

Mon Aug 06 00:00:00 EDT 2018

Identification of dynamic undifferentiated cell states within the male germline.

Nature communications

La HM,Mäkelä JA,Chan AL,Rossello FJ,Nefzger CM,Legrand JMD,De Seram M,Polo JM,Hobbs RM

14-5698 was used in Immunofluorescence in immunohistochemistry on frozen tissues to conclude that Aundiff exist in a series of dynamic cell states with distinct function and provide evidence that stability of such states is dictated by niche-derived cues.

Thu Jul 19 00:00:00 EDT 2018

A Metabolite-Triggered Tuft Cell-ILC2 Circuit Drives Small Intestinal Remodeling.

Cell

Schneider C,O'Leary CE,von Moltke J,Liang HE,Ang QY,Turnbaugh PJ,Radhakrishnan S,Pellizzon M,Ma A,Locksley RM

Published figure using Ki-67 monoclonal antibody (Product # 14-5698-82) in Flow Cytometry

Thu Jul 12 00:00:00 EDT 2018

Cancer Lipid Metabolism Confers Antiangiogenic Drug Resistance.

Cell metabolism

Iwamoto H,Abe M,Yang Y,Cui D,Seki T,Nakamura M,Hosaka K,Lim S,Wu J,He X,Sun X,Lu Y,Zhou Q,Shi W,Torimura T,Nie G,Li Q,Cao Y

14-5698 was used in Immunohistochemistry on paraffin embedded tissues-immunofluorescence to describe AAD-triggered, lipid-dependent metabolic reprogramming as an alternative mechanism of AAD resistance.

Tue Jul 03 00:00:00 EDT 2018

Vitreous Cytokine Expression and a Murine Model Suggest a Key Role of Microglia in the Inflammatory Response to Retinal Detachment.

Investigative ophthalmology & visual science

Kiang L,Ross BX,Yao J,Shanmugam S,Andrews CA,Hansen S,Besirli CG,Zacks DN,Abcouwer SF

Published figure using Ki-67 monoclonal antibody (Product # 14-5698-82) in Immunofluorescence

Mon Jul 02 00:00:00 EDT 2018

p38α blocks brown adipose tissue thermogenesis through p38δ inhibition.

PLoS biology

Matesanz N,Nikolic I,Leiva M,Pulgarín-Alfaro M,Santamans AM,Bernardo E,Mora A,Herrera-Melle L,Rodríguez E,Beiroa D,Caballero A,Martín-García E,Acín-Pérez R,Hernández-Cosido L,Leiva-Vega L,Torres JL,Centeno F,Nebreda AR,Enríquez JA,Nogueiras R,Marcos M,Sabio G

Published figure using Ki-67 monoclonal antibody (Product # 14-5698-82) in Immunohistochemistry

Sun Jul 01 00:00:00 EDT 2018

p38α blocks brown adipose tissue thermogenesis through p38δ inhibition.

PLoS biology

Published figure using Ki-67 monoclonal antibody (Product # 14-5698-82) in Immunohistochemistry

Sun Jul 01 00:00:00 EDT 2018

Stem cell factor is selectively secreted by arterial endothelial cells in bone marrow.

Nature communications

Xu C,Gao X,Wei Q,Nakahara F,Zimmerman SE,Mar J,Frenette PS

Published figure using Ki-67 monoclonal antibody (Product # 14-5698-82) in Flow Cytometry

Fri Jun 22 00:00:00 EDT 2018

The organic ester O,O'-diethyl-(S,S)-ethylenediamine-N,N'-di-2-(3-cyclohexyl)propanoate dihydrochloride attenuates murine breast cancer growth and metastasis.

Oncotarget

Jurisevic M,Arsenijevic A,Pantic J,Gajovic N,Milovanovic J,Milovanovic M,Poljarevic J,Sabo T,Vojvodic D,Radosavljevic GD,Arsenijevic N

Published figure using Ki-67 monoclonal antibody (Product # 14-5698-82) in Flow Cytometry

Fri Jun 15 00:00:00 EDT 2018

Pharmacological activation of epidermal growth factor receptor signaling inhibits colitis-associated cancer in mice.

Scientific reports

Dubé PE,Liu CY,Girish N,Washington MK,Polk DB

Published figure using Ki-67 monoclonal antibody (Product # 14-5698-82) in Immunohistochemistry

Thu Jun 14 00:00:00 EDT 2018

The Epigenetic State of PRDM16-Regulated Enhancers in Radial Glia Controls Cortical Neuron Position.

Neuron

Baizabal JM,Mistry M,García MT,Gómez N,Olukoya O,Tran D,Johnson MB,Walsh CA,Harwell CC

Published figure using Ki-67 monoclonal antibody (Product # 14-5698-82) in Immunohistochemistry

Wed Jun 06 00:00:00 EDT 2018

Adrenergic nerve degeneration in bone marrow drives aging of the hematopoietic stem cell niche.

Nature medicine

Maryanovich M,Zahalka AH,Pierce H,Pinho S,Nakahara F,Asada N,Wei Q,Wang X,Ciero P,Xu J,Leftin A,Frenette PS

Published figure using Ki-67 monoclonal antibody (Product # 14-5698-82) in Flow Cytometry

Fri Jun 01 00:00:00 EDT 2018

Selective pharmacological inhibition of DDR1 prevents experimentally-induced glomerulonephritis in prevention and therapeutic regime.

Journal of translational medicine

Moll S,Yasui Y,Abed A,Murata T,Shimada H,Maeda A,Fukushima N,Kanamori M,Uhles S,Badi L,Cagarelli T,Formentini I,Drawnel F,Georges G,Bergauer T,Gasser R,Bonfil RD,Fridman R,Richter H,Funk J,Moeller MJ,Chatziantoniou C,Prunotto M

Published figure using Ki-67 monoclonal antibody (Product # 14-5698-82) in Immunohistochemistry (Paraffin)

Fri Jun 01 00:00:00 EDT 2018

Selective pharmacological inhibition of DDR1 prevents experimentally-induced glomerulonephritis in prevention and therapeutic regime.

Journal of translational medicine

Published figure using Ki-67 monoclonal antibody (Product # 14-5698-82) in Immunohistochemistry (Paraffin)

Fri Jun 01 00:00:00 EDT 2018

Epithelial Sodium Channel Regulates Adult Neural Stem Cell Proliferation in a Flow-Dependent Manner.

Cell stem cell

Petrik D,Myoga MH,Grade S,Gerkau NJ,Pusch M,Rose CR,Grothe B,Götz M

14-5698 was used in Immunohistochemistry to provide a role for a voltage- and ligandindependent ion channel in adult neurogenesis.

Fri Jun 01 00:00:00 EDT 2018

Single-Cell Transcriptomics and Fate Mapping of Ependymal Cells Reveals an Absence of Neural Stem Cell Function.

Cell

Shah PT,Stratton JA,Stykel MG,Abbasi S,Sharma S,Mayr KA,Koblinger K,Whelan PJ,Biernaskie J

14-5698 was used in Immunohistochemistry to demonstrate stability of ependymal cell function and provide fundamental insights into the molecular signature of the V-SVZ niche.

Thu May 03 00:00:00 EDT 2018

The transcription factor Klf5 is essential for intrahepatic biliary epithelial tissue remodeling after cholestatic liver injury.

The Journal of biological chemistry

Okada H,Yamada M,Kamimoto K,Kok CY,Kaneko K,Ema M,Miyajima A,Itoh T

Published figure using Ki-67 monoclonal antibody (Product # 14-5698-82) in Immunohistochemistry

Fri Apr 27 00:00:00 EDT 2018

Fc Effector Function Contributes to the Activity of Human Anti-CTLA-4 Antibodies.

Cancer cell

Arce Vargas F,Furness AJS,Litchfield K,Joshi K,Rosenthal R,Ghorani E,Solomon I,Lesko MH,Ruef N,Roddie C,Henry JY,Spain L,Ben Aissa A,Georgiou A,Wong YNS,Smith M,Strauss D,Hayes A,Nicol D,O'Brien T,Mårtensson L,Ljungars A,Teige I,Frendéus B,Pule M,Marafioti T,Gore M,Larkin J,Turajlic S,Swanton C,Peggs KS,Quezada SA

Published figure using Ki-67 monoclonal antibody (Product # 14-5698-82) in Flow Cytometry

Mon Apr 09 00:00:00 EDT 2018

Extracellular retention of PDGF-B directs vascular remodeling in mouse hypoxia-induced pulmonary hypertension.

American journal of physiology. Lung cellular and molecular physiology

Tannenberg P,Chang YT,Muhl L,Laviña B,Gladh H,Genové G,Betsholtz C,Folestad E,Tran-Lundmark K

14-5698 was used in Immunohistochemistry-immunofluorescence to emphasize the importance of extracellular matrix-growth factor interactions and adds to previous knowledge of PDGF-B in PH pathobiology.

Sun Apr 01 00:00:00 EDT 2018

Lymphotoxin α fine-tunes T cell clonal deletion by regulating thymic entry of antigen-presenting cells.

Nature communications

Lopes N,Charaix J,Cédile O,Sergé A,Irla M

Published figure using Ki-67 monoclonal antibody (Product # 14-5698-82) in Flow Cytometry

Wed Mar 28 00:00:00 EDT 2018

MicroRNA-126 deficiency enhanced the activation and function of CD4⁺ T cells by elevating IRS-1 pathway.

Clinical and experimental immunology

Chu F,Hu Y,Zhou Y,Guo M,Lu J,Zheng W,Xu H,Zhao J,Xu L

Published figure using Ki-67 monoclonal antibody (Product # 14-5698-82) in Flow Cytometry

Thu Feb 01 00:00:00 EST 2018

Modulation of Myelopoiesis Progenitors Is an Integral Component of Trained Immunity.

Cell

Mitroulis I,Ruppova K,Wang B,Chen LS,Grzybek M,Grinenko T,Eugster A,Troullinaki M,Palladini A,Kourtzelis I,Chatzigeorgiou A,Schlitzer A,Beyer M,Joosten LAB,Isermann B,Lesche M,Petzold A,Simons K,Henry I,Dahl A,Schultze JL,Wielockx B,Zamboni N,Mirtschink P,Coskun Ü,Hajishengallis G,Netea MG,Chavakis T

Published figure using Ki-67 monoclonal antibody (Product # 14-5698-82) in Flow Cytometry

Thu Jan 11 00:00:00 EST 2018

Dual-targeting Wnt and uPA receptors using peptide conjugated ultra-small nanoparticle drug carriers inhibited cancer stem-cell phenotype in chemo-resistant breast cancer.

Biomaterials

Miller-Kleinhenz J,Guo X,Qian W,Zhou H,Bozeman EN,Zhu L,Ji X,Wang YA,Styblo T,O'Regan R,Mao H,Yang L

Published figure using Ki-67 monoclonal antibody (Product # 14-5698-82) in Immunofluorescence

Mon Jan 01 00:00:00 EST 2018

Dual-targeting Wnt and uPA receptors using peptide conjugated ultra-small nanoparticle drug carriers inhibited cancer stem-cell phenotype in chemo-resistant breast cancer.

Biomaterials

Miller-Kleinhenz J,Guo X,Qian W,Zhou H,Bozeman EN,Zhu L,Ji X,Wang YA,Styblo T,O'Regan R,Mao H,Yang L

Published figure using Ki-67 monoclonal antibody (Product # 14-5698-82) in Immunofluorescence

Mon Jan 01 00:00:00 EST 2018

Inhibition of histone deacetylase 1 ameliorates renal tubulointerstitial fibrosis via modulation of inflammation and extracellular matrix gene transcription in mice.

International journal of molecular medicine

Nguyễn-Thanh T,Kim D,Lee S,Kim W,Park SK,Kang KP

Published figure using Ki-67 monoclonal antibody (Product # 14-5698-82) in Immunofluorescence

Mon Jan 01 00:00:00 EST 2018

White Adipose Tissue Is a Reservoir for Memory T Cells and Promotes Protective Memory Responses to Infection.

Immunity

Han SJ,Glatman Zaretsky A,Andrade-Oliveira V,Collins N,Dzutsev A,Shaik J,Morais da Fonseca D,Harrison OJ,Tamoutounour S,Byrd AL,Smelkinson M,Bouladoux N,Bliska JB,Brenchley JM,Brodsky IE,Belkaid Y

Published figure using Ki-67 monoclonal antibody (Product # 14-5698-82) in Flow Cytometry

Tue Dec 19 00:00:00 EST 2017

Longitudinal intravital imaging of the femoral bone marrow reveals plasticity within marrow vasculature.

Nature communications

Reismann D,Stefanowski J,Günther R,Rakhymzhan A,Matthys R,Nützi R,Zehentmeier S,Schmidt-Bleek K,Petkau G,Chang HD,Naundorf S,Winter Y,Melchers F,Duda G,Hauser AE,Niesner RA

14-5698 was used in Immunocytochemistry-immunoflourescence to develop longitudinal intravital imaging of the bone marrow to analyse cellular dynamics within the deep marrow.

Mon Dec 18 00:00:00 EST 2017

A miR-327-FGF10-FGFR2-mediated autocrine signaling mechanism controls white fat browning.

Nature communications

Fischer C,Seki T,Lim S,Nakamura M,Andersson P,Yang Y,Honek J,Wang Y,Gao Y,Chen F,Samani NJ,Zhang J,Miyake M,Oyadomari S,Yasue A,Li X,Zhang Y,Liu Y,Cao Y

14-5698 was used in Immunohistochemistry to provide mechanistic insight into an autocrine regulatory signalling loop that regulates beige adipocyte formation.

Tue Dec 12 00:00:00 EST 2017

Organoids model distinct Vitamin E effects at different stages of prostate cancer evolution.

Scientific reports

Njoroge RN,Unno K,Zhao JC,Naseem AF,Anker JF,McGee WA,Nonn L,Abdulkadir SA

14-5698 was used in Immunohistochemistry-immunofluorescence to demonstrate using organoid models that Vitamin E promotes tumorigenesis in the early stages of prostate cancer evolution.

Fri Nov 24 00:00:00 EST 2017

Melanocyte Stem Cell Activation and Translocation Initiate Cutaneous Melanoma in Response to UV Exposure.

Cell stem cell

Moon H,Donahue LR,Choi E,Scumpia PO,Lowry WE,Grenier JK,Zhu J,White AC

14-5698 was used in Immunohistochemistry-immunofluorescence to define the role of melanocyte stem cells as melanoma cells of origin, and identify the extrinsic factors required for the critical early steps of melanoma initiation.

Thu Nov 02 00:00:00 EDT 2017

High fat diet exacerbates murine psoriatic dermatitis by increasing the number of IL-17-producing γδ T cells.

Scientific reports

Nakamizo S,Honda T,Adachi A,Nagatake T,Kunisawa J,Kitoh A,Otsuka A,Dainichi T,Nomura T,Ginhoux F,Ikuta K,Egawa G,Kabashima K

14-5698 was used in Flow cytometry/Cell sorting to indicate that HFD is a key element in exacerbation of IMQ-induced psoriatic dermatitis, and further raise the possibility of HFD as a factor that links obesity and psoriasis.

Thu Oct 26 00:00:00 EDT 2017

LINC00461, a long non-coding RNA, is important for the proliferation and migration of glioma cells.

Oncotarget

Yang Y,Ren M,Song C,Li D,Soomro SH,Xiong Y,Zhang H,Fu H

14-5698 was used in Immunofluorescence to show that LINC00461 long non-coding RNA is highly expressed in glioma tissues and is important for glioma progression.

Fri Oct 13 00:00:00 EDT 2017

Neonatal pancreatic pericytes support β-cell proliferation.

Molecular metabolism

Epshtein A,Rachi E,Sakhneny L,Mizrachi S,Baer D,Landsman L

Published figure using Ki-67 monoclonal antibody (Product # 14-5698-82) in Flow Cytometry

Sun Oct 01 00:00:00 EDT 2017

The Ror1 receptor tyrosine kinase plays a critical role in regulating satellite cell proliferation during regeneration of injured muscle.

The Journal of biological chemistry

Kamizaki K,Doi R,Hayashi M,Saji T,Kanagawa M,Toda T,Fukada SI,Ho HH,Greenberg ME,Endo M,Minami Y

Published figure using Ki-67 monoclonal antibody (Product # 14-5698-82) in Immunocytochemistry

Fri Sep 22 00:00:00 EDT 2017

The Ror1 receptor tyrosine kinase plays a critical role in regulating satellite cell proliferation during regeneration of injured muscle.

The Journal of biological chemistry

Kamizaki K,Doi R,Hayashi M,Saji T,Kanagawa M,Toda T,Fukada SI,Ho HH,Greenberg ME,Endo M,Minami Y

Published figure using Ki-67 monoclonal antibody (Product # 14-5698-82) in Immunocytochemistry

Fri Sep 22 00:00:00 EDT 2017

A somatic mutation in erythro-myeloid progenitors causes neurodegenerative disease.

Nature

Mass E,Jacome-Galarza CE,Blank T,Lazarov T,Durham BH,Ozkaya N,Pastore A,Schwabenland M,Chung YR,Rosenblum MK,Prinz M,Abdel-Wahab O,Geissmann F

Published figure using Ki-67 monoclonal antibody (Product # 14-5698-82) in Flow Cytometry

Thu Sep 21 00:00:00 EDT 2017

Erythropoietin enhances Kupffer cell number and activity in the challenged liver.

Scientific reports

Gilboa D,Haim-Ohana Y,Deshet-Unger N,Ben-Califa N,Hiram-Bab S,Reuveni D,Zigmond E,Gassmann M,Gabet Y,Varol C,Neumann D

Published figure using Ki-67 monoclonal antibody (Product # 14-5698-82) in Flow Cytometry

Mon Sep 04 00:00:00 EDT 2017

Preclinical Development of Ipilimumab and Nivolumab Combination Immunotherapy: Mouse Tumor Models, In Vitro Functional Studies, and Cynomolgus Macaque Toxicology.

PloS one

Selby MJ,Engelhardt JJ,Johnston RJ,Lu LS,Han M,Thudium K,Yao D,Quigley M,Valle J,Wang C,Chen B,Cardarelli PM,Blanset D,Korman AJ

14-5698 was used in Flow cytometry/Cell sorting to exhibit a preclinical strategy for the identification and development of highly effective antitumour combination immunotherapies.

Fri Aug 25 00:00:00 EDT 2017

The Ox40/Ox40 Ligand Pathway Promotes Pathogenic Th Cell Responses, Plasmablast Accumulation, and Lupus Nephritis in NZB/W F1 Mice.

Journal of immunology (Baltimore, Md. : 1950)

Sitrin J,Suto E,Wuster A,Eastham-Anderson J,Kim JM,Austin CD,Lee WP,Behrens TW

14-5698 was used in Flow cytometry/Cell sorting to support the hypothesis that the Ox40/Ox40L pathway drives cellular and humoral autoimmune responses during lupus nephritis in NZB/W F1.

Tue Aug 15 00:00:00 EDT 2017

Myelination is delayed during postnatal brain development in the mdx mouse model of Duchenne muscular dystrophy.

BMC neuroscience

Aranmolate A,Tse N,Colognato H

14-5698 was used in Immunohistochemistry to find that dystrophin is expressed in oligodendrocytes and influences developmental myelination important in finding potential contributors to brain dysfunction in DMD.

Mon Aug 14 00:00:00 EDT 2017

Mitogenic stimulation accelerates influenza-induced mortality by increasing susceptibility of alveolar type II cells to infection.

Proceedings of the National Academy of Sciences of the United States of America

Nikolaidis NM,Noel JG,Pitstick LB,Gardner JC,Uehara Y,Wu H,Saito A,Lewnard KE,Liu H,White MR,Hartshorn KL,McCormack FX

14-5698 was used in Flow cytometry/Cell sorting to investigate the role of mitogenic stimulation in susceptibility to pneumonia.

Tue Aug 08 00:00:00 EDT 2017

Modeling African American prostate adenocarcinoma by inducing defined genetic alterations in organoids.

Oncotarget

Unno K,Roh M,Yoo YA,Al-Shraideh Y,Wang L,Nonn L,Abdulkadir SA

Published figure using Ki-67 monoclonal antibody (Product # 14-5698-82) in Immunofluorescence

Tue Aug 01 00:00:00 EDT 2017

Mutations in 5-methylcytosine oxidase TET2 and RhoA cooperatively disrupt T cell homeostasis.

The Journal of clinical investigation

Zang S,Li J,Yang H,Zeng H,Han W,Zhang J,Lee M,Moczygemba M,Isgandarova S,Yang Y,Zhou Y,Rao A,You MJ,Sun D,Huang Y

Published figure using Ki-67 monoclonal antibody (Product # 14-5698-82) in Flow Cytometry

Tue Aug 01 00:00:00 EDT 2017

Inhibition of the B7-H3 immune checkpoint limits tumor growth by enhancing cytotoxic lymphocyte function.

Cell research

Lee YH,Martin-Orozco N,Zheng P,Li J,Zhang P,Tan H,Park HJ,Jeong M,Chang SH,Kim BS,Xiong W,Zang W,Guo L,Liu Y,Dong ZJ,Overwijk WW,Hwu P,Yi Q,Kwak L,Yang Z,Mak TW,Li W,Radvanyi LG,Ni L,Liu D,Dong C

14-5698 was used in Flow cytometry/Cell sorting to indicate that the B7-H3 checkpoint may serve as a novel target for immunotherapy against cancer.

Tue Aug 01 00:00:00 EDT 2017

IL-4 as a Repurposed Biological Drug for Myocardial Infarction through Augmentation of Reparative Cardiac Macrophages: Proof-of-Concept Data in Mice.

Scientific reports

Shintani Y,Ito T,Fields L,Shiraishi M,Ichihara Y,Sato N,Podaru M,Kainuma S,Tanaka H,Suzuki K

Published figure using Ki-67 monoclonal antibody (Product # 14-5698-82) in Immunofluorescence

Mon Jul 31 00:00:00 EDT 2017

De Novo Epigenetic Programs Inhibit PD-1 Blockade-Mediated T Cell Rejuvenation.

Cell

Ghoneim HE,Fan Y,Moustaki A,Abdelsamed HA,Dash P,Dogra P,Carter R,Awad W,Neale G,Thomas PG,Youngblood B

Published figure using Ki-67 monoclonal antibody (Product # 14-5698-82) in Flow Cytometry

Thu Jun 29 00:00:00 EDT 2017

Maintenance of antiangiogenic and antitumor effects by orally active low-dose capecitabine for long-term cancer therapy.

Proceedings of the National Academy of Sciences of the United States of America

Zhang Y,Sun M,Huang G,Yin L,Lai Q,Yang Y,Xing X,Yu G,Sun Y,Wang X,Nie G,Liu Y,Cao Y

14-5698 was used in Immunohistochemistry-immunofluorescence to provide a rationalized concept of effective cancer therapy by long-term maintenance of AAD-triggered antiangiogenic effects with orally active, nontoxic, low-cost, clinically available chemotherapeutics.

Tue Jun 27 00:00:00 EDT 2017

Deletion of PIKfyve alters alveolar macrophage populations and exacerbates allergic inflammation in mice.

The EMBO journal

Kawasaki T,Ito K,Miyata H,Akira S,Kawai T

Published figure using Ki-67 monoclonal antibody (Product # 14-5698-82) in Flow Cytometry

Wed Jun 14 00:00:00 EDT 2017

Egr2 and 3 control adaptive immune responses by temporally uncoupling expansion from T cell differentiation.

The Journal of experimental medicine

Miao T,Symonds ALJ,Singh R,Symonds JD,Ogbe A,Omodho B,Zhu B,Li S,Wang P

Published figure using Ki-67 monoclonal antibody (Product # 14-5698-82) in Flow Cytometry

Mon Jun 05 00:00:00 EDT 2017

PD-1 regulates KLRG1⁺ group 2 innate lymphoid cells.

The Journal of experimental medicine

Taylor S,Huang Y,Mallett G,Stathopoulou C,Felizardo TC,Sun MA,Martin EL,Zhu N,Woodward EL,Elias MS,Scott J,Reynolds NJ,Paul WE,Fowler DH,Amarnath S

14-5698-82 was used in Flow Cytometry to report that PD-1 is required for maintaining the number, and hence function, of KLRG1+ Group 2 innate lymphoid cells.

Mon Jun 05 00:00:00 EDT 2017

Administration of RANKL boosts thymic regeneration upon bone marrow transplantation.

EMBO molecular medicine

Lopes N,Vachon H,Marie J,Irla M

14-5698 was used in Flow cytometry/Cell sorting to indicate that RANKL may be clinically useful to improve T-cell function recovery after bone marrow transplantation by controlling multiple facets of thymic regeneration.

Thu Jun 01 00:00:00 EDT 2017

Cell-Cycle Regulation Accounts for Variability in Ki-67 Expression Levels.

Cancer research

Sobecki M,Mrouj K,Colinge J,Gerbe F,Jay P,Krasinska L,Dulic V,Fisher D

14-5698 was used in Immunofluorescence to explain that the variability of Ki-67 expression is due to cell-cycle regulation.

Mon May 15 00:00:00 EDT 2017

Histone variant H2A.J accumulates in senescent cells and promotes inflammatory gene expression.

Nature communications

Contrepois K,Coudereau C,Benayoun BA,Schuler N,Roux PF,Bischof O,Courbeyrette R,Carvalho C,Thuret JY,Ma Z,Derbois C,Nevers MC,Volland H,Redon CE,Bonner WM,Deleuze JF,Wiel C,Bernard D,Snyder MP,Rübe CE,Olaso R,Fenaille F,Mann C

Published figure using Ki-67 monoclonal antibody (Product # 14-5698-82) in Immunofluorescence

Wed May 10 00:00:00 EDT 2017

A coordinated DNA damage response promotes adult quiescent neural stem cell activation.

PLoS biology

Barazzuol L,Ju L,Jeggo PA

14-5698 was used in Immunohistochemistry-immunofluorescence to show distinct responses to ionising radiation between neural stem and progenitor cells.

Mon May 01 00:00:00 EDT 2017

The Major Histocompatibility Complex Class III Haplotype Ltab-Ncr3 Regulates Adjuvant-Induced but Not Antigen-Induced Autoimmunity.

The American journal of pathology

Yau ACY,Tuncel J,Holmdahl R

14-5698 was used in Flow cytometry/Cell sorting to find that Ltab-Ncr3 is specific in regulating adjuvant-induced arthritis but not antigen-induced autoimmunity.

Mon May 01 00:00:00 EDT 2017

Peg3/PW1 Is a Marker of a Subset of Vessel Associated Endothelial Progenitors.

Stem cells (Dayton, Ohio)

Malinverno M,Corada M,Ferrarini L,Formicola L,Marazzi G,Sassoon D,Dejana E

14-5698 was used in Immunofluorescence to identify a subset of vessel associated endothelial cells with characteristics of progenitor cells.

Mon May 01 00:00:00 EDT 2017

Glucose-Dependent Insulinotropic Polypeptide Receptor Deficiency Leads to Impaired Bone Marrow Hematopoiesis.

Journal of immunology (Baltimore, Md. : 1950)

Mantelmacher FD,Fishman S,Cohen K,Pasmanik Chor M,Yamada Y,Zvibel I,Varol C

14-5698 was used in Flow cytometry/Cell sorting to show that significantly reduced representation and proliferation of hematopoietic stem and progenitor cells and myeloid progenitors in the bone marrow of Gipr-/- mice.

Sat Apr 15 00:00:00 EDT 2017

Myeloid progenitor cluster formation drives emergency and leukaemic myelopoiesis.

Nature

Hérault A,Binnewies M,Leong S,Calero-Nieto FJ,Zhang SY,Kang YA,Wang X,Pietras EM,Chu SH,Barry-Holson K,Armstrong S,Göttgens B,Passegué E

Published figure using Ki-67 monoclonal antibody (Product # 14-5698-82) in Flow Cytometry

Thu Apr 06 00:00:00 EDT 2017

Differential cytokine contributions of perivascular haematopoietic stem cell niches.

Nature cell biology

Asada N,Kunisaki Y,Pierce H,Wang Z,Fernandez NF,Birbrair A,Ma'ayan A,Frenette PS

Published figure using Ki-67 monoclonal antibody (Product # 14-5698-82) in Flow Cytometry

Wed Mar 01 00:00:00 EST 2017

The transcription factor musculin promotes the unidirectional development of peripheral T_reg cells by suppressing the T_H2 transcriptional program.

Nature immunology

Wu C,Chen Z,Dardalhon V,Xiao S,Thalhamer T,Liao M,Madi A,Franca RF,Han T,Oukka M,Kuchroo V

14-5698 was used in Flow cytometry/Cell sorting to identify the TF Musculin (MSC) as critical for iTreg development by repression of TH2 transcriptional program, using Transforming growth factor-β (TGF-β) induced regulatory T cell (iTreg) system.

Wed Mar 01 00:00:00 EST 2017

p53 Modulates the Fate of Cardiac Progenitor Cells Ex Vivo and in the Diabetic Heart In Vivo.

EBioMedicine

Kannappan R,Matsuda A,Ferreira-Martins J,Zhang E,Palano G,Czarna A,Cabral-Da-Silva MC,Bastos-Carvalho A,Sanada F,Ide N,Rota M,Blasco MA,Serrano M,Anversa P,Leri A

14-5698 was used in Immunocytochemistry-immunoflourescence to study the effects of a single extra-copy of p53 on cardiac progenitor cell function in the presence of oxidative stress.

Wed Feb 01 00:00:00 EST 2017

Foxp3 and Toll-like receptor signaling balance T_reg cell anabolic metabolism for suppression.

Nature immunology

Gerriets VA,Kishton RJ,Johnson MO,Cohen S,Siska PJ,Nichols AG,Warmoes MO,de Cubas AA,MacIver NJ,Locasale JW,Turka LA,Wells AD,Rathmell JC

Published figure using Ki-67 monoclonal antibody (Product # 14-5698-82) in Flow Cytometry

Thu Dec 01 00:00:00 EST 2016

Hyaluronan and TLR4 promote surfactant-protein-C-positive alveolar progenitor cell renewal and prevent severe pulmonary fibrosis in mice.

Nature medicine

Liang J,Zhang Y,Xie T,Liu N,Chen H,Geng Y,Kurkciyan A,Mena JM,Stripp BR,Jiang D,Noble PW

Published figure using Ki-67 monoclonal antibody (Product # 14-5698-82) in Immunocytochemistry

Tue Nov 01 00:00:00 EDT 2016

Large tumor suppressor homologs 1 and 2 regulate mouse liver progenitor cell proliferation and maturation through antagonism of the coactivators YAP and TAZ.

Hepatology (Baltimore, Md.)

Yi J,Lu L,Yanger K,Wang W,Sohn BH,Stanger BZ,Zhang M,Martin JF,Ajani JA,Chen J,Lee JS,Song S,Johnson RL

14-5698 was used in Immunohistochemistry on paraffin embedded tissues-immunofluorescence to study the role of Hippo signalling pathway kinases, large tumour suppressor homologues 1 and 2, during mouse liver development.

Tue Nov 01 00:00:00 EDT 2016

Whole Chromosome Instability induces senescence and promotes SASP.

Scientific reports

Andriani GA,Almeida VP,Faggioli F,Mauro M,Tsai WL,Santambrogio L,Maslov A,Gadina M,Campisi J,Vijg J,Montagna C

Published figure using Ki-67 monoclonal antibody (Product # 14-5698-82) in Immunofluorescence

Wed Oct 12 00:00:00 EDT 2016

Whole Chromosome Instability induces senescence and promotes SASP.

Scientific reports

Andriani GA,Almeida VP,Faggioli F,Mauro M,Tsai WL,Santambrogio L,Maslov A,Gadina M,Campisi J,Vijg J,Montagna C

Published figure using Ki-67 monoclonal antibody (Product # 14-5698-82) in Immunofluorescence

Wed Oct 12 00:00:00 EDT 2016

Host-Protozoan Interactions Protect from Mucosal Infections through Activation of the Inflammasome.

Cell

Chudnovskiy A,Mortha A,Kana V,Kennard A,Ramirez JD,Rahman A,Remark R,Mogno I,Ng R,Gnjatic S,Amir ED,Solovyov A,Greenbaum B,Clemente J,Faith J,Belkaid Y,Grigg ME,Merad M

Published figure using Ki-67 monoclonal antibody (Product # 14-5698-82) in Immunofluorescence

Thu Oct 06 00:00:00 EDT 2016

Macrophages transfer antigens to dendritic cells by releasing exosomes containing dead-cell-associated antigens partially through a ceramide-dependent pathway to enhance CD4(+) T-cell responses.

Immunology

Xu Y,Liu Y,Yang C,Kang L,Wang M,Hu J,He H,Song W,Tang H

Published figure using Ki-67 monoclonal antibody (Product # 14-5698-82) in Flow Cytometry

Sat Oct 01 00:00:00 EDT 2016

Proliferation and Recruitment Contribute to Myocardial Macrophage Expansion in Chronic Heart Failure.

Circulation research

Sager HB,Hulsmans M,Lavine KJ,Moreira MB,Heidt T,Courties G,Sun Y,Iwamoto Y,Tricot B,Khan OF,Dahlman JE,Borodovsky A,Fitzgerald K,Anderson DG,Weissleder R,Libby P,Swirski FK,Nahrendorf M

14-5698 was used in Flow cytometry/Cell sorting to elucidate the origin and roles of macrophages in the post-myocardial infarction remodelling of nonischaemic remote myocardium.

Fri Sep 16 00:00:00 EDT 2016

Schwann cell proliferation and differentiation that is induced by ferulic acid through MEK1/ERK1/2 signalling promotes peripheral nerve remyelination following crush injury in rats.

Experimental and therapeutic medicine

Zhu X,Li K,Guo X,Wang J,Xiang Y

Published figure using Ki-67 monoclonal antibody (Product # 14-5698-82) in Flow Cytometry

Thu Sep 01 00:00:00 EDT 2016

Suppression of ischemia in arterial occlusive disease by JNK-promoted native collateral artery development.

eLife

Ramo K,Sugamura K,Craige S,Keaney JF,Davis RJ

Published figure using Ki-67 monoclonal antibody (Product # 14-5698-82) in Immunofluorescence

Tue Aug 09 00:00:00 EDT 2016

Heterogeneous fibroblasts underlie age-dependent tertiary lymphoid tissues in the kidney.

JCI insight

Sato Y,Mii A,Hamazaki Y,Fujita H,Nakata H,Masuda K,Nishiyama S,Shibuya S,Haga H,Ogawa O,Shimizu A,Narumiya S,Kaisho T,Arita M,Yanagisawa M,Miyasaka M,Sharma K,Minato N,Kawamoto H,Yanagita M

Published figure using Ki-67 monoclonal antibody (Product # 14-5698-82) in Immunohistochemistry

Thu Jul 21 00:00:00 EDT 2016

Heterogeneous fibroblasts underlie age-dependent tertiary lymphoid tissues in the kidney.

JCI insight

Sato Y,Mii A,Hamazaki Y,Fujita H,Nakata H,Masuda K,Nishiyama S,Shibuya S,Haga H,Ogawa O,Shimizu A,Narumiya S,Kaisho T,Arita M,Yanagisawa M,Miyasaka M,Sharma K,Minato N,Kawamoto H,Yanagita M

Published figure using Ki-67 monoclonal antibody (Product # 14-5698-82) in Immunohistochemistry

Thu Jul 21 00:00:00 EDT 2016

Detection of Cell Proliferation Markers by Immunofluorescence Staining and Microscopy Imaging in Paraffin-Embedded Tissue Sections.

Current protocols in molecular biology

Eminaga S,Teekakirikul P,Seidman CE,Seidman JG

Published figure using Ki-67 monoclonal antibody (Product # 14-5698-82) in Immunofluorescence

Fri Jul 01 00:00:00 EDT 2016

RANKL/RANK control Brca1 mutation- .

Cell research

Sigl V,Owusu-Boaitey K,Joshi PA,Kavirayani A,Wirnsberger G,Novatchkova M,Kozieradzki I,Schramek D,Edokobi N,Hersl J,Sampson A,Odai-Afotey A,Lazaro C,Gonzalez-Suarez E,Pujana MA,Cimba F,Heyn H,Vidal E,Cruickshank J,Berman H,Sarao R,Ticevic M,Uribesalgo I,Tortola L,Rao S,Tan Y,Pfeiler G,Lee EY,Bago-Horvath Z,Kenner L,Popper H,Singer C,Khokha R,Jones LP,Penninger JM

Published figure using Ki-67 monoclonal antibody (Product # 14-5698-82) in Immunohistochemistry

Fri Jul 01 00:00:00 EDT 2016

Accelerating skin wound healing by M-CSF through generating SSEA-1 and -3 stem cells in the injured sites.

Scientific reports

Li Y,Jalili RB,Ghahary A

14-5698 was used in Immunofluorescence to demonstrate that M-CSF induces hematopoietic cell dedifferentiation into SSEA-1 and -3 stem cells, accelerating skin wound healing.

Fri Jul 01 00:00:00 EDT 2016

Cardiac Fibro-Adipocyte Progenitors Express Desmosome Proteins and Preferentially Differentiate to Adipocytes Upon Deletion of the Desmoplakin Gene.

Circulation research

Lombardi R,Chen SN,Ruggiero A,Gurha P,Czernuszewicz GZ,Willerson JT,Marian AJ

14569882 was used in immunohistochemistry - paraffin section to discuss the cellular origins of fibroadipocytes in arrhythmogenic cardiomyopathy

Fri Jun 24 00:00:00 EDT 2016

Image-based detection and targeting of therapy resistance in pancreatic adenocarcinoma.

Nature

Fox RG,Lytle NK,Jaquish DV,Park FD,Ito T,Bajaj J,Koechlein CS,Zimdahl B,Yano M,Kopp J,Kritzik M,Sicklick J,Sander M,Grandgenett PM,Hollingsworth MA,Shibata S,Pizzo D,Valasek M,Sasik R,Scadeng M,Okano H,Kim Y,MacLeod AR,Lowy AM,Reya T

Published figure using Ki-67 monoclonal antibody (Product # 14-5698-82) in Immunofluorescence

Thu Jun 16 00:00:00 EDT 2016

Image-based detection and targeting of therapy resistance in pancreatic adenocarcinoma.

Nature

Published figure using Ki-67 monoclonal antibody (Product # 14-5698-82) in Immunofluorescence

Thu Jun 16 00:00:00 EDT 2016

Rad18 confers hematopoietic progenitor cell DNA damage tolerance independently of the Fanconi Anemia pathway in vivo.

Nucleic acids research

Yang Y,Poe JC,Yang L,Fedoriw A,Desai S,Magnuson T,Li Z,Fedoriw Y,Araki K,Gao Y,Tateishi S,Sarantopoulos S,Vaziri C

14-5698-82 was used in Flow Cytometry to investigate the physiological roles of Rad18 in DNA damage tolerance and carcinogenesis.

Thu May 19 00:00:00 EDT 2016

Incomplete clonal deletion as prerequisite for tissue-specific minor antigen tolerization.

JCI insight

Pilat N,Mahr B,Unger L,Hock K,Schwarz C,Farkas AM,Baranyi U,Wrba F,Wekerle T

14-5698 was used in Flow cytometry/Cell sorting to suggest that deletion of donor-reactive T cells for specificities expressed on hematopoietic cells preclude the expansion of donor-specific Tregs.

Thu May 19 00:00:00 EDT 2016

Immune response modulation by Galectin-1 in a transgenic model of neuroblastoma.

Oncoimmunology

Büchel G,Schulte JH,Harrison L,Batzke K,Schüller U,Hansen W,Schramm A

Published figure using Ki-67 monoclonal antibody (Product # 14-5698-82) in Flow Cytometry

Sun May 01 00:00:00 EDT 2016

The cell proliferation antigen Ki-67 organises heterochromatin.

eLife

Sobecki M,Mrouj K,Camasses A,Parisis N,Nicolas E,Llères D,Gerbe F,Prieto S,Krasinska L,David A,Eguren M,Birling MC,Urbach S,Hem S,Déjardin J,Malumbres M,Jay P,Dulic V,Lafontaine DLj,Feil R,Fisher D

Published figure using Ki-67 monoclonal antibody (Product # 14-5698-82) in Flow Cytometry

Mon Mar 07 00:00:00 EST 2016

The cell proliferation antigen Ki-67 organises heterochromatin.

eLife

Sobecki M,Mrouj K,Camasses A,Parisis N,Nicolas E,Llères D,Gerbe F,Prieto S,Krasinska L,David A,Eguren M,Birling MC,Urbach S,Hem S,Déjardin J,Malumbres M,Jay P,Dulic V,Lafontaine DLj,Feil R,Fisher D

Published figure using Ki-67 monoclonal antibody (Product # 14-5698-82) in Flow Cytometry

Mon Mar 07 00:00:00 EST 2016

The cell proliferation antigen Ki-67 organises heterochromatin.

eLife

Sobecki M,Mrouj K,Camasses A,Parisis N,Nicolas E,Llères D,Gerbe F,Prieto S,Krasinska L,David A,Eguren M,Birling MC,Urbach S,Hem S,Déjardin J,Malumbres M,Jay P,Dulic V,Lafontaine DLj,Feil R,Fisher D

Published figure using Ki-67 monoclonal antibody (Product # 14-5698-82) in Flow Cytometry

Mon Mar 07 00:00:00 EST 2016

The cell proliferation antigen Ki-67 organises heterochromatin.

eLife

Sobecki M,Mrouj K,Camasses A,Parisis N,Nicolas E,Llères D,Gerbe F,Prieto S,Krasinska L,David A,Eguren M,Birling MC,Urbach S,Hem S,Déjardin J,Malumbres M,Jay P,Dulic V,Lafontaine DLj,Feil R,Fisher D

Published figure using Ki-67 monoclonal antibody (Product # 14-5698-82) in Flow Cytometry

Mon Mar 07 00:00:00 EST 2016

The cell proliferation antigen Ki-67 organises heterochromatin.

eLife

Sobecki M,Mrouj K,Camasses A,Parisis N,Nicolas E,Llères D,Gerbe F,Prieto S,Krasinska L,David A,Eguren M,Birling MC,Urbach S,Hem S,Déjardin J,Malumbres M,Jay P,Dulic V,Lafontaine DLj,Feil R,Fisher D

Published figure using Ki-67 monoclonal antibody (Product # 14-5698-82) in Flow Cytometry

Mon Mar 07 00:00:00 EST 2016

The cell proliferation antigen Ki-67 organises heterochromatin.

eLife

Sobecki M,Mrouj K,Camasses A,Parisis N,Nicolas E,Llères D,Gerbe F,Prieto S,Krasinska L,David A,Eguren M,Birling MC,Urbach S,Hem S,Déjardin J,Malumbres M,Jay P,Dulic V,Lafontaine DLj,Feil R,Fisher D

Published figure using Ki-67 monoclonal antibody (Product # 14-5698-82) in Flow Cytometry

Mon Mar 07 00:00:00 EST 2016

The cell proliferation antigen Ki-67 organises heterochromatin.

eLife

Sobecki M,Mrouj K,Camasses A,Parisis N,Nicolas E,Llères D,Gerbe F,Prieto S,Krasinska L,David A,Eguren M,Birling MC,Urbach S,Hem S,Déjardin J,Malumbres M,Jay P,Dulic V,Lafontaine DLj,Feil R,Fisher D

Published figure using Ki-67 monoclonal antibody (Product # 14-5698-82) in Flow Cytometry

Mon Mar 07 00:00:00 EST 2016

The cell proliferation antigen Ki-67 organises heterochromatin.

eLife

Sobecki M,Mrouj K,Camasses A,Parisis N,Nicolas E,Llères D,Gerbe F,Prieto S,Krasinska L,David A,Eguren M,Birling MC,Urbach S,Hem S,Déjardin J,Malumbres M,Jay P,Dulic V,Lafontaine DLj,Feil R,Fisher D

Published figure using Ki-67 monoclonal antibody (Product # 14-5698-82) in Flow Cytometry

Mon Mar 07 00:00:00 EST 2016

Lineage-specific enhancers activate self-renewal genes in macrophages and embryonic stem cells.

Science (New York, N.Y.)

Soucie EL,Weng Z,Geirsdóttir L,Molawi K,Maurizio J,Fenouil R,Mossadegh-Keller N,Gimenez G,VanHille L,Beniazza M,Favret J,Berruyer C,Perrin P,Hacohen N,Andrau JC,Ferrier P,Dubreuil P,Sidow A,Sieweke MH

Published figure using Ki-67 monoclonal antibody (Product # 14-5698-82) in Immunofluorescence

Fri Feb 12 00:00:00 EST 2016

Differential Responsiveness of Innate-like IL-17- and IFN-γ-Producing γδ T Cells to Homeostatic Cytokines.

Journal of immunology (Baltimore, Md. : 1950)

Corpuz TM,Stolp J,Kim HO,Pinget GV,Gray DH,Cho JH,Sprent J,Webster KE

14-5698 was used in Flow cytometry/Cell sorting to suggest that γδ T cell subsets do not directly compete with each other for cytokines, but instead fall into resource niches with other functionally similar lymphocytes.

Fri Jan 15 00:00:00 EST 2016

Oligodendrocyte death results in immune-mediated CNS demyelination.

Nature neuroscience

Traka M,Podojil JR,McCarthy DP,Miller SD,Popko B

Published figure using Ki-67 monoclonal antibody (Product # 14-5698-82) in Flow Cytometry

Fri Jan 01 00:00:00 EST 2016

Imaging Macrophage and Hematopoietic Progenitor Proliferation in Atherosclerosis.

Circulation research

Ye YX,Calcagno C,Binderup T,Courties G,Keliher EJ,Wojtkiewicz GR,Iwamoto Y,Tang J,Pérez-Medina C,Mani V,Ishino S,Johnbeck CB,Knigge U,Fayad ZA,Libby P,Weissleder R,Tawakol A,Dubey S,Belanger AP,Di Carli MF,Swirski FK,Kjaer A,Mulder WJ,Nahrendorf M

14-5698 was used in Immunohistochemistry to performF-FLT positron emission tomography-computed tomography was performed in mice, rabbits, and humans with atherosclerosis.

Fri Oct 23 00:00:00 EDT 2015

Low levels of endogenous or X-ray-induced DNA double-strand breaks activate apoptosis in adult neural stem cells.

Journal of cell science

Barazzuol L,Rickett N,Ju L,Jeggo PA

Published figure using Ki-67 monoclonal antibody (Product # 14-5698-82) in Immunofluorescence

Thu Oct 01 00:00:00 EDT 2015

Mammary Stem Cells and Tumor-Initiating Cells Are More Resistant to Apoptosis and Exhibit Increased DNA Repair Activity in Response to DNA Damage.

Stem cell reports

Chang CH,Zhang M,Rajapakshe K,Coarfa C,Edwards D,Huang S,Rosen JM

Published figure using Ki-67 monoclonal antibody (Product # 14-5698-82) in Flow Cytometry

Tue Sep 08 00:00:00 EDT 2015

Epithelial-to-mesenchymal transition induces cell cycle arrest and parenchymal damage in renal fibrosis.

Nature medicine

Lovisa S,LeBleu VS,Tampe B,Sugimoto H,Vadnagara K,Carstens JL,Wu CC,Hagos Y,Burckhardt BC,Pentcheva-Hoang T,Nischal H,Allison JP,Zeisberg M,Kalluri R

Published figure using Ki-67 monoclonal antibody (Product # 14-5698-82) in Immunofluorescence

Tue Sep 01 00:00:00 EDT 2015

Inhibition of System Xc(-) Transporter Attenuates Autoimmune Inflammatory Demyelination.

Journal of immunology (Baltimore, Md. : 1950)

Evonuk KS,Baker BJ,Doyle RE,Moseley CE,Sestero CM,Johnston BP,De Sarno P,Tang A,Gembitsky I,Hewett SJ,Weaver CT,Raman C,DeSilva TM

14-5698 was used in Flow cytometry/Cell sorting to investigate the link between inflammation and glutamate dysregulation in EAE, showing that inhibition of system Xc(-) transporter attenuates autoimmune inflammatory demyelination.

Wed Jul 15 00:00:00 EDT 2015

NF-κB-induced microRNA-31 promotes epidermal hyperplasia by repressing protein phosphatase 6 in psoriasis.

Nature communications

Yan S,Xu Z,Lou F,Zhang L,Ke F,Bai J,Liu Z,Liu J,Wang H,Zhu H,Sun Y,Cai W,Gao Y,Su B,Li Q,Yang X,Yu J,Lai Y,Yu XZ,Zheng Y,Shen N,Chin YE,Wang H

Published figure using Ki-67 monoclonal antibody (Product # 14-5698-82) in Immunohistochemistry

Fri Jul 03 00:00:00 EDT 2015

NF-κB-induced microRNA-31 promotes epidermal hyperplasia by repressing protein phosphatase 6 in psoriasis.

Nature communications

Yan S,Xu Z,Lou F,Zhang L,Ke F,Bai J,Liu Z,Liu J,Wang H,Zhu H,Sun Y,Cai W,Gao Y,Su B,Li Q,Yang X,Yu J,Lai Y,Yu XZ,Zheng Y,Shen N,Chin YE,Wang H

Published figure using Ki-67 monoclonal antibody (Product # 14-5698-82) in Immunohistochemistry

Fri Jul 03 00:00:00 EDT 2015

Roles of lymphatic endothelial cells expressing peripheral tissue antigens in CD4 T-cell tolerance induction.

Nature communications

Rouhani SJ,Eccles JD,Riccardi P,Peske JD,Tewalt EF,Cohen JN,Liblau R,Mäkinen T,Engelhard VH

14-5698 was used in Flow cytometry/Cell sorting to demonstrate that when β-galactosidase (β-gal) is expressed in LECs, β-gal-specific CD8 T cells undergo deletion via the PD-1/PD-L1 and LAG-3/MHC-II pathways.

Fri Apr 10 00:00:00 EDT 2015

DNAM-1 expression marks an alternative program of NK cell maturation.

Cell reports

Martinet L,Ferrari De Andrade L,Guillerey C,Lee JS,Liu J,Souza-Fonseca-Guimaraes F,Hutchinson DS,Kolesnik TB,Nicholson SE,Huntington ND,Smyth MJ

14-5698 was used in Flow cytometry/Cell sorting to reveal the existence of a functional program of NK cell maturation marked by DNAM-1 expression.

Tue Apr 07 00:00:00 EDT 2015

Potential role of IL-17-producing iNKT cells in type 1 diabetes.

PloS one

Li S,Joseph C,Becourt C,Klibi J,Luce S,Dubois-Laforgue D,Larger E,Boitard C,Benlagha K

14-5698 was used in Flow cytometry/Cell sorting to investigate the status and potential role of iNKT17 in type 1 diabetes.

Thu Jan 22 00:00:00 EST 2015

The adhesion G protein-coupled receptor GPR56 is a cell-autonomous regulator of oligodendrocyte development.

Nature communications

Giera S,Deng Y,Luo R,Ackerman SD,Mogha A,Monk KR,Ying Y,Jeong SJ,Makinodan M,Bialas AR,Chang BS,Stevens B,Corfas G,Piao X

Published figure using Ki-67 monoclonal antibody (Product # 14-5698-82) in Immunofluorescence

Wed Jan 21 00:00:00 EST 2015

Myeloid cells expressing VEGF and arginase-1 following uptake of damaged retinal pigment epithelium suggests potential mechanism that drives the onset of choroidal angiogenesis in mice.

PloS one

Liu J,Copland DA,Horie S,Wu WK,Chen M,Xu Y,Paul Morgan B,Mack M,Xu H,Nicholson LB,Dick AD

Published figure using Ki-67 monoclonal antibody (Product # 14-5698-82) in Immunofluorescence

Thu Jan 15 00:00:00 EST 2015

Role of testicular luminal factors on Basal cell elongation and proliferation in the mouse epididymis.

Biology of reproduction

Kim B,Roy J,Shum WW,Da Silva N,Breton S

14-5698 was used in Immunohistochemistry to conclude that luminal testicular factors play an important role in basal cells extending their body projections towards the lumen.

Thu Jan 01 00:00:00 EST 2015

Cytoskeletal regulation by AUTS2 in neuronal migration and neuritogenesis.

Cell reports

Hori K,Nagai T,Shan W,Sakamoto A,Taya S,Hashimoto R,Hayashi T,Abe M,Yamazaki M,Nakao K,Nishioka T,Sakimura K,Yamada K,Kaibuchi K,Hoshino M

14-5698 was used in Immunofluorescence to demonstrate a role for cytoplasmic AUTS2 in the regulation of Rho family GTPases contributing to neural development.

Wed Dec 24 00:00:00 EST 2014

Metastasis is regulated via microRNA-200/ZEB1 axis control of tumour cell PD-L1 expression and intratumoral immunosuppression.

Nature communications

Chen L,Gibbons DL,Goswami S,Cortez MA,Ahn YH,Byers LA,Zhang X,Yi X,Dwyer D,Lin W,Diao L,Wang J,Roybal J,Patel M,Ungewiss C,Peng D,Antonia S,Mediavilla-Varela M,Robertson G,Suraokar M,Welsh JW,Erez B,Wistuba II,Chen L,Peng D,Wang S,Ullrich SE,Heymach JV,Kurie JM,Qin FX

Published figure using Ki-67 monoclonal antibody (Product # 14-5698-82) in Flow Cytometry

Tue Oct 28 00:00:00 EDT 2014

CD28 expression is required after T cell priming for helper T cell responses and protective immunity to infection.

eLife

Linterman MA,Denton AE,Divekar DP,Zvetkova I,Kane L,Ferreira C,Veldhoen M,Clare S,Dougan G,Espéli M,Smith KG

14-5698 was used in Flow cytometry/Cell sorting to determine the role for CD28 after T cell priming.

Mon Oct 27 00:00:00 EDT 2014

Differential developmental requirement and peripheral regulation for dermal Vγ4 and Vγ6T17 cells in health and inflammation.

Nature communications

Cai Y,Xue F,Fleming C,Yang J,Ding C,Ma Y,Liu M,Zhang HG,Zheng J,Xiong N,Yan J

14-5698 was used in Flow cytometry/Cell sorting to reveal a differential developmental requirement and peripheral regulation for dermal Vγ6 and Vγ4 γδT cells.

Mon Jun 09 00:00:00 EDT 2014

Alveolar progenitor and stem cells in lung development, renewal and cancer.

Nature

Desai TJ,Brownfield DG,Krasnow MA

Published figure using Ki-67 monoclonal antibody (Product # 14-5698-82) in Immunofluorescence

Thu Mar 13 00:00:00 EDT 2014

Hematopoietic stem and progenitor cell activation during chronic dermatitis provoked by constitutively active aryl-hydrocarbon receptor driven by Keratin 14 promoter.

Toxicological sciences : an official journal of the Society of Toxicology

Murakami S,Yamamoto M,Motohashi H

14-5698 was used in Flow cytometry/Cell sorting to analyse the bone marrow and spleen of transgenic mice to understand how aryl-hydrocarbon receptor-provoked allergy affects haematopoiesis.

Sat Mar 01 00:00:00 EST 2014

Intratumoral IL-12 combined with CTLA-4 blockade elicits T cell-mediated glioma rejection.

The Journal of experimental medicine

Vom Berg J,Vrohlings M,Haller S,Haimovici A,Kulig P,Sledzinska A,Weller M,Becher B

14-5698 was used in Flow cytometry/Cell sorting to study intratumoral elicitors of T-cell mediated glioma rejection.

Mon Dec 16 00:00:00 EST 2013

Dedifferentiation of committed epithelial cells into stem cells in vivo.

Nature

Tata PR,Mou H,Pardo-Saganta A,Zhao R,Prabhu M,Law BM,Vinarsky V,Cho JL,Breton S,Sahay A,Medoff BD,Rajagopal J

Published figure using Ki-67 monoclonal antibody (Product # 14-5698-82) in Immunofluorescence

Thu Nov 14 00:00:00 EST 2013

Small intestine inflammation in Roquin-mutant and Roquin-deficient mice.

PloS one

Schaefer JS,Montufar-Solis D,Nakra N,Vigneswaran N,Klein JR

Published figure using Ki-67 monoclonal antibody (Product # 14-5698-82) in Flow Cytometry

Tue Sep 03 00:00:00 EDT 2013

Anti-CTLA-4 antibodies of IgG2a isotype enhance antitumor activity through reduction of intratumoral regulatory T cells.

Cancer immunology research

Selby MJ,Engelhardt JJ,Quigley M,Henning KA,Chen T,Srinivasan M,Korman AJ

14-5698 was used in Flow cytometry/Cell sorting to analyse the mechanism of action of anti-CTLA-4 antibodies against tumours in greater detail.

Mon Jul 01 00:00:00 EDT 2013

Primate B-1 cells generate antigen-specific B cell responses to T cell-independent type 2 antigens.

Journal of immunology (Baltimore, Md. : 1950)

Yammani RD,Haas KM

Mon Apr 01 00:00:00 EDT 2013

IL-1R signaling in dendritic cells replaces pattern-recognition receptors in promoting CD8⁺ T cell responses to influenza A virus.

Nature immunology

Pang IK,Ichinohe T,Iwasaki A

Fri Mar 01 00:00:00 EST 2013

Regulatory T cells in γ irradiation-induced immune suppression.

PloS one

McFarland HI,Puig M,Grajkowska LT,Tsuji K,Lee JP,Mason KP,Verthelyi D,Rosenberg AS

14-5698 was used in Flow cytometry/Cell sorting to show that in mice primed to an MHC class I alloantigen, the accelerated graft rejection T memory response is specifically lost several weeks following TBI.

Wed Dec 12 00:00:00 EST 2012

Bioinformatics

Protein Aliases: Antigen identified by monoclonal antibody Ki-67; Antigen identified by monoclonal antibody Ki-67 homolog; Antigen KI-67; Antigen KI-67 homolog; Proliferation marker protein Ki-67; proliferation-related Ki-67 antigen; protein phosphatase 1, regulatory subunit 105; RP11-380J17.2; unnamed protein product

Gene Aliases: D630048A14Rik; Ki-67; Ki67; KIA; MIB-; MIB-1; MKI67; PPP1R105

UniProt ID: (Human) P46013, (Mouse) E9PVX6

Entrez Gene ID: (Dog) 100686578, (Human) 4288, (Cynomolgus monkey) 102135895, (Rat) 291234, (Mouse) 17345

Function(s)

DNA metabolic process meiotic nuclear division cell proliferation response to organic cyclic compound hyaluronan metabolic process organ regeneration cellular response to heat hepatocyte proliferation cholangiocyte proliferation

Process(es)

protein binding ATP binding protein C-terminus binding poly(A) RNA binding molecular_function